Latest studies
- Active not recruitingPHASE3
A Study To Assess Adverse Events and Effectiveness of Upadacitinib Oral Tablets in Adult and Adolescent Participants With Vitiligo
This study looks into a new tablet medicine, upadacitinib, for adults and teenagers with a type of vitiligo. Researchers want to see how safe it is and how well it helps improve skin when compared to a dummy pill or light therapy.
VitiligoHungary - RecruitingPHASE3
A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
This study is looking at a new treatment (BNT323) for women with advanced womb cancer that has come back. It compares BNT323 to standard chemotherapy to see if it works better at shrinking tumours and keeping the cancer from growing.
Endometrial CancerHungary - Active not recruitingPHASE3
Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
This study is for men with a certain type of advanced prostate cancer (mCSPC) that has spread and has specific gene changes. It compares a new drug called talazoparib, given with standard treatment enzalutamide, against enzalutamide alone, to see if it's safe and effective.
Prostate CancerHungary - Active not recruitingPHASE3
A Study to Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve
This study compares a new medicine, luspatercept, with a standard one, epoetin alfa, for people with a type of blood disorder called myelodysplastic syndromes (MDS). It aims to see if luspatercept can reduce the need for blood transfusions.
Myelodysplastic SyndromesHungary - RecruitingPHASE3
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)
This study looks at a new drug called anifrolumab for adults with muscle conditions like polymyositis or dermatomyositis. Researchers want to see if it's safe and helps improve symptoms when added to their usual treatment.
Polymyositis, DermatomyositisHungary - Active not recruiting
Real World Data Collection in Subjects Treated With the FARAPULSE Pulsed Field Ablation System
This study looks at how safe and effective a new treatment called FARAPULSE is for atrial fibrillation. It collects real-world information about people treated with this system in hospitals to see how well it works and if it improves their quality of life.
Atrial FibrillationHungary - RecruitingPHASE2
A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL
This study looks at a new medicine, Inotuzumab Ozogamicin (InO), for children aged 1 to 17 with a type of blood cancer called Acute Lymphoblastic Leukaemia (ALL) that has come back. It compares InO to a standard treatment to see which works better and is safer.
ACUTE LYMPHOBLASTIC LEUKEMIAHungary - RecruitingPHASE3
Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).
This study looks at the long-term safety of a new medicine, ianalumab, for people with lupus. It's for those who have already been in an earlier ianalumab study and continues to check how safe and well the medicine is tolerated over time.
Systemic Lupus ErythematosusHungary - Active not recruitingNA
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
This study aims to understand if temporarily stopping hormone therapy for early breast cancer to allow for pregnancy is safe. It will also look at fertility and emotional well-being for young women.
Early Breast CancerHungary - RecruitingPHASE3
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
This study is testing a new eye treatment, EYP-1901, against an existing one, Aflibercept, for people with diabetic macular edema (DME). It aims to see if the new treatment works just as well to improve or keep vision stable.
Diabetic Macular EdemaDMEDiabetic Macular Edema (DME)Hungary - RecruitingPHASE3
To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL
This study looks at new drug combinations (Bel-CHOP or Fol-COP) for a type of blood cancer called Peripheral T-Cell Lymphoma, which hasn't been treated before. It aims to see if these new combinations work better than the standard treatment (CHOP) and are safe.
Peripheral T Cell LymphomaHungary - Active not recruitingPHASE1, PHASE2
A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100)
This study is testing a new medicine called sotorasib for people with specific advanced cancers carrying a KRAS p.G12C gene change. Researchers want to see if it's safe, how much to give, and if it helps shrink tumours. It's an early-stage trial looking for better cancer treatments.
KRAS p.G12C Mutant Advanced Solid TumorsHungary - Active not recruitingPHASE4
A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
This study looks at how a medicine called emicizumab affects the overall health, activity levels, and joints of people with moderate or severe haemophilia A. It's for those already receiving another treatment and planning to switch to emicizumab.
Severe Hemophilia AModerate Hemophilia AHungary - Active not recruitingPHASE3
A Study of DB-1303/BNT323 vs Investigator's Choice Chemotherapy in HER2-Low, Hormone Receptor Positive Metastatic Breast Cancer (DYNASTY-Breast02)
This study looks at a new drug, DB-1303/BNT323, for advanced breast cancer that's 'HER2-low' and hormone-positive. It compares the new drug to standard chemotherapy to see if it can stop the cancer from growing for longer.
Metastatic Breast CancerHungary - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Multicenter Open-label Extension Study to Evaluate the Long-term Safety of Cenobamate Adjunctive Therapy in Subjects with Primary Generalized Tonic-Clonic Seizures
This study is looking at the long-term safety of a medicine called cenobamate for adults who have a certain type of seizure called primary generalized tonic-clonic seizures. It's an extension of a previous study, continuing to check how safe the medicine is over time.
Primary Generalized Tonic-Clonic SeizuresHungary - Active not recruitingPHASE3
Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy
This study looks at new drug combinations for advanced liver cancer that hasn't been treated before. It compares cabozantinib with atezolizumab against a standard treatment, sorafenib, to see which works better and is safer.
Hepatocellular CarcinomaHungary - Active not recruitingPHASE3
ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions
This study looks at a new medicine called Luspatercept for adults with a certain type of blood disorder (MDS) who have anaemia but don't yet need blood transfusions. It compares Luspatercept to another common medicine, Epoetin Alfa, to see which is better and safer.
Myelodysplastic SyndromesHungary - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A PHASE 3, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF ORAL OZANIMOD AS MAINTENANCE THERAPY FOR MODERATELY TO SEVERELY ACTIVE CROHN’S DISEASE
This study is looking into a new medication called Ozanimod for people with moderately to severely active Crohn's disease. Researchers want to see if it can help keep symptoms under control and reduce inflammation in the gut over time.
Moderately to Severely Active Crohn's DiseaseHungary - Active not recruitingPHASE3
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
This study looks at a new medicine called CagriSema to see how well it lowers blood sugar and helps with weight loss in people with type 2 diabetes. It's compared to another medicine called tirzepatide. Participants will get one of the medicines by chance.
Diabetes Mellitus, Type 2Hungary - Ongoing, recruitingTherapeutic exploratory (Phase II)
A 52-week, Phase 2, Open-label Trial to Evaluate the Long-term Safety and Tolerability of CVL-231 in Adult Participants With Schizophrenia
This study is looking at a new medicine called Emraclidine for adults with schizophrenia over 52 weeks. It aims to see if the medicine is safe and if people can take it for a long time without too many problems.
SchizophreniaHungary - RecruitingPHASE3
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
This study looks at a new drug, zilovertamab vedotin, combined with standard treatment for a type of blood cancer called diffuse large B-cell lymphoma (DLBCL). Researchers want to see if this new combination helps people live longer without their cancer growing or spreading, compared to standard treatment alone.
Diffuse Large B-Cell LymphomaHungary - RecruitingPHASE2
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
This study is testing a new medicine, AZD6793, for people with moderate to very severe COPD. It will compare different doses of the medicine against a dummy pill to see if it helps and is safe.
Chronic Obstructive Pulmonary Disease (COPD)Hungary - RecruitingPHASE3
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
This study looks at a new drug, calderasib, for advanced bowel cancer with a specific genetic change (KRAS G12C). Researchers want to see if adding calderasib to standard treatments helps people live longer without their cancer growing.
Colon AdenocarcinomaRectal AdenocarcinomaHungary - RecruitingPHASE2
A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
This study is testing a new medicine, FWY003, for an eye condition called Geographic Atrophy (GA), which is a severe form of Age-related Macular Degeneration (AMD). We want to see how well different doses of FWY003 work and if they are safe compared to a dummy medicine (placebo).
Geographic Atrophy Secondary to Age-related Macular DegenerationHungary - RecruitingPHASE3
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
This study is looking at a new medicine called Elecoglipron for people with certain types of heart failure. It compares Elecoglipron to a dummy medicine (placebo) to see if it helps improve heart health outcomes for adults already taking other heart failure medications, including dapagliflozin.
Heart Failure With Preserved Ejection Fraction (HFpEF)Heart Failure With Mildly Reduced Ejection Fraction (HFmrEF)Hungary - RecruitingPHASE3
A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)
This study is testing new treatments for a type of lung cancer called non-small cell lung cancer. Researchers want to see if a combination of two medicines, calderasib and pembrolizumab, works better than pembrolizumab with chemotherapy to slow down cancer growth.
Non-small Cell Lung CancerHungary - RecruitingPHASE3
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
This study compares a new medicine, Elecoglipron, to an existing one, Semaglutide, for adults with Type 2 Diabetes. It aims to see if the new drug is safe and effective for people whose diabetes isn't well-controlled and who have a higher risk of heart problems.
Type 2 Diabetes MellitusHungary - RecruitingPHASE3
A Clinical Study to Evaluate the Effects of NXT007 Compared to Factor VIII Prophylaxis in Participants With Hemophilia A
This study compares a new medicine, NXT007, with standard Factor VIII treatment for people with haemophilia A. It aims to see if NXT007 is safe and works well to prevent bleeding in adults and teenagers aged 12 and older.
Hemophilia AHungary - RecruitingPHASE3
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
This study looks at a new medicine called elecoglipron for people with long-term kidney disease. We want to see if it helps improve health compared to a dummy pill (placebo). Participants will also be taking existing kidney disease treatments like dapagliflozin. It's a large study, involving many people to get clear results.
Chronic Kidney DiseaseHungary - RecruitingPHASE3
A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma
This study looks at a medicine called IGI to see if it can help prevent infections in adults with a type of blood cancer called multiple myeloma. Participants will either get IGI for a year or only if they develop a serious infection.
Multiple MyelomaSecondary ImmunodeficiencyHungary - RecruitingPHASE3
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
This study looks at a medicine called tulisokibart for Crohn's disease and ulcerative colitis. It's for people who were in earlier trials and found benefit from it. The aim is to check its long-term safety and how well it works over time.
Crohn DiseaseColitis, UlcerativeHungary - RecruitingPHASE3
Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2
This study is testing new combinations of medicines (sonesitatug vedotin, rilvegostomig, and capecitabine) for advanced stomach, gastroesophageal junction, or oesophageal cancers. It aims to see how well they work and if they are safe for people whose cancer has a specific marker called Claudin18.2.
Gastric CancerGastroesophageal Junction AdenocarcinomaEsophageal CancerHungary - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
This study is testing a new medication called Tulisokibart for people with moderate to severe Crohn's disease. Researchers want to see if it's safe and effective in reducing symptoms and improving the gut lining. It involves different ways of giving the medicine compared to a dummy treatment.
Crohn's DiseaseHungary - Active not recruitingPHASE3
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer
This study looks at treating a specific type of advanced lung cancer. It compares two treatments, atezolizumab alone or combined with lurbinectedin, after initial chemotherapy. The aim is to see which approach works best to keep the cancer stable.
Small-Cell Lung CancerHungary - RecruitingPHASE3
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine
This study looks at a medicine called atogepant for children and teenagers aged 6 to 17 who get occasional migraines. It will check if the medicine is safe and if it helps reduce migraines, as there aren't many approved treatments for young people.
Episodic MigraineHungary - RecruitingPHASE2
A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis
This study is looking into a new medicine called Ianalumab for people in the UK with a specific type of scleroderma called diffuse cutaneous systemic sclerosis. It aims to see if the drug is safe and helps with symptoms, compared to a dummy treatment.
Diffuse Cutaneous Systemic SclerosisHungary - RecruitingPHASE3
A Study to See if Lepodisiran Can Reduce Plaque in Coronary Arteries of Adults With Elevated Lp(a) Who Have Had Heart Events or Are at High Risk
This study investigates a new medicine, lepodisiran, to reduce fatty deposits (plaque) in heart arteries. It's for adults aged 45-80 with high Lp(a), a type of cholesterol, who have heart problems or are at high risk. Researchers will use special scans to see if the medicine helps.
AtherosclerosisCardiovascular DiseasesLipoprotein(a)Hungary - Active not recruitingPHASE3
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
This study looks at a new drug, oregovomab, combined with standard chemotherapy for women with advanced ovarian cancer after surgery. Researchers want to see if this combination works better and is safe compared to chemotherapy alone.
Carcinoma, Ovarian EpithelialOvarian NeoplasmsOvarian CancerOvarian Serous AdenocarcinomaHungary - Not yet recruitingPHASE3
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
This study is looking at a new medication called KarXT combined with KarX-EC to help children and teenagers with autism who experience a lot of irritability. The aim is to see if this combination can make them feel less irritable.
Irritability Associated With Autism Spectrum DisorderHungary - Active not recruitingNA
Carotid Artery Implant for Preventing Stroke in Atrial Fibrillation Patients Taking Oral Anticoagulants
This study is looking at a new device called the Vine™ Embolic Protection System. It's like a tiny filter placed in the neck arteries to help prevent strokes in people with atrial fibrillation who are already taking blood thinners but are still at high risk.
Atrial FibrillationStrokeHungary - Recruiting
Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry
This study looks at how well a device called the Vercise DBS System works for people with Parkinson's disease. Researchers are gathering information from around the world to see how it helps with symptoms and improves daily life.
Parkinson's DiseaseHungary - Active not recruitingPHASE3
A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State
This study is looking at a new medicine called Dazodalibep for people with Sjögren's Syndrome. It aims to see how well it helps with symptoms and whether it's safe to use, especially for those with moderate to severe symptoms.
Sjögren's Syndrome (SS)Hungary - Active not recruitingPHASE3
Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Hormone Receptor-positive/Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Metastatic Breast Cancer Who Have Received Endocrine Therapy
This study looks at a new drug, Sacituzumab Govitecan, for advanced breast cancer. It compares it to standard treatments to see if it can slow cancer growth or spread, helping people live longer and healthier lives.
Locally Advanced or Unresectable Metastatic Breast CancerStage IV Breast CancerHungary - Active not recruitingPHASE3
A Study Comparing Risankizumab to Placebo in Participants With Active Psoriatic Arthritis Including Those Who Have a History of Inadequate Response or Intolerance to Biologic Therapy(Ies)
This study is testing a new medicine, risankizumab, for adults with active psoriatic arthritis, especially those who haven't responded well to other treatments. It aims to see how safe and effective it is in reducing symptoms.
Psoriatic Arthritis (PsA)Hungary - RecruitingNA
Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic Stroke Due to Primary Distal Medium Vessel Occlusions (DMVO)
This study looks at a new device called the iNstroke 4F catheter. It's for people who have had a specific type of stroke where small blood vessels in the brain are blocked. We want to see how safe and effective this device is at clearing these blockages.
Acute Ischemic StrokeHungary - Active not recruitingPHASE2
A Study to Evaluate the Long-Term Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (ACROBAT Advance)
This study looks at a new oral medicine called paltusotine for people with acromegaly. It checks how safe and effective it is over a long time for those who have already tried it in previous studies. The aim is to see if it continues to help manage the condition.
AcromegalyHungary - Active not recruitingPHASE4
CINC424A2X01B Rollover Protocol
This study is for patients already taking ruxolitinib, or ruxolitinib with panobinostat, in a previous trial, and who are still benefiting. It lets them continue their treatment and helps researchers learn more about the long-term safety of these medications.
Primary MyelofibrosisPolycythemia VeraGraft Versus Host DiseaseAcute Myeloid LeukemiaHungary - Active not recruitingPHASE3
A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study
This study allows some cancer patients who are already benefiting from certain treatments in another study to continue receiving that treatment. It’s for those who wouldn't be able to get the treatment otherwise, helping them keep accessing therapies that are working for them.
CancerHungary - Active not recruitingPHASE2
Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
This study is testing new treatments for advanced bladder cancer. It compares a new drug, zelenectide pevedotin, alone and with pembrolizumab, against standard chemotherapy. We want to see how well these treatments work and if they are safe for people with bladder cancer that has spread.
Metastatic Urothelial CancerHungary - RecruitingPHASE3
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
This study looks at how safe a new medicine called finerenone is for children and young people (aged 1-18) with long-term kidney disease, when taken with other common kidney medicines. It also checks if it helps reduce protein in their urine.
Chronic Kidney DiseaseProteinuriaChildrenHungary