Remeron Withdrawal Abdominal Cramps
Posted , 9 users are following.
Hello, I have posted here before, and some of you will remember. I am on my third and last withdrawal from mirt. I was having horrible abdominal cramps from the second attempt, and at the advice of my GI doc went back on 3.75. Within a few days, the abdominal symptoms were gone. However heart rhythm side effects force me to drop them after only a couple of months. I was hoping that the cramps were gone, but I wasn't that fortunate. Slowly, day by day, they returned, along with the normal WD symptoms. It has been over 80 days, and I am back using the heating pad for the pain. If this scenario is in anyway similar to your experience, or that of someone you know, would you please let me know. I know that no two people are the same, but to know that someone gradually had the abdominal cramps go with time, it sure would help with my anxiety / stress / peace of mind. I thank you, David. I first started trying to get off mirt about two years ago, and have been sick from withdrawals / side effects for the whole time, except last November when I went on the 3.75. Also, for anyone reading this, if you are on the Remeron road of hell, I wish you Godspeed in reaching the end!
0 likes, 90 replies
linda55581 david28533
Posted
Linda
joe12453 linda55581
Posted
I have the same symptoms.
I withdrawed slowly and I am now off of it for 1 month approximately. I still feel sometimes nauseous, sometimes my abdomen hurts and my stool is not as firm as it used to be (sometimes even diarrhea), but my work is also a little stressful at the moment.
I would also be interested in David’s status.
linda55581 joe12453
Posted
joe12453 linda55581
Posted
I have no trouble falling asleep, but I wake up a little earlier than usual, which is not that bad.
In about a month time, I went from 78 kg to 74 kg, which is approximately the weight I had before taking the med. I monitor my weight daily and try to eat enough, but some reduction in appetite is normal I guess, even without withdrawals, as Mirt increases the appetite.
My main problem is that sometimes I have abdominal pain / an agitated bowel, whereas other times I have quite a bit nausea. But those symptoms never seem to be happening on the same time, which is good.
I rarely read about people having WD’s significantly longer than a few months, which I think is good news - we may be free soon. I however often read that people still have some symptoms after about a month, which is our case.
joe12453
Posted
linda55581 joe12453
Posted
It’s a rather strange feeling which I think is related to the pain in my lower left abdomen. I had a series of tests done when I withdrew the first time, but everything tested fine, so I really think that it’s related to the mirtazipine withdrawal. It just seems so strange, but it is heartening to know that others are experiencing the same thing. I would just like to hear from someone that the abdominal pain and nausea per se’ finally went away without their going back on the mirtazipine. Btw, my nausea and pain are at the same time. And I fall asleep ok, but without a sleep aid awake between 2-3 and cant fall back to sleep.
joe12453 linda55581
Posted
Seems like nearly exactly my problems regarding sleep, pain, and nausea... I also feel sometimes like I need to go to the toilet, but don’t !
At least this gives a little reassurance that these symptoms aren’t really related to a certain disease, but « only » withdrawal.
I also am confident that they will go away without going back on the medication, there is really no reason why they wouldn’t.
Strange thing in my situation is that I was for nearly a month on 1.85 mg and didn’t really notice any of those symptoms. It only started when I stopped completely.
Finally, I would like to add that I was on this medication only because of minor sleep troubles, and that, if I had known the problems related to withdrawal, I would never even have started taking it...
linda55581 joe12453
Posted
Thx so much for sharing. Would like to maintain contact. Linda
joe12453 linda55581
Posted
Yes, it’s really great to be able to talk to somebody with basically the same « problem ». To motivate myself, I just think about all the bad symptoms I have been fighting for a month now. If I’d just get back to the medication, all of that would have been in vain. Also, I rarely read about people complaining about WD after several months, so I think we may be close...
Furthermore, I found that an occasional benzo and/or immodium really help with my symptoms. Also, if you don’t exceed 2-3 low-dosed benzos a week, you should not become dependent, so there won’t be any WD regarding those meds that help going through that rough time. I am trying some probiotics at the moment, but can’t yet say if they help.
Like you, I also meditate daily, using the « Headspace » app. Exercise is also great to help reduce those WD symptoms, but I limit it to the days where my bowel is less irritated.
linda55581 joe12453
Posted
Do you take the benzos for sleep or anxiety. Any side affects. Sometimes when I take another med, I can’t tell what is doing what. But I cannot afford to go with so little sleep. It magnifies everything.
You make a good point about motivation. That is a good way of looking at it.
I hope you are right when you say we are hopefully near the end of the WD👍
linda55581 joe12453
Posted
joe12453 linda55581
Posted
Sleep is a minor problem for me, so I usually take them only on stressful days when I want to calm down a bit during the day. It looks like they also improve some of the other symptoms, but I am very careful. My GP told me that they can help with the withdrawal, as long as I stay below 2-3 per week (to not risk a dependence and WD from them)
Motilium (Domperidone) also seems to work to treat the nausea that sometimes arises. Have you tried that?
ann55375 linda55581
Posted
linda55581 joe12453
Posted
Hi Joe
No I have not taken anything for nausea, but am seeing my dr today and will ask. I experimented a bit yesterday, with a couple of supplements my chiropractor recommended. Htp by biopics research and Nevaton m1380 by standard process (suppose to help the brain readjust quicker when doing a WD. ). The HTp settles me down and readies me for sleep by increasing the seratonin. I took 1 of each around 5:30 and then 1 htp only 1 hour before bed. I also decreased my trazadone from 75m to 50. I must say I feel much less crazed this morning and first time arising without pain and juust slight nausea Just one day but hopefully the beginning of many. I will keep you posted. I’d like to remove the trazadone in time, but will probably reduce it more initially. Btw, I am also doing an App called Braintime. It’s supposed to help reregulate the brain and help with sleep, anxiety and focus. Not sure what is doing what but I sure feel better today.
linda55581 ann55375
Posted
linda55581 joe12453
Posted
joe12453 linda55581
Posted
What I forgot to ask until now : How long did you take Mirt in total? I think a lot of WD has also to do with how long one has been taking a medication.
linda55581 joe12453
Posted
I was on mirtazipine a few times. The first time, I am not sure, perhaps 3 years and a higher dose (30). I think I came off it too soon and that is when I got so sick and lost a ton of weight. This second time I was on 15m probably for 9 months at which time I started a very slow WD.
joe12453 linda55581
Posted
Many thanks for your long reply.
Is it 5-HTP you are referring to? I did not try any of those supplements yet, but I’ll have a look.
I see you are also on Trazodone. If I recall correctly, my GP told me that Trazodone would be an alternative to Mirtazapine (sleep quality wise). Did you start it after quitting Mirt?
Today, like you, I felt no cramps at all, but slight nausea which was easily fixed by Domperidone (Motilium). Litican 20 is also an alternative to Motilium if you are looking for anti-nausea meds.
Let’s see how it goes...
linda55581 joe12453
Posted
Also my doctor told me there is a homeopathic mirtazipine. He thought taking that would help clear all the mirtazipine “energy” from my body. I am going to give it a try. I’d really like to avoid chemicals if at all possible - too many side affects.
joe12453 linda55581
Posted
Regarding this homeopathic mirtazapine you are referring to, do you have the name of it by any chance?
I also thought about the IBS-like symptoms from Mirtazapine WD and was thinking that this may also be partly due to the IBS-improving effect of Mirtazapine. I read that it can be used off-label to treat IBS symptoms. Before I went on Mirtazapine, I had some minor IBS symptoms which improved during the treatment. I guess that I was used to having close to no IBS symptoms during my 2 years of treatment and that now I am slowly going back to my old symptoms (which are currently worse than before treatment, but I guess that’s also part of the WD).
I also note that cramps (and pain) only arise in the morning, as soon as I wake up at around 5h00, which Iast a few hours. I usually have a single, somewhat mushy bowel movement in the morning and then won’t need to go to the toilet again until the next day.
To treat the cramps and pain, I went to get some Hyoscine butylbromide (Buscopan).
ann55375 linda55581
Posted
ann55375 joe12453
Posted
joe12453 ann55375
Posted
Did you ever have IBS symptoms during WD? If so, how long did they last?
linda55581 joe12453
Posted
I will let you know when I find out more on the mirtazipine.
Ann, I too have an overactive bladder. Never associated it with mirtazipine but it’s veery possible. Will see what happens as I continue to clear out the mirtazipine.
joe12453 linda55581
Posted
Another question: Did anyone test their cholesterol levels while taking Mirtazapine? I had elevated cholesterol values during my treatment, but I did some research and found that they also can have an effect on these levels. Now that I am off of it, they already lowered quite a bit.
linda55581 joe12453
Posted
As for pain today - hardly noticeable, and some nausea. There is still a fair amount of anxiety though and afternoon fatigue. Suspect I just need to be patient with this process. I think all three of us have noticed some changes, so that is encouraging
linda55581 ann55375
Posted
joe12453 linda55581
Posted
I now know why I didn’t take 5-HTP so far. Common side effects are loss of appetite, which I didn’t want to have as my appetite is already very low. So I try go through WD by only taking probiotics and another vitamin supplement.
ann55375 linda55581
Posted
I seem to be feeliing worse each day as i go along this route. I had hoped to feel better. Dr has referred me to urologist but im sure the bladder frequency is CNS changes due to mkrtazapine as it wasnt there when i was on it. I am now stuck with only diazepam formthe anxiety whichnpsychiatrist says is my problem and i think he's wrong. I am sociallly not right, i am very nervy, i sleep fitfully and i think im now taking too many diazepam. I just feel so generally unwell. Something is wrong and i cant go on like this. I know mirtaz messes you up but i have been off it since February, never well on it but better than this. Gp just doles out the diazepam and tests for uti. I would like to try Homeopath but cant find one in my area.
ann55375 joe12453
Posted
linda55581 joe12453
Posted
joe12453 ann55375
Posted
For how long have you been taking diazepam and how many pills per week? I have some reading knowledge about those meds and may be able to help you.
joe12453 linda55581
Posted
I also think that we need to be sure about how we were feeling before the Mirtazapine and why we were taking them in the first place, so that we can differentiate between WD and our previous mental and physical state. I, for instance, did only take them to improve my sleep, but they also fixed my slight IBS (If I had known what WD symptoms I’d be feeling, I’d never have taken this drug). I guess, in my case, that some IBS is normal even after WD, as it was there before taking the medication.
joe12453 linda55581
Posted
Could be affecting your sleep, I also, but very rarely, feel a slight burning in my stomach... The supplements I take are called « Opti-Men », but they also exist for women, and are called « Opti-Women ». However, I don’t know if they help with WD.
linda55581 joe12453
Posted
Wondering if you go from feeling fairly decent to suddenly feeling very tired with an overall feeling of anxiety. I don’t know if this is new or I am just more aware of it because the abdominal pain has subsided. Also feeling moments where I feel a surge of heat thru my body. All very strange and hopefully short lived
joe12453 linda55581
Posted
Normally I don’t feel that way regarding anxiety, however I often go from nausea to abdominal pain etc. I rarely have those symptoms together, I guess it’s related to being more aware once other symptoms have subsided...
linda55581 joe12453
Posted
Thanks Joe,
Perhaps true as the symptoms dissipate. Now the challenge of getting some sleep. constantly toy with the idea of not using anything to see how it goes, but I hate the thought of losing a night's sleep.
joe12453 linda55581
Posted
ann55375 linda55581
Posted
ann55375 joe12453
Posted
joe12453 ann55375
Posted
If you take still take them regularly or if you did take them quite regularly, some of your symptoms could be caused by WD from diazepam. They also recommend to taper Benzos, if you want to stop taking them. However, if you only take them 1-2 times a week, there shouldn’t be many withdrawal symptoms, unless you took more before.
linda55581 ann55375
Posted
Ann, I am in Boston. If you want to share your personal email with me, I'd be happy to reply
linda55581 joe12453
Posted
joe12453 linda55581
Posted
linda55581 joe12453
Posted
Almost fell asleep without anything last night until the phone rang then my head took over. Ended up taking NyQuil as I had a bad post nasal drip. Slept like a baby and not much sleep hangover this morning. Hoping to have a good day and will try again to go without meds tonight. How are you doing?
joe12453 linda55581
Posted
I am quite OK at the moment. IBS seems to be better now than last week. I slept from 22h30 to 4h50, was then awake a bit and dozed until 6h30, which is quite OK - I did not take any sleepaid. However, most days I wake up later than 4h50, which is good.
I hope it stays this way, as I will go on vacation soon.
linda55581 joe12453
Posted
joe12453 linda55581
Posted
Funny thing is, yesterday, I also went to bed at around 10:30 and woke up more or less at 3:30... However, I didn’t experience any hot flashes during my WD, at least until now. I do experience some night sweats, but that could also be due to the current temperatures...
Overall, my IBS seems to be better now. Could be due to the probiotics I take for about a week now, or just because they WD symptoms are slowly fading away. I hope it’s the WD fading.
linda55581 joe12453
Posted
joe12453 linda55581
Posted
I always had some mild IBS symptoms before taking the medication. However, Mirt seems to have improved my IBS and, during the 2 years I was taking it, I more or less forgot about my IBS symptoms. Now that they come back, I slowly start to remember how it was before the medication.
linda55581 joe12453
Posted
I am not sure, but I think I am worse since I started taking the homeopathic mirtazipine. The fatigue and nausea are back and an overall feeling of agitation and anxiety. Not a happy camper.
joe12453 linda55581
Posted
I think an idea would be to take no medication at all for a few days (not including vital medication of course), to check what your current state is without any other influences. I, for instance, only take Probiotics at the moment and don’t feel too bad, a few IBS symptoms but more or less OK. I’ve not taken any Mirt now for 40 days.
linda55581 joe12453
Posted
joe12453 linda55581
Posted
After stressful weeks at work, I am finally on vacation since saturday. Right now, I am not putting any stress on myself and my symptoms seem to have faded nearly completely - I wake up at around 6h00-7h00 in the morning, which is quite OK and have close to no IBS cramps at the moment. So I think a lot of the symptoms were caused by a combination of WD and stress.
Last time you told me that you have a quite active life - aren’t there any ways you could try to remove some of the stress factors for some time to test if this also helps your symptoms?
linda55581 joe12453
Posted
Yes, Good advice. I have been cutting back on my busy schedule. Hopefully that will help somewhat. However I do find that sometimes it is a good distraction to have some commitments.
I meant to ask you if you’ve taken anything for nausea in the past and if that helped. I am beginning to lose weight and that is not a good thing for me.
So glad to hear you are doing so well. Sounds like you have a successful withdrawal. Did the nausea end quite suddenly?
joe12453 linda55581
Posted
I had (only) intermittent nausea during my withdrawal and I took some domperidone (Motilium) or alizapride (Litican), but not more than one per day. I think 5-6 in total during the last weeks. It helped with nausea, and both medications seem to have worked for me.
Now that I am on vacation, I did not have any nausea so far, so I did not take any. I guess the vacation caused my stress-level to drop and so did the nausea and IBS.
I am not sure if my WD is over now, I’ll have to see how it will be once I get back to everyday stress ;-)
linda55581 joe12453
Posted
I am inclined to think that your withdrawal symptoms are pretty much gone but that now it’s a matter of trying to take care of the anxiety caused by work. I know full well that is easier said than done. I wonder if your adrenals are a bit weakened from the med/ withdrawal cycle and all will be easier to deal with once these are back in check. I wonder if an adrenal support remedy may be helpful.
Are those meds for nausea prescription?
Anything you can change at work to reduce the pressure?
joe12453 linda55581
Posted
In Europe those nausea meds require a prescription, but I don’t know if it is the same in the US.
I will get back to work soon and report back how I am feeling. The last days have been good so far, no anxiety, no nausea, no IBS, basically no symptoms.
How are you doing?
linda55581 joe12453
Posted
Sleeping is an issue for me. Last night was the best, i took 2 benydryl (for the first time) which is basically an antihistamine. ( I think an antihistamine is also in mirtazipine). Upon awaking this morning, i got an overal feeling of nausea/ anxiety with some tingling on the bottom of my feet. This has been typical for me. It is a feeling that comes and goes throughput the day. Anyhow, I just took 4m of ondansetron, also for the fist time. It’s a mild prescription for nausea. It will be interesting to see how this goes. So far after 20minutes I am feeling better, but feet still tingle. Stay tuned.
It will be interesting to see how you do once back at work. Good luck and please keep me posted
joe12453 linda55581
Posted
Sorry that it’s been a while. I was back at work and then again on vacation. I can say now that I am feeling better, but some days, I have some mild IBS symptoms, which was the case before the medication.
How are you?
ann55375 linda55581
Posted
linda55581 joe12453
Posted
My symptoms got so bad I had to go back on mirt (7,5). I had started to lose weight again and was afraid I would get too thin like a year ago. However I was having too many other side affects so doctor has put me on a different med with the idea that I will come off the mirt, as the other settles in. After 4 days on the new med, I am feeling more and more like myself.
Anxiety is something my father and four siblings have dealt with as they got older, do I think it is in my dna. If this new med continues to work, and I can come off the mirt, i will be thrilled as I am beginning to feel so much better. Once off the mirt, the underlying fatigue should go away.
linda55581 ann55375
Posted
ann55375 linda55581
Posted
linda55581 ann55375
Posted
When the fatigue and anxiety become overwhelming it totally impacts our lives - I did not want that to happen again. When I went back on the mirtazipine, I realized it was not good for me,and the dna testing proved that to be true. If a doctor (psychiatrist did it for me) can not do it, you may be able to do the DNA testing on your own. It was just a swab of the inner cheek with a qtip.
I hope this testing is available for you Anne. After one week on the new med, I have no anxiety -and the fatigue is not gone but much better. I am hoping once I come off the mirt, all the negatives will be gone.
L
lee84942 linda55581
Posted
Hi, I know this an old thread. Id like to know how youre all doing 9-10 months on from the last discussions.
Im now off 7,5mg cold turkey for almost 8 months and still having horrendous stomach issues from time to time. I also feel I have numerous grain/carb intollerances which seem permanent. I also cannot tollerate any synthetic/derived sugars. Also having nausea, gut/brain axis issues and CNS issues.
Ive lost in total 20kg (44lbs) and still losing on avg. 1kg per 1-2 weeks. Been scoped both ends and all that was found was a speculative Celiac diagnosis with lymhpocytes in the duodenum biopsy at 68/100 (normal is below 25/100). The Celiac Marsh score was 1 without atrophy, so no villi intestinal damage.
ann55375 lee84942
Posted
i am still in a really bad place. i am now 16 months off mirtazapine and have tried other anti deps since but they made me worse so no success. i am in tolerance at 9mg diazepam daily and still feel terrible. sleep,is not good, appetite down, nausea and ibs constand companions. i blame most of this on diazepam as i was fiven it for pain and now i am depressed and anxious about my lifd not being normal,anymore. it is a veru hard drug to come off and i aam sure caused all of this. we are all suffering from drugs we should never have taken. how this will all end i dont know but it has ruined my life. i am still searching for a solution
ann55375 linda55581
Posted
linda what did you take which helped you?
ann55375 joe12453
Posted
i know you mentioned last year you had some good info on diazepam. if youre aroundi would appreciate thoughts
linda55581 ann55375
Posted
i was on trintellix (1/2 pill every other day i felt so good that i came off it i think that was a mistake trying to get back on
ann55375 linda55581
Posted
please let me know how you do if you restart it. i would be interested in trying it
linda55581 ann55375
Posted
hi ANN I am doing 1/2 trintellix every other night i am just on the third day so difficult to say if it is helping or hurting i still experience nausea and am taking lorazapam to dull the anxiety and nausea yesterday i needed it morning and night i am afraid of becoming addicted to it
last night was my night off tintrellix so i took cbd oil slept well untill 3:45 then off and on until 5:30
i am seeing a new doctor tomorrow i am beginning to think this may have more to do with my adrenals i am hoping she can figure this out i am not convinced it is depression
siobhan60787 linda55581
Posted
Hi, Linda, Ann, Joel & co - its been a while since you've posted and I'm wondering if you're still about - I've read all your posts and its like looking in a mirror - as I'm in the uk my physc made me discontinue Mirtazapine at 7.5mg, ive been off 3 weeks and all the gastro issues are horrendous, i can barely go out because of nausea and bowels - i just wondered how you are all doing, maybe there's some encouraging news but in any event i do hope you are all about and doing well because i really want to stick this out, as you name a WD and i think I'm experiencing it thanks all