Latest studies
- RecruitingPHASE3
An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC
This study is looking at new treatments for a type of bladder cancer that has a high chance of coming back after surgery. It compares two new drugs, Dato-DXd and Rilvegostomig, with standard treatments to see if they are safer and more effective.
High-risk Muscle Invasive Urothelial CarcinomaSouth Korea - RecruitingPHASE1
A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer
This study looks at a new medicine, PF-08052667, for a type of bladder cancer that hasn't spread into the muscle. It checks if the medicine works alone or with other treatments like BCG and sasanlimab, especially for cancer that has come back.
Non-muscle Invasive Bladder CancerSouth Korea - Recruiting
A Study to Identify Breast Cancer (IDBC)
This study is testing a new blood test called Syantra DX Breast Cancer. It aims to find out if this test can accurately detect breast cancer early. Researchers hope it could one day help women who have had an abnormal mammogram or are being screened for breast cancer, making diagnosis quicker and easier.
Breast Cancer FemaleSouth Korea - Not yet recruitingPHASE3
A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
This study is looking at a new medication called Brenipatide for adults with major depression. It aims to see if this new treatment, when added to usual care, can help prevent depression symptoms from coming back compared to a dummy treatment (placebo) plus usual care.
Depressive Disorder, MajorSouth Korea - RecruitingPHASE3
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
This study is for people who have already taken part in a trial for the medicine Benralizumab (Fasenra) for asthma, EGPA, or HES. If the medicine helped them, this study offers a way to continue receiving it while doctors monitor their health and the medicine's long-term effects.
AsthmaEosinophilic Granulomatosis With Polyangiitis (EGPA)Hypereosinophilic Syndrome (HES)South Korea - RecruitingPHASE2
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
This study is for people with a type of bladder cancer that has grown into the bladder muscle. Doctors are looking at a new treatment with two medicines, Enfortumab Vedotin and Pembrolizumab, to see if it can help people keep their bladder instead of having surgery to remove it.
Muscle-invasive Bladder CancerSouth Korea - RecruitingPHASE3
A Clinical Study of Belzutifan (MK-6482) and Zanzalintinib in People With Renal Cell Carcinoma (RCC) (LITESPARK-034/LS-034/MK-6482-034)
This study is testing if combining two targeted therapies, belzutifan and zanzalintinib, works better than belzutifan alone for advanced kidney cancer. Researchers want to see if this combination helps people live longer and keeps the cancer from getting worse.
Carcinoma, Renal CellSouth Korea - RecruitingPHASE2
A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)
This study is testing a new medicine called MK-8690 for people with moderate to severe ulcerative colitis. Researchers want to see if it's better than a dummy medicine (placebo) at helping people feel better and achieve remission.
Colitis UlcerativeUlcerative ColitisSouth Korea - RecruitingPHASE3
A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)
This study is looking at new ways to treat advanced lung cancer (squamous non-small cell lung cancer) that has spread. It compares two different drug combinations, including a new medicine called rilvegostomig, to see if they can help patients live longer and improve their quality of life.
Non-small Cell Lung CancerSouth Korea - Active not recruitingPHASE3
A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer
This study looks at adding a drug called ribociclib to standard hormone therapy for people with early-stage breast cancer. It aims to see if this combination works better at preventing cancer from coming back and if it's safe for patients.
Early Breast CancerSouth Korea - RecruitingPHASE3
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
This study is for people with early-stage lung cancer (NSCLC) that's been removed by surgery but has a high chance of coming back. Researchers want to see if new medicines, Intismeran and Pembrolizumab, can help stop the cancer from returning, compared to a dummy drug.
Non-small Cell Lung CancerSouth Korea - RecruitingPHASE3
A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are High Risk (MK-4482-023)
This study is testing a new medicine, Molnupiravir, to see if it can stop people at high risk of severe COVID-19 from becoming very ill. It's for people who can't take other COVID-19 treatments. We want to find out if it works better than a dummy treatment.
Coronavirus Disease (COVID-19)South Korea - Enrolling by invitationPHASE3
Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP
This study looks at the long-term safety and effectiveness of a treatment called riliprubart for adults with a nerve condition called CIDP. It's for people who have already been in other riliprubart studies and want to continue treatment.
Polyneuropathy, Inflammatory Demyelinating, ChronicSouth Korea - RecruitingPHASE3
A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata
This study is looking at two different strengths (50mg and 100mg) of a medicine called ritlecitinib for people aged 12 and over with alopecia areata. It aims to understand how safe and effective the 100mg dose is for hair regrowth.
Alopecia AreataSouth Korea - Active not recruitingPHASE1, PHASE2
Study of LEE011, BYL719 and Letrozole in Advanced ER+ Breast Cancer
This study looks at new drug combinations for advanced ER+ breast cancer in women aged 18-100. It tests LEE011 and BYL719 with letrozole to find safe and effective doses, hoping to improve treatment for this type of cancer.
Breast CancerSouth Korea - RecruitingPHASE3
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
This study looks at a new medicine called survodutide for adults with a liver condition called NASH or MASH and scarring (cirrhosis). Participants will get either the medicine or a dummy treatment, along with diet and exercise advice, to see if it helps their liver.
Metabolic Dysfunction Associated SteatohepatitisSouth Korea - Recruiting
Product Surveillance Registry
This study keeps track of how well Medtronic medical devices, like those for heart problems or other conditions, work in real life. It aims to make sure these devices are safe and effective for patients.
Cardiac Rhythm DisordersUrological DisordersNeurological DisordersCardiovascular DisordersSouth Korea - RecruitingPHASE2, PHASE3
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
This study keeps an eye on people who have had a special treatment called gene-modified T-cell therapy for cancer. It aims to check their health and how well the treatment worked over a long time, making sure it's safe and effective.
NeoplasmsSouth Korea - Active not recruitingPHASE3
Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)
This study looks at a new drug, pembrolizumab, combined with standard chemotherapy after surgery for certain types of womb cancer (endometrial cancer). We want to see if this combination helps stop the cancer from coming back and helps people live longer compared to chemotherapy alone.
Endometrial NeoplasmsSouth Korea - Active not recruitingPHASE2
A Study to Learn About How Well BAY 3401016 Works in Adults With Alport Syndrome
This study is looking into a new medication called BAY 3401016 for adults with Alport Syndrome, a genetic kidney condition. It aims to see if this medicine can help slow down kidney damage by blocking a specific protein.
Alport SyndromeSouth Korea - RecruitingPHASE3
A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia
This study is testing a new medicine, mezagitamab, for adults with a bleeding condition called ITP. We want to see if it helps keep platelet counts stable. It's given by injection under the skin.
Immune Thrombocytopenic Purpura (ITP)South Korea - RecruitingPHASE3
A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
This study is looking at a new drug, Saruparib, for men with high-risk prostate cancer and a faulty BRCA gene. It aims to see if adding Saruparib to standard treatments can help prevent the cancer from spreading.
Prostate CancerSouth Korea - RecruitingPHASE3
The AIRTIVITY™ Study: A Study to Find Out Whether BI 1291583 Helps People With Bronchiectasis
This study is looking into a new medicine, BI 1291583, for people with bronchiectasis. It aims to see if this medicine can help reduce flare-ups, which are common with the condition. Participants will take a tablet daily and be monitored for up to 1 year and 8 months.
BronchiectasisSouth Korea - RecruitingPHASE3
A Study to Compare Elritercept With Epoetin Alfa to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions
This study compares Elritercept with Epoetin Alfa for adults with a certain type of Myelodysplastic Syndrome (MDS) and anaemia. It checks if Elritercept reduces the need for blood transfusions and improves tiredness, while also looking at safety.
Myelodysplastic SyndromeAnemiaSouth Korea - RecruitingPHASE1
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
This study is testing a new drug, VVD-133214, for advanced solid tumours, including a type of bowel cancer. It looks at safety, how the body handles the drug, and if it can help shrink tumours. It's an early-stage study, sometimes testing the new drug with other standard treatments.
Advanced Solid TumorsColorectal CancerSouth Korea - RecruitingPHASE3
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
This study looks at a new treatment called intismeran autogene, given with pembrolizumab, after surgery for non-small cell lung cancer. We want to see if this combination stops the cancer from coming back compared to pembrolizumab alone.
Carcinoma, Non-Small-Cell LungSouth Korea - RecruitingPHASE2, PHASE3
Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)
This study is testing a new medicine, povetacicept, for people with a kidney condition called primary membranous nephropathy (pMN). It aims to see how well it works, if it's safe, and if people can tolerate it compared to another treatment, tacrolimus.
Primary Membranous NephropathySouth Korea - RecruitingPHASE3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
This study looks at a new medicine called zilebesiran for people with high blood pressure that isn't well controlled, especially if they also have heart problems or are at high risk of developing them. The aim is to see if zilebesiran can reduce serious heart-related events like heart attacks or strokes.
High Risk Cardiovascular DiseaseHypertensionHigh Cardiovascular RiskSouth Korea - RecruitingPHASE3
A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
This study compares a new medicine, opevesostat, with existing treatments like abiraterone or enzalutamide for prostate cancer that has spread and is no longer responding well to standard hormone therapy. It aims to see if opevesostat is safer and more effective at stopping cancer growth.
Metastatic Castration-resistant Prostate Cancer (mCRPC)Prostatic NeoplasmsSouth Korea - RecruitingPHASE1, PHASE2
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
This study is testing a new drug, Zilovertamab Vedotin, for children and young adults aged 6 months to 25 years with certain blood cancers (like some types of leukaemia and lymphoma) and solid tumours (like neuroblastoma and Ewing sarcoma) that have come back or not responded to previous treatments.
B-cell Acute Lymphoblastic LeukemiaDiffuse Large B-cell LymphomaBurkitt LymphomaNeuroblastomaSouth Korea - RecruitingPHASE3
Low INR to Minimize Bleeding With Mechanical Valves Trial
This study is looking at whether taking a lower dose of a blood thinner called warfarin is safer for people with a mechanical heart valve in their main artery. We want to see if this lower dose can prevent serious bleeding without increasing the risk of blood clots or stroke.
Bleeding Post-mechanical Valve ReplacementThromboembolism Post-mechanical Valve ReplacementSouth Korea - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
This study is testing a new medication called Tulisokibart for people with moderate to severe Crohn's disease. Researchers want to see if it's safe and effective in reducing symptoms and improving the gut lining. It involves different ways of giving the medicine compared to a dummy treatment.
Crohn's DiseaseSouth Korea - RecruitingPHASE3
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
This study looks at the long-term safety and effectiveness of a cancer drug called pembrolizumab (and related treatments) for people with advanced cancers. It's for patients who are already receiving these treatments in other studies and want to continue.
Solid TumorsHematologic MalignanciesSouth Korea - RecruitingPHASE2
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
This study is looking at a new treatment called HER3-DXd for people with certain advanced solid tumours that haven't responded to other treatments. It aims to see how well it works and if it's safe for different types of cancer, like melanoma, lung cancer, and breast cancer.
Advanced Solid TumorMelanomaHead and Neck CancerGastric CancerSouth Korea - RecruitingPHASE3
LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
This study looks at a new medicine called survodutide for adults with a liver condition called MASH and moderate to advanced liver damage. It aims to see if the medicine can improve liver health and how safe it is.
Metabolic Dysfunction Associated Steatohepatitis (MASH)Liver FibrosisSouth Korea - RecruitingPHASE3
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
This study is for adults with a certain type of lung cancer (Stage II-IIIB non-small cell lung cancer) that has a specific genetic change (HER2 mutation) and has been fully removed by surgery. It compares a new daily tablet called zongertinib with standard treatments to see if it can stop the cancer from coming back.
Non-small Cell Lung CancerSouth Korea - RecruitingPHASE2, PHASE3
A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)
This study is testing a new medicine, zilovertamab vedotin (ZV), combined with standard treatments for a type of lymphoma called diffuse large B-cell lymphoma (DLBCL). It's for people whose lymphoma has come back or hasn't responded to previous treatments.
DLBCLDiffuse Large B-Cell LymphomaSouth Korea - RecruitingPHASE1, PHASE2
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
This study is looking for new ways to treat specific childhood cancers that have come back or not responded to previous treatments. It investigates a new medicine called HER3-DXd (also known as patritumab deruxtecan) for safety and effectiveness in children aged 1 month to 17 years with hepatoblastoma or rhabdomyosarcoma.
Malignant NeoplasmSouth Korea - RecruitingPHASE3
A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP
This study compares a new medicine, empasiprubart, with standard IVIg treatment for adults with CIDP. It looks at how well they work and if they are safe. Participants will receive one of these treatments, or a dummy treatment, for several months.
Chronic Inflammatory Demyelinating PolyneuropathyCIDPCIDP - Chronic Inflammatory Demyelinating PolyneuropathySouth Korea - RecruitingPHASE3
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
This study looks at a new drug combination, sacituzumab tirumotecan and pembrolizumab, for a type of breast cancer called triple-negative. It's for patients who had initial treatment but still have some cancer cells after surgery. We want to see if this new combination helps prevent the cancer from coming back better than standard care.
Triple-Negative Breast CancerSouth Korea - Active not recruitingPHASE3
A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
This study compares two treatments, Iberdomide and Lenalidomide, after a stem cell transplant for multiple myeloma. It aims to find out which one works better at keeping the cancer under control following initial treatment.
Multiple MyelomaSouth Korea - RecruitingPHASE3
Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)
This study is looking at a new combination of treatments for advanced lung cancer. It compares giving two drugs together (sacituzumab tirumotecan and pembrolizumab) against giving pembrolizumab on its own, to see if the combination helps people live longer.
Non-small Cell Lung Cancer (NSCLC)South Korea - RecruitingPHASE3
A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)
This study is for women with advanced ovarian cancer that has responded well to initial treatment. It's testing a new medicine called sac-TMT, sometimes with bevacizumab, to see if it can keep the cancer from growing or coming back for longer than standard care.
Ovarian NeoplasmsOvarian CancerSouth Korea - RecruitingPHASE3
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
This study looks at a new medicine, BI 690517, combined with empagliflozin, for adults with chronic kidney disease. It aims to see if this combination can help slow down kidney disease progression and protect the heart, for people with and without type 2 diabetes.
Kidney Disease, ChronicSouth Korea - RecruitingPHASE1, PHASE2
A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)
This study is testing new treatments, alone or in combination, for advanced prostate cancer that has spread and no longer responds to hormone therapy. Researchers want to see if these treatments are safe and effective in helping men with this condition.
Castration-Resistant Prostatic CancerMetastasisSouth Korea - RecruitingPHASE3
A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
This study is looking at a medicine called risankizumab for children and young people with ulcerative colitis (UC). It aims to see how well and safely it works, and how it moves through the body, for those aged 2 to 17 with moderate to severe UC.
Ulcerative ColitisSouth Korea - RecruitingPHASE3
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
This study is testing a new medicine, nerandomilast, for people with systemic sclerosis. It aims to see if the medicine can improve symptoms and slow the disease. Adults with systemic sclerosis might be able to join this study.
Systemic SclerosisSouth Korea - Active not recruitingPHASE2, PHASE3
A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
This study investigates an injection called litifilimab for adults with active lupus that mainly affects the skin, known as cutaneous lupus erythematosus (CLE). Researchers want to see if it helps reduce skin symptoms and is safe, especially for those whose current treatments aren't working well.
Subacute Cutaneous Lupus ErythematosusChronic Cutaneous Lupus ErythematosusSouth Korea - Active not recruitingPHASE2
Phase 2b Study of GSK4532990 in Adults With NASH
This study is testing a new medicine, GSK4532990, for people with a serious liver condition called Non-Alcoholic Steatohepatitis (NASH). We want to see if this medicine can improve liver damage and inflammation compared to a dummy medicine.
Nonalcoholic Fatty Liver DiseaseNon-alcoholic Fatty Liver DiseaseSouth Korea - Active not recruitingPHASE3
Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)
This study is looking at a new medicine called fenebrutinib for people with a type of multiple sclerosis (MS) called relapsing MS. It compares fenebrutinib to an existing medicine, teriflunomide, to see if it works better and is safe.
Relapsing Multiple SclerosisSouth Korea