Can I take Amlodipine and Cod liver oil together?
Drug interaction guide
Originally published 25 Jan 2026
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Both amlodipine and cod liver oil can lower your blood pressure. Taking them together might cause your blood pressure to drop slightly lower than intended.
Why this happens
Amlodipine is a calcium channel blocker designed to lower blood pressure. Cod liver oil contains omega-3 fatty acids, which have a natural, mild blood-pressure-lowering effect. When used together, these effects can add up.
What you should do
It is generally safe to take these together, but you should monitor your blood pressure regularly. If you feel dizzy, lightheaded, or faint (especially when standing up), speak to your doctor or pharmacist. They may need to adjust your medication dose.
Important precautions
Liver disease
Amlodipine is broken down by the liver; if your liver is not working well, the medicine can build up to dangerous levels. Your doctor may need to start you on a much lower dose.
Pregnancy
Do not take cod liver oil if you are pregnant or planning a baby. It contains high levels of Vitamin A (retinol), which can be harmful to an unborn baby's development.
Severe aortic stenosis (heart valve narrowing)
Amlodipine can cause a dangerous drop in blood pressure or reduce blood flow to the heart if you have a severely narrowed heart valve.
Food and drink warnings
Grapefruit juice
Grapefruit juice can increase the amount of amlodipine in your blood, which may cause your blood pressure to drop too low and increase the risk of side effects like headaches or swollen ankles. It is best to avoid drinking large amounts of grapefruit juice while taking this medicine.
Alcohol
While alcohol does not directly interact with amlodipine, both can lower your blood pressure. Drinking alcohol while taking amlodipine may make you feel dizzy, lightheaded, or sleepy. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you first.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
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