Latest studies
- Completed
Barriers and facilitators to deprescribing antithrombotic therapy in advanced cancer patients: A qualitative interview study of patients’, companions’ and clinicians’ experiences and perspectives
This study looks at how people with advanced cancer feel about taking blood-thinning medicines. Researchers want to understand patients' and carers' views on whether and when to stop these treatments. Taking part involves a single 30 to 60-minute interview. The findings will help build a new decision-making app for future patients.
Cancer and deprescribing antithrombotic therapy at end-of-lifeDenmark - Completed
Integrated short-term palliative rehabilitation in incurable cancer
This clinical trial investigates whether a short rehabilitation programme can help people with advanced, incurable cancer stay independent and improve their quality of life. Participants receive either standard care alone or standard care with up to three specialist rehabilitation sessions, along with answering questionnaires about their daily wellbeing over 16 weeks.
Advanced incurable solid cancer: lung, colorectal, breast, prostate, etc.Denmark - RecruitingPhase I/II
A trial looking at different treatments for neuroblastoma which has come back after initial therapy
The BEACON2 trial is testing new combinations of cancer medicines for children and young people whose neuroblastoma has returned or worsened after initial treatment. The goal is to find out which drug combinations are safest and work best to control the disease and improve future care.
Relapsed NeuroblastomaDenmark - RecruitingPhase I
A study of JNJ-95804306 for relapsed or refractory hematological malignancies
This early-stage clinical trial is testing a new medicine called JNJ-95804306 for adults with blood cancers that have returned or stopped responding to standard treatments. Doctors want to find safe doses and check how well the body handles the drug when given alone or with other cancer therapies.
Hematologic neoplasms, blood cancerDenmark - RecruitingPHASE3
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
This study looks at new ways to treat type 2 diabetes by testing two medicines, Elecoglipron and Dapagliflozin, both on their own and together. Researchers want to see how well they work and if they are safe for adults with type 2 diabetes.
Type 2 Diabetes MellitusDenmark - RecruitingPHASE3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
This study is testing a new medicine, Elecoglipron, for adults with type 2 diabetes and kidney problems. It compares Elecoglipron to a dummy pill (placebo) to see if it's safe and effective when taken with other usual diabetes medicines, including dapagliflozin.
Type 2 Diabetes MellitusType 2 Diabetes With Chronic Kidney DiseaseDenmark - RecruitingPhase II
Finding the best treatment for lung disease from infection with Mycobacterium abscessus
This clinical trial is testing different combinations of antibiotics to find the best way to treat lung infections caused by Mycobacterium abscessus. The goal is to discover which medicines work best to clear the bacteria while causing the fewest and least severe side effects for patients.
Mycobacterium abscessus pulmonary diseaseDenmark - Completed
Vitamin D and lifestyle Intervention for gestational diabetes mellitus (GDM) prevention
This study looks at ways to prevent gestational diabetes, which is high blood sugar during pregnancy. Researchers are testing whether vitamin D supplements, healthy eating advice, regular physical activity, or combinations of these can help pregnant women with a higher body mass index stay healthy throughout their pregnancy.
Gestational diabetesDenmark - RecruitingPhase II/III
Optimising therapy in FLT3-mutated acute myeloid leukaemia
This clinical trial looks at the best chemotherapy combinations for people newly diagnosed with acute myeloid leukaemia (AML) who have a specific gene change called FLT3. It compares current standard treatment with two new drug mixtures to see which clears the cancer best and prevents it from returning.
Acute myeloid leukemiaDenmark - RecruitingPHASE2, PHASE3
A Safety and Efficacy Study of hu14 in High-Risk Neuroblastoma Patients
This study is testing a new treatment called hu14.18K322A, given with chemotherapy, for children and young people with a type of cancer called high-risk neuroblastoma. It aims to see if this combination treatment is safe and effective in fighting the cancer.
High-Risk NeuroblastomaDenmark - RecruitingPHASE2
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
This study is testing a new medicine called belzutifan for certain types of advanced cancers, including rare adrenal gland, gut, and kidney cancers. We want to see how well it works and if it's safe for people aged 12 and over.
Pheochromocytoma/ParagangliomaPancreatic Neuroendocrine TumorVon Hippel-Lindau DiseaseAdvanced Gastrointestinal Stromal TumorDenmark - RecruitingPhase III
Tranexamic acid (and Desmopressin) for very early bleeds in the brain
This clinical trial tests whether an affordable medicine called tranexamic acid can stop bleeding in the brain after a stroke. Doctors want to see if giving this injection quickly in the emergency room helps people survive with less long-term disability, improving recovery and everyday life six months later.
Hyperacute primary intracerebral haemorrhage (stroke)Denmark - RecruitingPhase III
A study of JNJ-78934804 in participants with moderately to severely active Crohn's disease
This clinical trial is testing a new combination medicine, JNJ-78934804, for moderate to severe Crohn’s disease. It combines two drugs into one injection to target gut inflammation. Researchers want to see if this two-in-one approach works better than a single medicine for people whose previous treatments have stopped working.
Crohn’s diseaseDenmark - CompletedPhase II/III
ENRICH Ibrutinib for untreated mantle cell lymphoma
The ENRICH study is testing a targeted medicine called ibrutinib for people aged 60 and older who have newly diagnosed mantle cell lymphoma. Researchers want to see if ibrutinib, taken with an antibody drug, works better and causes fewer side effects than traditional chemotherapy.
Mantle cell lymphoma (MCL)Denmark - AuthorisedHuman Pharmacology (Phase I)- First administration to humans
A phase 1 first-in-human study of a phenylalanine-binding polymer (phelimin) in healthy volunteers and adult, classical PKU patients
This early-stage clinical trial tests a new medicine called phelimin for phenylketonuria (PKU). It is the first time phelimin is being given to humans. Researchers want to check if it is safe and see how it works in healthy adult men and men living with classical PKU.
PhenylketonuriaDenmark - AuthorisedTherapeutic confirmatory (Phase III)
A Long-term Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder for Treatment of Pulmonary Hypertension Associated with Interstitial Lung Disease
This study tests an inhaled dry powder medicine called treprostinil palmitil for adults with high blood pressure in the lungs linked to lung scarring. The trial lasts up to two years to see if the medicine is safe and helps improve breathing, walking ability, and overall quality of life.
Pulmonary Hypertension Associated with Interstitial Lung DiseaseDenmark - AuthorisedTherapeutic use (Phase IV)
Optimising Arthritis Strategies in Elderly patients (≥70 years) with rheumatoid arthritis in sustained low disease activity (the OASE study): A Prospective Target Trial Emulation Study Evaluating Tapering of Disease-Modifying Anti-Rheumatic Drugs vs. Usual Care Based on Patient Preference
This study looks at adults aged 70 and over with well-controlled rheumatoid arthritis. It tests whether slowly lowering their arthritis medication is safe compared to staying on their usual dose. The goal is to find out if reducing medication can lower side effects while keeping arthritis symptoms under control.
Rheumatoid arthritisDenmark - AuthorisedPhase I and Phase II (Integrated)- Other
EXUROC Bladder Target - A phase Ib/ll study to determine the safety, tolerability, and efficacy of LP-184 treatment in patients with advanced/metastatic urothelial carcinoma
This clinical trial is testing a new cancer drug called LP-184 for adults with advanced bladder or urinary tract cancer. Doctors want to find out the safest dose to give, check for side effects, and see if the treatment can help shrink tumours or slow down the cancer.
OncologyDenmark - AuthorisedTherapeutic exploratory (Phase II)
Inducing durable immunological control of HIV-1 through administration of long-acting broadly neutralizing antibodies and low-dose anti-PD-1 – a randomized, double-blinded, placebo-controlled trial (the IDUNN trial)
This study tests whether a combination of specialised immune proteins and an immune-boosting drug can control HIV without daily medication. Participants carefully pause their usual tablets under close medical monitoring to see if the new treatments can keep the virus suppressed on their own.
HIV-1 diseaseDenmark - AuthorisedTherapeutic confirmatory (Phase III)
A Phase III, Multicentre, Randomised, Open-label Study to Compare the Efficacy and Safety of AZD0486 plus Rituximab versus Chemotherapy plus Rituximab in Previously Untreated Participants with Follicular Lymphoma (SOUNDTRACK-F1)
This phase 3 trial is testing a new targeted medicine called surovatamig (AZD0486) combined with rituximab for people newly diagnosed with follicular lymphoma. Researchers want to see if this new combination works better and is safer than standard chemotherapy combined with rituximab.
Follicular LymphomaDenmark - RecruitingPhase I and Phase II (Integrated)- First administration to humans
A Phase 1b/2a first-in-human, multicentre, randomized, double-blind, placebo-controlled study of multiple ascending dose (Part1) followed by an open-label extension (Part2) to assess the safety, tolerability, and pharmacokinetics of intrathecally administered S233107 in participants with spinocerebellar ataxia type 3
This study tests a new experimental drug, S233107, for adults living with spinocerebellar ataxia type 3 (SCA3). Because this is the first time the medicine is tested in people, researchers want to see if it is safe, how well the body handles it, and how it moves through spinal fluid.
Spinocerebellar ataxia type 3Denmark - AuthorisedTherapeutic exploratory (Phase II)
The Danish Anorexia Nervosa Psilocybin RCT (DANP-RCT). A Randomised, Active-Placebo-Controlled, Triple-blind, Superiority Study of Psilocybin-Assisted Acceptance and Commitment Therapy (ACT) in the Treatment of Treatment-resistant Anorexia Nervosa.
This clinical trial is testing whether psilocybin, a medicine paired with talking therapy, can help adult women with severe anorexia nervosa that has not improved with standard care. Researchers want to see if this combination safely reduces symptoms and supports emotional recovery over a 22-week period.
Anorexia nervosaDenmark - AuthorisedTherapeutic exploratory (Phase II)
Botulinum toxin A in the Treatment of Chronic Postsurgical Pain in Lung Cancer Patients: A feasibility study
This study is testing whether small injections of botulinum toxin A (Xeomin) under the skin can help reduce long-term chest pain after lung cancer surgery. Doctors want to see if the treatment is safe, practical, and easy for patients to complete before testing it in larger trials.
Chronic postsurgical pain (CPSP)Denmark - AuthorisedTherapeutic exploratory (Phase II)
An Investigator-Initiated, Descriptive, Proof-of-Concept, Open-Label Pilot Study Focusing on Topical JAK Inhibition as a Novel Treatment of Cutaneous T-Cell Lymphoma
This study tests a new medicated cream called Anzupgo for cutaneous T-cell lymphoma, a rare condition causing skin rashes and itching. Researchers want to see if applying this cream for 16 weeks can calm inflammation, clear skin patches, and relieve uncomfortable symptoms in adults with the condition.
Cutaneous T-cell lymphoma (CTCL)Mycosis fungoidesDenmark - AuthorisedTherapeutic use (Phase IV)
S-KETamine vs. propofol for prehospital sedation of patients with severe Acute Brain Injury: The KETABI randomised trial
This clinical trial compares two emergency sedatives, S-ketamine and propofol, given by paramedics to adults with severe brain injuries. Researchers want to see which medicine is better at keeping blood pressure stable on the way to hospital, protecting the brain from further harm, and supporting long-term recovery.
traumatic brain injury, subarachnoid haemorrhage, intracerebral haemorrhageDenmark - AuthorisedTherapeutic exploratory (Phase II)
Targeting IL-13 in Bullous Pemphigoid: An Investigator-Initiated, Prospective, Multicenter, Proof-of-Concept, Open-Label Pilot Study of Lebrikizumab
This clinical trial is testing a medicine called lebrikizumab (Ebglyss) for people with bullous pemphigoid, a rare condition that causes severe skin blisters and itching. The study looks at whether regular injections over 48 weeks can help clear blisters, calm itching, and reduce the need for strong steroid creams.
Bullous pemphigoidDenmark - AuthorisedTherapeutic exploratory (Phase II)
HOVON 168: Epcoritamab in Addition to R-Mini-CHOP Compared to R-Mini-CHOP in Elderly, Frail or Unfit Patients with Diffuse Large B-cell Lymphoma
This study looks at a new drug combination for older or frail adults with diffuse large B-cell lymphoma, a type of blood cancer. Researchers want to see if adding an antibody drug called epcoritamab to standard, gentler chemotherapy helps clear the cancer better and keeps people well for longer.
Diffuse large B-cell lymphoma (DLBCL)Denmark - AuthorisedTherapeutic exploratory (Phase II)
Randomized, Multicenter, Vehicle-Controlled, Double-Masked Study to Evaluate the Efficacy and Safety of Intranasal Cenegermin (Recombinant Human Nerve Growth Factor [rhNGF]) in Adult Participants with Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)
This clinical trial is testing a new nasal spray called cenegermin for adults with NAION, an eye condition causing sudden sight loss. Researchers want to see if this treatment helps repair damaged nerve cells and improves vision on an eye chart over a period of 24 weeks.
Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)Denmark - AuthorisedTherapeutic confirmatory (Phase III)
Zoledronic acid as prophylaxis against glucocorticoid-induced osteoporosis in lymphoma
Steroid medicines used in lymphoma cancer treatment can weaken bones and raise fracture risks. This study tests whether a bone-strengthening medicine called zoledronic acid can protect bones and prevent breaks over two years in adults having chemotherapy that includes steroids.
Denmark - AuthorisedTherapeutic exploratory (Phase II)
Effects of semaglutide as add-on therapy to sulfonylurea on plasma glucose in individuals with HNF1A- and HNF4A-MODY – A Steno MODERN-MODY project (MM-SEMA)
This study looks at whether adding a weekly injection called semaglutide to standard diabetes tablets can help adults with a rare, inherited type of diabetes (MODY). Researchers want to see if it improves daily blood sugar levels and reduces highs and lows, measured using a wearable continuous glucose sensor.
Maturity-onset diabetes of the young type 3 (HNF1A-MODY), Maturity-onset diabetes of the young type 1 (HNF4A-MODY)Denmark - AuthorisedTherapeutic exploratory (Phase II)
A phase II randomised trial investigating the benefit of adjuvant immunotherapy after neoadjuvant chemoimmunotherapy for resectable NSCLC (ADIL)
This study looks at non-small cell lung cancer that can be treated with surgery. Researchers want to find out if having an immunotherapy drug called Imfinzi after surgery helps stop the cancer from returning, following initial chemo-immunotherapy before surgery. It aims to see if extra treatment improves long-term health.
Non Small Cell Lung Cancer (NSCLC)Denmark - AuthorisedTherapeutic use (Phase IV)
A Pragmatic Randomized Trial to Evaluate the Relative Effectiveness of Abrysvo® Revaccination Versus a Single Primary Dose for Preventing RSV-associated Lower Respiratory Tract Disease in Immunocompromised Adults (DAN-RSV IC REVAX)
This study looks at the RSV vaccine, Abrysvo, in adults with weakened immune systems. Researchers want to find out whether getting a second booster jab gives better protection against serious chest infections and hospital visits than receiving just a single dose.
Respiratory syncytial virus infectionDenmark - AuthorisedTherapeutic confirmatory (Phase III)
A randomized, open-label, multicenter, Phase 3 study to investigate mocertatug rezetecan compared with chemotherapy in participants with endometrial cancer after platinum-based chemotherapy and immunotherapy
This Phase 3 clinical trial tests a new drug called mocertatug rezetecan for womb (endometrial) cancer. Researchers want to see if it works better and is safer than standard chemotherapy for people whose cancer has returned or worsened after earlier treatments like platinum chemotherapy and immunotherapy.
Neoplasms, EndometrialDenmark - AuthorisedTherapeutic exploratory (Phase II)
A Phase 2b, Randomized, Placebo-controlled, Double-blind, Dose-ranging Trial to Assess the Efficacy and Safety of Ontunisertib in Patients with Fibrostenosing Crohn’s Disease
This study tests a new medicine called ontunisertib for people with Crohn's disease who have narrowed sections in their bowel. Researchers want to find out if this daily capsule can reduce tough scar tissue, help widen the bowel, and improve symptoms compared to a dummy pill over one year.
Fibrostenosing Crohn’s DiseaseDenmark - AuthorisedTherapeutic confirmatory (Phase III)
A Phase 3b, Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Lebrikizumab in Adult and Adolescent Participants with Moderate-to-Severe Face and Neck Atopic Dermatitis
This clinical trial is testing a new injection called lebrikizumab for people with moderate-to-severe eczema on their face and neck. Researchers want to see if the medicine can clear skin, soothe itching, and improve daily life over 16 weeks compared to a dummy injection (placebo).
Face and Neck Atopic DermatitisDenmark - AuthorisedTherapeutic confirmatory (Phase III)
A Phase 3 Global, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Demonstrate the Efficacy, Safety, and Tolerability of Claseprubart (DNTH103) in Patients with Generalized Myasthenia Gravis (EMERGE)
This study tests a new medicine called claseprubart (DNTH103) for generalised myasthenia gravis, a condition that causes muscle weakness. Researchers want to see if the medicine safely improves muscle strength and helps with daily activities compared to a dummy drug (placebo) in adults aged 18 and older.
generalized Myasthenia gravisDenmark - AuthorisedTherapeutic exploratory (Phase II)
A Randomized, Double-Blind, Placebo-controlled, Parallel Arm, 52-week Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Two Doses of EXPD-101 in Participants with COPD
This 52-week clinical study is testing an experimental medicine called EXPD-101 for adults living with COPD. Researchers want to find out if taking this treatment can safely reduce chest flare-ups, ease breathing symptoms, and help people stay out of hospital compared with a dummy treatment (placebo).
Chronic Obstructive Pulmonary Disease (COPD) exacerbationsDenmark - AuthorisedTherapeutic exploratory (Phase II)
SEMAGONA: A randomized four-arm parallel group double-blind double dummy 52-week clinical trial comparing the effects of s.c. Semaglutide 2.4 mg once-weekly, i.m. testosterone undecanoate 1,000 mg every 13th week, combination of s.c. Semaglutide 2.4 mg once-weekly and i.m. testosterone undecanoate 1,000 mg every 13th week, and placebo on body composition and hypogonadal symptoms in men with obesity-associated functional hypogonadism
This study tests whether combining a weekly weight-loss injection (semaglutide) with testosterone injections helps men with low testosterone linked to obesity. Researchers want to see if using both medicines together improves muscle mass, reduces body fat, and relieves symptoms better than using either treatment alone or a dummy drug.
Functional hypogonadismDenmark - AuthorisedTherapeutic confirmatory (Phase III)
Prediction and Prevention of Bloodstream Infections After Kidney Transplantation - the PREDICT Study
The PREDICT study looks at whether a common antibiotic called pivmecillinam can help prevent urine and bloodstream infections in people with a new kidney transplant. Researchers are comparing this antibiotic to a dummy pill over six months to see if it safely keeps patients well and protects their new kidney.
Bacterial urinary tract infections and bloodstream infectionsDenmark - AuthorisedTherapeutic exploratory (Phase II)
A randomized, double-blind, placebo-controlled, multicenter Phase 2a/b study assessing the efficacy, safety and tolerability of DDY391 in participants with Sjögren's Disease
This clinical trial is testing a new medicine called DDY391 for adults with Sjögren's disease. Researchers want to see if it safely relieves common symptoms like dry eyes, dry mouth, joint pain, and exhaustion. Participants are randomly chosen to receive either DDY391 or a dummy treatment (placebo).
Sjögren's DiseaseDenmark - RecruitingPhase I and Phase II (Integrated)- First administration to humans
A Phase 1/2 Randomized, Umbrella Study to Evaluate the Efficacy and Safety of MK-2870 Plus Enfortumab Vedotin (EV) With and Without Pembrolizumab, as Treatment for Participants With Advanced Urothelial Carcinoma (KEYMAKER-U04): Substudy 04C
This study tests a new combination of targeted drugs for adults with advanced bladder or urinary tract cancer. Researchers are checking whether a new drug called MK-2870 works safely when given with enfortumab vedotin, with or without an immunotherapy drug, to help shrink tumours and stop cancer growing.
Advanced Urothelial CarcinomaDenmark - RecruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-Blind, Dose Finding and Comparison Study of the Safety and Efficacy of High Doses of Eteplirsen, Preceded by an Open-Label Dose Escalation, in Patients with Duchenne Muscular Dystrophy With Deletion Mutations Amenable to Exon 51 Skipping
This clinical trial is testing whether higher doses of a medicine called eteplirsen are safe and helpful for boys with Duchenne muscular dystrophy. It is for males with a specific genetic change that can be treated by skipping exon 51, aiming to protect muscle strength over nearly three years.
Duchenne Muscular DystrophyDenmark - RecruitingTherapeutic confirmatory (Phase III)
A Phase 3 Global, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)
This study is testing a new injection called ION-682884 for adults with a serious heart condition called ATTR-CM. Researchers want to find out if this medicine can protect the heart, lower the need for hospital care, and help people live longer compared to a dummy treatment (placebo).
Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM)Denmark - RecruitingTherapeutic confirmatory (Phase III)
A Prospective, Multicenter, Long-Term Study to Assess the Safety and Efficacy of Nemolizumab (CD14152) in Subjects with Prurigo Nodularis
This study looks at a medicine called nemolizumab for adults with prurigo nodularis. Prurigo nodularis is a skin condition that causes hard, very itchy lumps. Doctors want to see if nemolizumab is safe and effective at calming severe itch and clearing skin nodules over a longer period.
Prurigo NodularisDenmark - RecruitingPHASE3
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
This study is looking at a new medicine called Danicamtiv for people with a heart condition called genetic or familial Dilated Cardiomyopathy (DCM). It wants to see how well the medicine works over a long time, if it's safe, and if people can take it easily. There are currently no specific medicines for this type of DCM.
Symptomatic Genetic Dilated Cardiomyopathy (DCM)Denmark - RecruitingTherapeutic confirmatory (Phase III)
Prophylactic treatment of breast implants with a solution of gentamicin, vancomycin and cefazolin antibiotics for women undergoing breast reconstructive surgery: a randomized controlled trial (The BREAST-AB trial)
This study looks at whether rinsing breast implants with a special mix of three antibiotics helps prevent serious infections. Researchers want to see if this wash stops women who have breast reconstruction surgery from needing their implants removed or having extra operations within six months to a year.
InfectionDenmark - RecruitingTherapeutic confirmatory (Phase III)
ATHENA (A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 3 Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy)
This study looks at two medicines, rucaparib and nivolumab, for women with advanced ovarian, fallopian tube, or primary peritoneal cancer. It aims to see if using these drugs after standard chemotherapy helps keep the cancer away for longer compared to dummy treatments, known as placebos.
Ovarian epithelialcancer, Malignant peritonealneoplasm, advanced (FIGO stage III-IV), high-grade epithelial ovarian, fallopiantube, or primary peritoneal cancer (who responded to front-lineDenmark - RecruitingTherapeutic exploratory (Phase II)
Evaluation of intra articular Tranexamic acid for reduction of total blood loss in total hip arthroplasty
This study looks at whether injecting a medicine called tranexamic acid directly into the hip joint during hip replacement surgery reduces bleeding. Researchers want to see if this lowers total blood loss during the first two days after surgery for adults with severe hip osteoarthritis.
OsteoarthritisDenmark - RecruitingPhase I and Phase II (Integrated)- Other
Can a one-off administration of psilocybin reduce alcohol intake in patients with alcohol use disorder? A randomized, double-blinded, placebo-controlled clinical trial.
This clinical trial investigates whether a single dose of psilocybin, a compound found in magic mushrooms, can help adults cut down on heavy drinking. Researchers are comparing psilocybin capsules against a dummy treatment (placebo) to see if it reduces alcohol cravings and drinking days over a four-week period.
Alcohol Use DisorderDenmark - RecruitingPhase II and Phase III (Integrated)
A Phase 2/3, Randomized, Double-Blinded, Placebo-Controlled, Parallel-Group, 2-Arm, Multicenter, Operationally Seamless Study to Evaluate the Efficacy, Safety, Tolerability, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of Efgartigimod PH20 SC in Participants Aged 18 Years and Older With Active Idiopathic Inflammatory Myopathy
This clinical trial is testing a new injection called efgartigimod for adults with inflammatory muscle disease (myositis). Researchers want to see if the medicine can safely reduce muscle inflammation, improve strength, and help people lower their daily steroid dose compared to a dummy treatment over 52 weeks.
Active Idiopathic Inflammatory Myopathy (IIM)Denmark