Can I take Amlodipine and Fibre supplements together?

Why this happens

Soluble fibre can bind to medications in the digestive tract or slow down the rate at which the stomach empties. This can interfere with how well the amlodipine is absorbed into your bloodstream.

What you should do

You do not need to stop taking fibre, but you should try to space them out. Take your amlodipine at least 2 hours before or 4 to 6 hours after taking a fibre supplement (such as psyllium husk, Fybogel, or methylcellulose). Monitor your blood pressure regularly to ensure it remains stable.

Important precautions

Dehydration/Low fluid intake

You must drink plenty of water (at least 200ml per dose) when taking fibre supplements. Without enough fluid, the fibre can swell and cause a blockage in your throat or bowel.

Grapefruit consumption

Avoid drinking large amounts of grapefruit juice. Grapefruit can significantly increase the level of amlodipine in your blood, making your blood pressure drop too low and increasing side effects.

Drug absorption interference

Fibre supplements can trap other medicines and stop them from being absorbed. Take your other medicines at least 1 hour before or 2 to 4 hours after taking a fibre supplement.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.