Latest studies
- Active not recruiting
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice
This study looks at how a cancer drug called atezolizumab works in real patients. Researchers want to see its effects and safety under normal hospital care, for different types of cancer it's approved for.
Urothelial CarcinomaNon-Small Cell Lung CancerSmall Cell Lung CancerHepatocellular CarcinomaEgypt - Recruiting
Exploring the hidden burden of living with Glanzmann thrombasthenia
This study wants to hear from people living with Glanzmann thrombasthenia (GT) and their caregivers. We want to understand the daily challenges and feelings of those affected. Your stories can help improve support and understanding for everyone with GT.
Glanzmann thrombastheniaEgypt - Recruiting
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
This study looks at how a new scoring system helps doctors decide the best treatment for broken bones in the back caused by osteoporosis. It compares how well patients do when doctors follow the score's advice versus when they choose a different path.
Osteoporotic FracturesOsteoporosisEgypt - Active not recruiting
Male Breast Cancer: Understanding the Biology for Improved Patient Care
This study looks at breast cancer in men. Researchers are gathering information and samples from men with breast cancer to better understand the disease and improve how it's treated. It's a large international effort to learn more about this rare condition.
Breast CancerEgypt - Active not recruitingPHASE3
A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
This study compares a new drug, Giredestrant, with standard hormone therapy for early breast cancer. It's for people with a specific type of breast cancer (ER-positive, HER2-negative) who have already had surgery.
Early Breast CancerEgypt - Active not recruitingPHASE2, PHASE3
Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia
This study is looking into a new medication, M281, for adults with a blood condition called warm autoimmune hemolytic anemia (wAIHA). It aims to see if the medicine is effective and safe compared to a dummy treatment. Participants will be treated for a long time, with close monitoring.
Warm Autoimmune Hemolytic AnemiaEgypt - Recruiting
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) International Registry
This international study is gathering information on a very rare blood cancer called Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN). It aims to understand the disease better, look at different treatments, and improve care by collecting data from patients worldwide.
Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)Egypt - RecruitingPHASE3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
This study looks at a new medicine, Baxdrostat, combined with an existing one, Dapagliflozin, for people with long-term kidney disease and high blood pressure. It aims to see if this combination can help protect the kidneys and heart better than Dapagliflozin alone.
Chronic Kidney Disease and HypertensionEgypt - Recruiting
Evaluation of self-initiated humour protocol
This study explores a new digital humour program called SIHP to boost your emotional well-being. It involves daily exercises and weekly lessons over eight weeks, using a virtual coach to help you laugh more and feel better.
Emotional well-beingEgypt - Active not recruiting
The OPBC-07/microNAC Study
This study looks at whether it's safe to skip a full lymph node removal surgery in breast cancer patients who have only tiny traces of cancer left in their armpit lymph nodes after chemotherapy. It checks how these patients have fared over time.
Breast CancerEgypt - Active not recruitingPHASE3
A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)
This study is testing a new tablet medicine called etavopivat for people aged 12 to 65 with sickle cell disease. It aims to see if the medicine can improve a patient's red blood cells and reduce painful sickle cell crises. Half the group will receive the new treatment, the other a placebo.
Sickle Cell DiseaseEgypt - Recruiting
Computerized Registry of Patients With Venous Thromboembolism (RIETE)
The RIETE study is building a large database of information from patients with blood clots (venous thromboembolism). It helps doctors better understand and treat patients, especially those with other health problems, to improve care and understand what medicine works best for different groups.
Venous ThromboembolismEgypt - RecruitingNA
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
This study looks at different ways of giving blood transfusions to younger patients (under 66) having heart surgery. It compares two common approaches to see which one is safer and more effective. The goal is to improve care for people undergoing these operations.
DisorderHeartPostoperativeCardiac SurgeryEgypt - Recruiting
Advancing Knowledge in Ischemic Stroke Patients on Oral Anticoagulants
This study looks at people who have a stroke while taking blood thinners for an irregular heartbeat. It aims to understand why this happens and what treatments work best afterwards to prevent another stroke. Researchers will collect information from medical records and follow some patients over time.
Ischemic StrokeOral AnticoagulationAtrial Fibrillation (AF)Outcome AssessmentEgypt - RecruitingPHASE3
Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen
This study looks at a new medicine called Tozorakimab. We want to see if it can help people in hospital with lung infections who need extra oxygen. The goal is to stop them from getting sicker, like needing a breathing machine, or even dying.
Viral Lung Infection and Acute Respiratory FailureEgypt - Active not recruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)
This study looks at a new drug, Giredestrant, combined with an existing treatment called Phesgo, for advanced breast cancer. It aims to see if this new combination is safe and works better than Phesgo alone for people with specific types of breast cancer.
Locally Advanced or Metastatic Breast CancerEgypt - Recruiting
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry
This study tracks the health of people with Gaucher disease over time, whether or not they are receiving treatment. There's also a sub-study for pregnant women with Gaucher disease to see how their pregnancies and babies' health progress. It helps doctors learn more about the condition.
Gaucher DiseaseCerebroside Lipidosis SyndromeGlucocerebrosidase Deficiency DiseaseGlucosylceramide Beta-Glucosidase Deficiency DiseaseEgypt - Recruiting
International Prospective REgistry on Pre-pectorAl Breast REconstruction
This study looks at how well a type of breast reconstruction works after breast cancer surgery. It's for women who have reconstruction using implants placed above the chest muscle. Doctors are collecting information on surgery, appearance, cancer results, and quality of life.
Breast CancerEgypt - Active not recruiting
A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
This study looks at how well certain eye medicines from Roche work for conditions like wet macular degeneration and diabetic eye disease in real patients. It's about understanding long-term results and why doctors choose specific treatments, without changing how patients are usually cared for.
Neovascular Age-related Macular DegenerationDiabetic Macular EdemaRetinal Vein OcclusionBranch Retinal Vein OcclusionEgypt - RecruitingPHASE3
A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia
This study is testing a new medicine, Etavopivat, for sickle cell disease and thalassaemia. It looks at how safe and effective the treatment is over a long period for people already benefiting from it in previous studies. The goal is to improve oxygen delivery in the body.
Sickle Cell DiseaseThalassemiaEgypt - Active not recruitingPHASE3
RT or No RT Following Chemotherapy in Treating Patients With Stage III/IV Hodgkin's Disease
This study looks at whether adding radiation after chemotherapy helps people with advanced Hodgkin's disease. Researchers want to see if this combination prevents the disease from coming back or helps people live longer, compared to chemotherapy alone.
LymphomaEgypt - Active not recruitingPHASE3
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
This study is for children and young people under 25 with a type of brain tumour called low-grade glioma. It compares a new medicine, tovorafenib, with standard chemotherapy to see which works best and is safest for those needing first-time treatment.
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade GliomaEgypt - Active not recruitingPHASE4
EdoxabaN foR IntraCranial Hemorrhage Survivors With Atrial Fibrillation (ENRICH-AF)
This study looks at whether a blood-thinning medicine called edoxaban can reduce the risk of stroke in people with an irregular heartbeat (atrial fibrillation) who have previously had bleeding in the brain. It compares edoxaban to not taking blood thinners.
Intracranial HemorrhagesAtrial FibrillationEgypt - Active not recruitingPHASE3
A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn's Disease
This study looks at a new medicine called risankizumab for Crohn's disease. We're checking how well it works and if it's safe for people who have already started treatment. It's like a follow-up to see how different doses work and how people feel over time.
Crohn's DiseaseEgypt - Active not recruitingPHASE3
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
This study looks at new drug combinations for advanced liver cancer that has already been treated. It compares atezolizumab with lenvatinib or sorafenib against lenvatinib or sorafenib alone, to see if the combinations work better and are safe.
Unresectable Hepatocellular CarcinomaEgypt - Recruiting
Security and effectiveness assessment of locking systems in ventriculostomy for traumatic brain injury
This study looks at new ways to treat serious head injuries by comparing two methods for draining fluid from the brain. It aims to make a procedure called ventriculostomy safer and more effective, especially for preventing complications like infections or the drain moving out of place.
Intracranial compartment syndrome in traumatic brain injury patientsEgypt - Active not recruitingPHASE3
Long-term Safety and Efficacy Extension Trial of Bimatoprost SR
This study looks at the long-term effects of a special eye implant, Bimatoprost SR, for people with glaucoma or high eye pressure. It checks how safe and effective it is over a longer period, continuing from previous studies.
Open-Angle GlaucomaOcular HypertensionEgypt - Active not recruitingPHASE3
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
This study looks at a medicine called ocrelizumab for people with progressive multiple sclerosis (PMS). It aims to see how well it works and if it's safe. Everyone in the study will receive the medicine, and doctors will watch their progress closely.
Progressive Multiple Sclerosis (PMS)Egypt - Active not recruitingPHASE3
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433
This study looks at a new medicine called upadacitinib for adults with Crohn's disease. It checks how well it works and if it's safe over a long time for people who have already started treatment in previous studies. The aim is to see if it can help manage Crohn's.
Crohn's DiseaseEgypt - Active not recruitingPHASE3
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
This study looks at how well a medicine called risankizumab works and how safe it is for people with ulcerative colitis. It's for those who have already shown improvement with this medicine in a previous study.
Ulcerative Colitis (UC)Egypt - Active not recruitingPHASE3
Assess Efficacy and Safety of Durvalumab Alone or Combined With Bevacizumab in High Risk of Recurrence HCC Patients After Curative Treatment
This study is testing new treatments for liver cancer (hepatocellular carcinoma) in people who have had their cancer removed but are at high risk of it coming back. It compares a drug called durvalumab, alone or with bevacizumab, against a dummy treatment (placebo) to see if they can prevent the cancer from returning.
Hepatocellular CarcinomaEgypt - Recruiting
AutoInflammatory Disease Alliance Registry (AIDA)
This project is building a secure online registry to collect health information from people with rare inflammatory conditions. The goal is to better understand these diseases, how they affect people, and how different treatments work. Your information could help doctors improve care for others.
Hereditary Autoinflammatory DiseasesSchnitzler SyndromeBehcet SyndromePFAPA SyndromeEgypt - Recruiting
The K-Map Study, Global Prevalence of KC
The K-Map Study is looking for young people aged 6-23 to help understand how common a condition called keratoconus is. It uses a special camera to check eyes, even if they seem healthy, to see if more people have this eye problem than we currently think.
KeratoconusEgypt - Active not recruitingPHASE3
A Study Comparing Adjuvant Alectinib Versus Adjuvant Platinum-Based Chemotherapy in Patients With ALK Positive Non-Small Cell Lung Cancer
This study compares a new drug, alectinib, with standard chemotherapy for people with a certain type of lung cancer (ALK-positive non-small cell lung cancer) after surgery. We want to see if alectinib is better at stopping the cancer from coming back and if it's safe.
Carcinoma, Non-Small-Cell LungEgypt - Active not recruitingPHASE3
A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease
This study is testing a new medication called guselkumab for people with Crohn's disease who have problems with fistulas around the back passage. It aims to see how well the medication works and if it's safe compared to a dummy treatment.
Fistulizing Crohns DiseasePerianal Crohns DiseaseEgypt