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To Assess the Correlation of High-resolution Specimen PET-CT Imaging, Using the XEOS AURA 10 PET-CT, With the Histopathology Results and Long-term Outcome of Patients Undergoing Resective Cancer Surgery.

This study is gathering information from patients who have had cancer surgery. Researchers are using a special type of scan, called PET-CT, on the removed cancer tissue. They want to see how well these scans match up with what doctors find when they look at the tissue under a microscope (histopathology). They also want to understand if these scan results help doctors make better decisions about treatment and if they lead to better long-term health for patients. By looking at real patient information, the study aims to learn if this new scanning technology can improve how we check removed cancer tissue and ultimately provide better care for people with cancer.

At a glance

Status
Recruiting
Sponsor
XEOS Medical
Enrolment target
850
Start
19 Nov 2025
Estimated completion
15 Jan 2031

What is this study about?

This study is looking into a new way to examine cancer tissue after it has been removed during surgery. Normally, doctors look at removed tissue very closely under a microscope to understand the cancer. This study uses a special scanning machine, called a PET-CT scanner, to take detailed pictures of the removed tissue. The researchers want to see if these new scans give similar information to what doctors find using traditional methods.

The main goal is to understand if these special scans can help doctors make more accurate decisions during and after surgery. They will compare the scan results with what was seen during surgery and what the lab tests show. The study will also track how patients do over a longer period to see if using these scans leads to better health outcomes.

By gathering all this information, the study hopes to find out if using this advanced scanning technology on removed cancer tissue can improve how we understand and treat different cancers, including prostate, breast, and head and neck cancers. This could lead to better overall care for patients in the future.

Key takeaways

  • The study uses special scans of removed cancer tissue.
  • It compares these scans with lab results and patient health outcomes.
  • The aim is to see if this scanning improves cancer diagnosis and treatment decisions.
  • Participation involves allowing researchers to use existing medical records and scan data.
  • There are no new tests, treatments, or visits required for this study.
  • The study could help improve future cancer care for patients.

Who may be eligible?

To be part of this study, you need to be an adult (18 years or older) who has had cancer surgery and your removed cancer tissue was successfully scanned using a special PET-CT machine called the AURA 10. The scan must have shown part of the main tumour and have been technically good enough to understand.

Also, you need to be willing to allow the researchers to look at your medical records. For patients already included without current follow-up, you'll simply be informed that your records are being used.

You cannot be part of this study if you were under 18 when you had your surgery, or if you are pregnant or breastfeeding.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. I am 18 years old or older.
  2. I have had surgery for cancer.
  3. My removed cancer tissue had a special PET-CT scan, and it was successful.
  4. I am willing to allow researchers to use my existing medical records.
  5. I am not pregnant or breastfeeding (if applicable).
Answer every question to see your result.

What does participation involve?

This study doesn't involve any extra visits or tests for you. It's a 'registry' study, which means researchers are collecting and looking back at information that has already been gathered from your medical records and from the special scans done on your removed cancer tissue. You won't need to take any new medication or have any additional follow-up appointments solely for this study. Your participation simply involves giving permission for your existing medical information and scan results to be used for research. There's no specific duration for your individual involvement as the data is already collected.

Potential risks and benefits

Since this study only looks at information from your medical records and already-completed tissue scans, there are no direct physical risks to you. You won't undergo any new procedures. The potential benefit is that the information gathered could help doctors better understand cancer and improve treatment decisions for future patients. You have the right to withdraw your consent for your data to be used at any time, which means your information would no longer be included in the study.

Locations (2)

  • AZ Maria Middelares
    Verified postcode
    Ghent, Belgium· Recruiting
  • University Hospitals Coventry and Warwickshire (UHCW) NHS Trust
    Verified postcode
    Coventry, United Kingdom· Recruiting

Common questions

What is a 'registry study'?

It's a type of study where researchers collect existing medical information and records, rather than asking patients to undergo new tests or treatments.

Will I have to do anything extra if I join?

No, you won't need any extra appointments, scans, or take any new medications for this study. Researchers will use information already collected from your past care.

What is PET-CT imaging in this study?

It's a special type of scan used on the cancer tissue after it has been removed during surgery, not on your body directly. It helps doctors get a detailed look at the tissue.

How will this study help patients?

By understanding if these special scans improve how doctors assess cancer tissue, it could lead to better decisions about treatment and ultimately improve care for people with cancer in the future.

Can I change my mind after agreeing to participate?

Yes, you can withdraw your consent for your information to be used in the study at any time without it affecting your medical care.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "To Assess the Correlation of High-resolution Specimen PET-CT…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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