Can I take Alogliptin and Fibre supplements together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking fibre supplements at the same time as alogliptin may slightly lower the amount of medicine your body absorbs. This could potentially make the alogliptin less effective at controlling your blood sugar levels.
Why this happens
Fibre supplements (like psyllium husk or methylcellulose) can trap medicines in the digestive tract or slow down how quickly they are absorbed into the bloodstream.
What you should do
To ensure your medicine works correctly, try to take alogliptin at least 1 hour before or 2 to 4 hours after taking a fibre supplement. You should also monitor your blood sugar levels regularly and speak to your doctor if you notice they are consistently higher than usual.
Important precautions
Pancreatitis
Stop taking alogliptin and see a doctor immediately if you experience severe and persistent stomach pain, which may reach through to your back, as this can be a sign of an inflamed pancreas.
Medication timing
Take fibre supplements at least 2 hours before or after taking any other medicines, as they can trap other drugs and prevent your body from absorbing them properly.
Fluid intake
You must drink plenty of water (at least 200ml per dose) when taking fibre supplements; without enough fluid, the supplement can swell and cause a blockage in your throat or bowel.
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published

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