Can I take Aspirin and Atorvastatin together?

Why this happens

Aspirin works by making the blood less 'sticky' (antiplatelet), while atorvastatin works by lowering cholesterol in the liver. Because they work in completely different ways and are processed by different pathways in the body, they do not interfere with each other.

What you should do

You can safely take these medicines together as prescribed by your doctor. It is usually recommended to take atorvastatin in the evening, while aspirin is often taken after a meal to protect your stomach.

Important precautions

Asthma

Do not take aspirin if you have a history of asthma triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can cause a severe, life-threatening allergic reaction or asthma attack.

Pregnancy

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it may cause serious harm to an unborn baby. Use effective contraception while taking it.

Unexplained muscle pain - atorvastatin

Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to serious kidney problems.

Food and drink warnings

Grapefruit juice

Grapefruit juice can increase the level of atorvastatin in your blood, which may increase the risk of side effects like muscle pain. Avoid drinking large amounts (more than 1.2 litres a day), though a small glass is usually fine.

Alcohol

Drinking alcohol while taking aspirin increases the risk of stomach irritation and bleeding. For atorvastatin, regular heavy drinking increases the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits.

Food (General)

Aspirin should ideally be taken with or just after food. This helps to protect your stomach lining and reduces the risk of indigestion or stomach irritation.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.