ribonuclease H2 subunit A
Last updated 26 Sept 2024
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The RNASEH2A gene provides instructions for making one part (subunit) of a group of proteins called the RNase H2 complex. This complex is a ribonuclease, which means it is an enzyme that helps break down molecules that contain RNA, a chemical cousin of DNA. In particular, the RNase H2 complex helps break down a specific type of molecule that is made up of one strand of RNA and one strand of DNA (RNA-DNA hybrids). RNA-DNA hybrids are formed during DNA copying (replication) and are found in all cells.
Normal function
The RNASEH2A gene provides instructions for making one part (subunit) of a group of proteins called the RNase H2 complex. This complex is a ribonuclease, which means it is an enzyme that helps break down molecules that contain RNA, a chemical cousin of DNA. In particular, the RNase H2 complex helps break down a specific type of molecule that is made up of one strand of RNA and one strand of DNA (RNA-DNA hybrids). RNA-DNA hybrids are formed during DNA copying (replication) and are found in all cells.
The RNase H2 complex is also thought to be involved in DNA replication and error repair. This complex also likely plays an important role in the immune system by removing unnecessary pieces of DNA that might otherwise trigger an immune response.
Conditions referring to this gene or chromosome
Other names
ribonuclease H2, large subunit
ribonuclease H2, subunit A
ribonuclease HI large subunit
ribonuclease HI subunit A
RNase H(35)
RNase H2 subunit A
RNase HI large subunit
RNASEHI
RNH2A_HUMAN
RNHIA
RNHL
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Further reading and references
- ribonuclease H2 subunit A; MedlinePlus, National Library of Medicine.
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