Can I take Amlodipine and Nustendi together?

Why this happens

Amlodipine can slightly interfere with the way the body processes bempedoic acid (a component of Nustendi), leading to higher levels of the medication staying in your system for longer.

What you should do

It is generally safe to take these together, but your doctor should be aware. They may want to monitor your uric acid levels more closely or check for any signs of muscle or tendon pain. If you experience any unusual joint pain or swelling, contact your doctor.

Important precautions

Pregnancy

You must not take Nustendi if you are pregnant or breastfeeding. If you are a woman who could become pregnant, you must use effective contraception while taking it. Stop taking it immediately and tell your doctor if you become pregnant.

Gout

Nustendi can increase the levels of uric acid in your blood, which may cause gout. Tell your doctor if you have ever had gout or if you develop painful, swollen joints.

Food and drink warnings

Grapefruit and grapefruit juice

Grapefruit can increase the amount of amlodipine in your blood, which may cause your blood pressure to drop too low and increase the risk of side effects like headaches or swollen ankles. Avoid consuming large amounts of grapefruit or its juice while taking this medicine.

Alcohol

While there is no direct interaction, alcohol can lower your blood pressure. Combining it with amlodipine may make you feel dizzy or lightheaded. Additionally, both Nustendi and heavy alcohol use can affect your liver; it is best to keep your intake within the recommended limits (14 units per week).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.