Can I take Anastrozole and Vitamin D together?

Why this happens

Anastrozole works by lowering oestrogen levels, which can lead to bone thinning (osteoporosis). Vitamin D helps the body absorb calcium, which strengthens bones and helps counteract this side effect. There are no known issues with how the body processes these two substances together.

What you should do

It is safe and often beneficial to take vitamin D while taking anastrozole. You should continue taking your supplements as directed by your doctor or pharmacist. It is a good idea to have your vitamin D levels checked periodically to ensure you are taking the correct dose for your bone health.

Important precautions

Pregnancy and breastfeeding

Anastrozole must not be taken if you are pregnant or breastfeeding, as it can cause serious harm to the unborn baby. It is only for use in women who have gone through the menopause.

Osteoporosis (bone thinning)

Anastrozole lowers oestrogen levels, which can significantly decrease bone mineral density and increase your risk of fractures. Your doctor should monitor your bone health before and during treatment.

Food and drink warnings

High-fat meals

Vitamin D is a fat-soluble vitamin. It is absorbed much more effectively when taken with a meal that contains some fat (such as yoghurt, eggs, or avocado). Taking it on an empty stomach may reduce its effectiveness.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.