Can I take Magnesium and Vitamin b complex together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no known harmful interaction between magnesium and Vitamin B complex. In fact, these two supplements are often taken together because they work well as a team in the body.
In this article:
Continue reading below
Why this happens
Magnesium and B vitamins (especially Vitamin B6) have a synergistic relationship. Vitamin B6 helps the body absorb magnesium more efficiently into the cells where it is needed. They do not compete for absorption or interfere with how the other is processed by the liver or kidneys.
What you should do
It is safe to take these together. For the best absorption, you can take them with a meal. Always stick to the recommended daily dose on the packaging, as taking very high doses of magnesium can sometimes cause diarrhoea or stomach upset.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Ibuprofen gel 10% and Shortec together?
Using ibuprofen gel alongside Shortec (oxycodone) is generally safe, but there is a small risk of increased side effects such as drowsiness, dizziness, or stomach irritation if the ibuprofen is absorbed into the bloodstream in significant amounts.

Treatment and medication
Can I take Black cohosh and Vitamin d together?
There are no known significant interactions between black cohosh and vitamin D. It is generally considered safe to take these two supplements together.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.