Can I take Aspirin and Evolocumab together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There are no known significant interactions between aspirin and evolocumab (Repatha). It is generally considered safe to take these two medications together.
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Why this happens
Aspirin works by preventing blood cells (platelets) from sticking together to form clots. Evolocumab is a monoclonal antibody that helps the liver remove LDL ('bad') cholesterol from the blood. Because they work through entirely different pathways in the body and are processed by different organs, they do not interfere with each other's effectiveness or safety.
What you should do
You can continue taking both medications as prescribed by your doctor. No special precautions or dose adjustments are usually necessary when using these two drugs together. Always inform your healthcare provider of all medications and supplements you are taking.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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