- Recruiting
Incisional heRnia dIgestion Sexuality
This study looks at how hernias after tummy surgery affect patients' daily lives and sexual activity. We're using questionnaires to understand challenges with digestion, posture, and body image, aiming to improve care for these common conditions.
For: Incisional HerniaFrance - RecruitingNA
Characterization of New Phenotypes of Patients With Spinal Muscular Atrophy Treated With SMN Restoring Therapy
This study looks at children under 16 with Spinal Muscular Atrophy (SMA) who are receiving new treatments. We want to understand how these treatments are changing the disease and find the best ways to check on patients' health and progress.
For: Spinal Muscular AtrophyFrance - Recruiting
Associated Psychiatric Disorders in Children Hospitalized for a Serious Suicide Attempt
This study looks into why some children try to take their own lives. We want to understand their characteristics and experiences to help prevent these serious attempts, especially after the COVID-19 pandemic made things worse for many young people.
For: Serious Suicide AttemptFrance - Not yet recruitingNA
5-Year Follow-up of Children and Mother After Expectant Management Versus Induction of Labor in Low-risk Nulliparous Women at 39 Weeks of Gestation
This study looks at children and mothers five years after a French trial compared having labour started early (at 39 weeks) with waiting for labour to begin naturally. Researchers want to see if there are any long-term effects on the child's health, especially brain development.
For: Neurodevelopmental DisordersFrance - Active not recruiting
Adhesion of Children and Adolescents Treated for Cancer to Personalized Support in Adapted Physical Activity Program
This study looks at how to help children and teenagers with cancer keep up with a special exercise programme. It checks what helps and what makes it hard for them and their parents to stick with it, hoping to make these programmes better for everyone.
For: Childhood Cancer · Adapted Physical ActivityFrance - RecruitingNA
Characterization of Social Cognition Profiles in Children and Adolescents With Neurodevelopmental Disorders: a Clinical Study Using a Multidimensional Battery
This study looks at how children and teenagers (8-16) with conditions like ADHD or autism understand social situations. Researchers are using new tests to better understand their social skills. The aim is to help create better support for them in the future.
For: Neurodevelopmental Disorders · Autism Spectrum Disorder · Attention Deficit Hyperactivity DisorderFrance - Not yet recruitingNA
Coping Strategies, Loneliness, and Resilience in Patients With Dermatosis
This study looks at how people with skin conditions cope with their illness, feelings of loneliness, and their ability to bounce back from challenges. Researchers want to understand these experiences better to help improve support for patients.
For: Skin Disease · Skin Disorder · Skin ConditionFrance - Recruiting
Objective Concussion Assessment Using MRI and Metabolomics
This study aims to better understand concussion by looking at how the brain changes after an injury. We'll use special brain scans (MRI) and look at symptoms to see how they connect, helping us diagnose and treat concussions more effectively for people aged 9 to 50 who've recently had a concussion.
For: Concussion, BrainCanada - Recruiting
PACOME (PAtient Cancer Oral MEdication) Cohort of Patients Treated With Oral Anticancer Drugs Benefiting From Oncoral Multidisciplinary Monitoring in Real Life: Predictive Factors and Safety of Treatments
This study looks at how people with cancer taking oral medications at home are supported through a special programme called Oncoral. It aims to understand how well these treatments work in real life and how to make care better for patients outside of the hospital.
For: Cancer · Oncology · Oncoral ProgramFrance - Active not recruitingPHASE3
Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer
This study is looking at a new way to treat early-stage prostate cancer called HIFU. It compares this focused ultrasound treatment to simply watching the cancer closely. We want to see if HIFU can destroy the cancer without the severe side effects of traditional surgery, offering a kinder treatment option.
For: Prostate CancerFrance - Recruiting
Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia
This study looks at teeth discolouration in children who had high bilirubin in their blood when they were younger. We want to see how this affects their quality of life and use the findings to help more children get dental care covered by insurance.
For: Dental DiseasesFrance - Recruiting
Genetic Predisposition to Breast and Ovarian Cancer: Prospective Study of BRCAx Gene Mutation
This study looks at people with a faulty BRCA gene, which increases the risk of breast and ovarian cancers. Researchers want to understand more about how these genes affect health over time by collecting health information.
For: Breast Cancers · Ovarian CancersFrance - Recruiting
Response Profiles to High-concentration Capsaicin Desensitization in Patients with Peripheral Neuropathic Pain with or Without Allodynia: a Regional Multicenter Prospective Cohort
This study looks at how people with nerve pain respond to a special patch containing a high dose of capsaicin. We want to find out why some people get better relief from this treatment than others, especially if they have sensitive skin (allodynia).
For: Peripheral Neuropathic PainFrance - Recruiting
Biobank and Brain Health in Bordeaux.
This study, called "B cube," looks at how our brains change as we get older, especially from age 55. Researchers want to understand why some people's memories and thinking skills decline and how to prevent it. They are studying 2000 people in Bordeaux, France, focusing on things like diet and overall health.
For: Brain · Aging · Cognitive AgingFrance - Not yet recruiting
Determinants and Consequences of the Transition to Adulthood for Adolescents With Severe Haemophilia: TRANSHEMO 2, an Ancillary Study to the TRANSHEMO Project
This study, TRANSHEMO 2, looks at young adults (20-29 years old) with severe haemophilia. It aims to understand how they manage their health as they transition from being a teenager to an adult. Researchers want to find out what helps them stick to their treatment or what might make it harder.
For: HaemophiliaFrance - Not yet recruiting
Study of the Hypothalamic Microglial Response as a Function of a Meal's Lipid Content in Humans. A Single-center Prospective Cohort Study in Healthy Male Subjects
This study looks at how different types of meals affect the brain in healthy men. Specifically, it uses brain scans to see how a part of the brain called the hypothalamus reacts to meals with different fat levels, helping us understand how our bodies control eating.
For: PathophysiologyFrance - Recruiting
Natural History of Photoreceptor Degeneration in USH1B: Clinical Parameters and Validation of Functional Vision Tests in MYO7A
This study looks at Usher syndrome type 1B, a condition causing hearing and vision loss. Researchers want to understand how vision changes over time and test new ways to measure sight using virtual reality and questionnaires. The goal is to help find better ways to track the condition.
For: Usher SyndromeFrance - RecruitingNA
Evaluation of Sleep Changes in Inflammatory Bowel Diseases (IBD) Patients.
This study looks at how sleep changes in people with Inflammatory Bowel Diseases (IBD) who are currently feeling well. We want to see if changes in sleep patterns might predict when their IBD symptoms could return or 'flare up'.
For: Disease Bowel · Crohn Disease · Ulcerative ColitisFrance - Recruiting
Development of a Cough Control Questionnaire (CCQ)
This study is developing a new questionnaire to better understand and measure how cough affects people's lives. It aims to help doctors and researchers accurately track changes in cough severity and how well treatments are working, similar to tools used for other lung conditions like asthma.
For: CoughUnited Kingdom - Recruiting
Oesophagectomy and Chest Wall and Respiratory Function
This study looks at how removing a part of the food pipe (oesophagectomy) for cancer affects breathing and chest movement. It aims to find better ways to measure chest movement and breathing capacity using new technologies, which could lead to improved physiotherapy after surgery.
For: Esophageal Cancer · Esophagectomy · Respiratory Function LossUnited Kingdom - Active not recruiting
Risk Factors for Exertional Heat Illness
This study looks at why some military recruits get sick from exercising intensely in the heat, an illness called Exertional Heat Illness (EHI). Researchers want to find out what makes people more likely to get EHI so they can keep military personnel safe and healthy.
For: Exertional Heat IllnessUnited Kingdom - RecruitingNA
Impact of Parental Training in Endocrine Disruptors on the Excretion of Urinary Biomarkers in Newborns
This study aims to see if simple training for new parents can lower the levels of certain chemicals called endocrine disruptors (EDs) in their newborns' urine. These EDs are found in everyday life and can affect hormones. We want to find out if small changes can make a difference.
For: Endocrine Disruptors in Newborns and InfantsFrance - Recruiting
Long-term Impact of NMDAR Encephalitis, Level 3
This study looks at the long-term effects of a rare brain condition called NMDAR encephalitis. It wants to understand how the illness impacts people's lives socially and psychologically, especially since many patients are young. Researchers will ask participants to complete questionnaires.
For: NMDAR Autoimmune EncephalitisFrance - Not yet recruiting
EMBRACE- BLOOM - Building Literacy and Outcomes Through Observation and Monitoring: Information Needs and Wearable Data in Pregnancy Couples
This study looks at how pregnant women and their partners find and use health information. We want to understand what information they need, where they look for it, and what makes it easy or hard to get trusted advice from early pregnancy until after the baby is born.
For: PregnancyUnited Kingdom - Recruiting
WAMIF: Prospective Study in Young Women Presenting Acute Myocardial Infarction: Cohort Follow up
This study looks at young women under 50 who've had a heart attack. It re-examines their health and quality of life years later. The goal is to better understand their recovery and how to improve future care.
For: Myocardial Infarction, AcuteFrance - RecruitingNA
Prediction in Silico of Pathological Response in a Prospective Cohort Study of Early Breast Cancer Patients
This study aims to better predict how well breast cancer treatments will work for patients with early-stage breast cancer. By collecting detailed information from patients, researchers hope to develop a tool to help doctors choose the best treatment for each person.
For: Breast CancerFrance - Active not recruitingNA
HF-TRACK: A UK RCT of an Passive Heart Failure Monitoring and Tracking Device
This study tests a new device called Heartfelt for people with heart failure. It helps spot early signs of worsening heart failure by checking changes in leg size, aiming to prevent hospital stays. It's for adults aged 18 and over.
For: Heart FailureUnited Kingdom - RecruitingNA
Biocollection of Patients With ANCA Associated Vasculitis
This study is collecting samples like blood and urine from people with a rare condition called ANCA-associated vasculitis. Researchers want to understand the disease better, predict future health issues, and find personalised ways to manage it, ultimately improving lives and treatments.
For: ANCA-associated VasculitisFrance - RecruitingNA
Optimizing Sleep Maternal-Offspring Bonding and Sleep in the Maternity Ward
This study looks at how different baby cribs in maternity wards affect new mums and their babies. It compares special 'co-sleeping' cribs, which allow babies to be very close, with standard cribs. The aim is to see if co-sleeping cribs improve sleep for mums and babies, and help mothers and newborns bond.
For: Co-spleeping · Spleeping Quality · NewbornFrance - Not yet recruiting
Relative Energy Deficiency in Sport and Dance
This study looks at a condition called Relative Energy Deficiency in Sport (REDs) in dancers, gymnasts, and combat sports athletes. It aims to understand how common it is and its effects, especially on bone health, to help coaches and doctors better support athletes.
For: Relative Energy Deficiency in Sport · Bone Stress ReactionUnited Kingdom - Recruiting
Prospective Evaluation of PH-impedance Tracings According to the Wingate Consensus, and Influence on GERD Classification According to the Lyon Consensus
This study looks at how we check for acid reflux (GERD) using a special test called pH-MII. We want to make sure the results are interpreted correctly, especially when computers help analyse them, to improve how we understand and treat reflux.
For: GERDBelgium · Germany - Active not recruitingPHASE3
MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial
This study compares two treatments, methotrexate and tocilizumab, for Giant Cell Arteritis (GCA). GCA causes inflammation in blood vessels, often affecting older adults. The aim is to find out if methotrexate is as effective as tocilizumab in preventing GCA flare-ups, but potentially with fewer side effects and lower cost.
For: Giant Cell ArteritisFrance - RecruitingNA
Monitoring Oedema in Heart Failure to Improve Function and Reduce Hospitalisation Risk
This study looks at a new device called Heartfelt for people with heart failure. It helps spot early signs of fluid build-up (swelling) by taking pictures of legs. We want to see if it improves life and reduces hospital stays compared to usual care.
For: Heart FailureUnited Kingdom - RecruitingNA
BREMISS : Brain Resilience Minor Stroke Study
This study, BREMISS, aims to understand why some people recover better than others after a minor stroke. Researchers hope to predict quality of life years later by looking at early patient information, including brain scans and questionnaires.
For: Stroke IschemicFrance - Enrolling by invitation
Quality of Life in Patients With Hemorrhagic Telangiectasia
This study looks at how Hereditary Hemorrhagic Telangiectasia (HHT) affects patients' quality of life, especially their feelings about their appearance. It uses questionnaires to understand the daily impact of this blood vessel condition.
For: Hereditary Hemorrhagic TelangiectasiaGermany - Not yet recruiting
Establishment of a Patient Library in Patients With Pruritus Sine Materia
This study aims to understand chronic itching better. We'll collect samples like blood and skin, and ask you to complete questionnaires to learn more about the causes of itching. This helps improve diagnosis and treatment.
For: Pruritus · Chronic Pruritus · ItchFrance - RecruitingNA
Digital Technology for Sleep and Homelessness
This study looks into using digital tools to help homeless people in Canada with their sleep problems, especially sleep apnea. It aims to diagnose and treat sleep apnea and see how this improves their quality of life, as many homeless people suffer from poor sleep.
For: Sleep Apnea · Sleep Disorder · Sleep DeprivationCanada