Can I take Magnesium and Flecainide together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking magnesium supplements alongside flecainide is generally safe, but very high doses of magnesium could potentially interfere with how flecainide works on your heart rhythm. In some cases, magnesium can actually be helpful for heart rhythm issues, but it must be balanced correctly.
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Why this happens
Both magnesium and flecainide affect the electrical signals and mineral channels (like sodium and potassium) in your heart cells. While they don't usually stop each other from being absorbed, having too much or too little magnesium in your blood can change how effective flecainide is at controlling your heart rhythm.
What you should do
You can usually take these together, but do not start high-dose magnesium supplements without checking with your doctor first. Your doctor may want to monitor your blood mineral levels (electrolytes) to ensure flecainide works safely and effectively. If you feel any new heart palpitations, dizziness, or shortness of breath, contact your healthcare provider.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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