When the aorta ruptures spontaneously, rather than as the result of trauma, it is usually in an aortic aneurysm. Rupture of an aortic aneurysm should not be confused with aortic dissection. Progressive aneurysm enlargement can lead to rupture and massive internal bleeding, which is a fatal event unless timely repair can be achieved.
The aorta is such a large blood vessel that, if it ruptures, death is very rapid, although the process might be slow enough to permit emergency surgery. However, time is of the essence. The ideal management is to repair the aneurysm before rupture occurs. Often there is no knowledge of the presence of an aneurysm and the first sign is rupture, rapid exsanguination and death.
Ruptured abdominal aortic aneurysms (AAAs) cause 6,000 deaths per year. Women are much less frequently affected.
The presence of an aneurysm is a risk for rupture[3, 4]. The larger the lesion, the more likely it is to bleed; aneurysms over 6 cm have a 25% annual risk of rupture. Smoking and hypertension are additional risks.
A dissecting or ruptured aneurysm usually presents with pain and collapse.
Thoracic aortic aneurysm (TAA)
- It will cause chest pain that may be indistinguishable from acute myocardial infarction in terms of nature and distribution.
- Haemoptysis can occur.
- If bleeding occurs into the mediastinum, it can cause cardiac tamponade and rapidly be fatal. The patient will probably never reach hospital alive and the diagnosis is made post-mortem.
Abdominal aortic aneurysm (AAA)
- Ruptured AAA presents with a classical triad of pain in the flank or back, hypotension and a pulsatile abdominal mass; however, only about half have the full triad.
- The patient will complain of the pain and may feel cold, sweaty and faint on standing.
- Other common symptoms include syncope and vomiting.
- A patient with a ruptured aneurysm at any level is likely to look pale and unwell and to be cold and sweaty.
- The pulse will be rapid, weak and thready. Hypotension is common.
- With a ruptured AAA there may well be a pulsatile mass in the vicinity of the bifurcation of the aorta. This is a few centimetres above the umbilicus and a little to the left.
- It may be tender and a bruit may be audible. Bleeding causes peritoneal irritation and it may appear as an acute abdomen.
- Occasionally the presentation can be atypical - eg, intestinal obstruction from haematoma or an apparent irreducible inguinal hernia.
- The differential diagnosis for a ruptured TAA is that of chest pain, especially myocardial infarction with cardiogenic shock but also massive pulmonary embolism.
- The differential diagnosis for ruptured AAA involves other causes of abdominal pain, including acute abdomen.
If an aneurysm is ruptured, investigations need to be swift and pertinent.
- FBC: NB: if there has not been time for haemodilution then haemoglobin will be normal. Anaemia is present in less than half of patients. Around 80% have a white cell count of 10 x 109/L or more.
- Group and rapid cross-match: whilst arranging surgery.
- Baseline biochemistry of U&Es: should be performed.
- CXR: for a TAA the CXR may well show an enlarged base of aorta.
- Plain abdominal X-ray: for an AAA this will show the lesion in about 75%, as it is often calcified.
- Portable ultrasound: this examination may be helpful but there is not time for detailed assessment. If there is strong suspicion of a ruptured aneurysm then immediate surgery may be the investigation of choice.
- Other investigations: CT angiography will confirm the diagnosis. MRI and angiography are an alternative but, practically, more time-consuming so probably only suitable for the stable patient.
- ECG: is important in patients presenting with chest pain.
This is a surgical emergency.
- Get large-bore intravenous access as soon as possible and preferably before hospital.
- Group and cross-match. Large supplies of blood and blood products, including platelets and fresh-frozen plasma, should be readily available.
- Arrange theatre immediately.
- The aim of surgery in an unstable patient is to secure surgical proximal aortic control without disturbing any tamponade effect provided by extra-aortic structures or haematoma.
- Resuscitation of hypovolaemic shock may require surgery to stem the bleeding rather than satisfactory resuscitation before induction of anaesthesia. Therefore an experienced anaesthetist is essential.
- Emergency endovascular aneurysm repair (EVAR) has been used successfully to treat ruptured AAA, proving that it is feasible in selected patients. A Cochrane review found insufficient data to evaluate the relative benefits and risks of endovascular treatment for ruptured AAA when compared with open repair. The National Institute for Health and Care Excellence still recommends open surgery for ruptured AAAs.
- Acute kidney injury.
- Multi-organ failure.
- Respiratory problems, including respiratory failure and pneumonia.
No more than one in three patients with a ruptured aortic aneurysm will reach hospital alive; 20% of those who do, fail to reach theatre. Delay in diagnosis is likely to result in death. Factors associated with an increased likelihood of poor outcome include increasing age of the patient, failure of initial resuscitation to increase the blood pressure and pre-operative cardiac arrest.
Further reading and references
Reite A, Soreide K, Kvaloy JT, et al; Long-Term Outcomes After Open Repair for Ruptured Abdominal Aortic Aneurysm. World J Surg. 2020 Jun44(6):2020-2027. doi: 10.1007/s00268-020-05457-7.
Karthaus EG, Lijftogt N, Vahl A, et al; Patients with a Ruptured Abdominal Aortic Aneurysm are Better Informed in Hospitals with an 'EVAR-preferred' Strategy: An Instrumental Variable Analysis of the DSAA. Ann Vasc Surg. 2020 Jun 15. pii: S0890-5096(20)30516-1. doi: 10.1016/j.avsg.2020.06.015.
Badger SA, Harkin DW, Blair PH, et al; Endovascular repair or open repair for ruptured abdominal aortic aneurysm: a Cochrane systematic review. BMJ Open. 2016 Feb 126(2):e008391. doi: 10.1136/bmjopen-2015-008391.
Aortic Aneurysms; British Society of Interventional Radiology, 2018
Baliga RR, Nienaber CA, Bossone E, et al; The role of imaging in aortic dissection and related syndromes. JACC Cardiovasc Imaging. 2014 Apr7(4):406-24. doi: 10.1016/j.jcmg.2013.10.015.
Thrumurthy SG, Karthikesalingam A, Patterson BO, et al; The diagnosis and management of aortic dissection. BMJ. 2011 Jan 11344:d8290. doi: 10.1136/bmj.d8290.
Franz RW, Nardy VJ, Burkdoll D; Endovascular repair of a large ruptured abdominal aortic aneurysm using monitored anesthesia care and local anesthesia. Int J Angiol. 2014 Jun23(2):121-4. doi: 10.1055/s-0034-1376884.
Badger S, Forster R, Blair PH, et al; Endovascular treatment for ruptured abdominal aortic aneurysm. Cochrane Database Syst Rev. 2017 May 265:CD005261. doi: 10.1002/14651858.CD005261.pub4.
Abdominal aortic aneurysm: diagnosis and management; NICE Guidance (March 2020)