Can I take Aspirin and Evolocumab together?

Why this happens

Aspirin works by preventing blood cells (platelets) from sticking together to form clots. Evolocumab is a monoclonal antibody that helps the liver remove LDL ('bad') cholesterol from the blood. Because they work through entirely different pathways in the body and are processed by different organs, they do not interfere with each other's effectiveness or safety.

What you should do

You can continue taking both medications as prescribed by your doctor. No special precautions or dose adjustments are usually necessary when using these two drugs together. Always inform your healthcare provider of all medications and supplements you are taking.

Important precautions

Asthma

Do not take aspirin if you have a history of asthma triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), as it can cause a severe, life-threatening allergic reaction or asthma attack.

Children under 16 years old

Never give aspirin to children or teenagers under 16 unless specifically prescribed by a doctor. It can cause Reye’s syndrome, a rare but very serious condition that causes swelling in the liver and brain.

Latex allergy - evolocumab

The needle cover of the pre-filled pen/syringe contains dry natural rubber (a derivative of latex), which may cause severe allergic reactions in people with a sensitive latex allergy.

Food and drink warnings

Alcohol

Drinking alcohol while taking aspirin can increase the risk of stomach irritation and bleeding. It is best to limit alcohol consumption, especially if you are taking aspirin regularly.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.