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CCAAT enhancer binding protein alpha

The CEBPA gene provides instructions for making a protein called CCAAT enhancer-binding protein alpha. This protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity (expression) of certain genes. CCAAT enhancer-binding protein alpha is involved in the maturation (differentiation) of certain blood cells. It is also believed to act as a tumour suppressor, which means that it is involved in cellular mechanisms that help prevent the cells from growing and dividing too rapidly or in an uncontrolled way.

Normal function

The CEBPA gene provides instructions for making a protein called CCAAT enhancer-binding protein alpha. This protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity (expression) of certain genes. CCAAT enhancer-binding protein alpha is involved in the maturation (differentiation) of certain blood cells. It is also believed to act as a tumour suppressor, which means that it is involved in cellular mechanisms that help prevent the cells from growing and dividing too rapidly or in an uncontrolled way.

Conditions referring to this gene or chromosome

Other names

c/EBP alpha

C/EBP-alpha

CCAAT/enhancer binding protein (C/EBP), alpha

CCAAT/enhancer binding protein alpha

CCAAT/enhancer-binding protein alpha

CEBP

CEBPA_HUMAN

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Further reading and references

Article history

The information on this page is written and peer reviewed by qualified clinicians.
  • 18 Aug 2020 | Latest version
  • 1 Dec 2013 | Originally published

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