Bisoprolol - a beta-blocker

About bisoprolol

What is bisoprolol used for?

Bisoprolol is a type of beta-blocker used to treat high blood pressure, chest pain (angina), and heart failure.

Bisoprolol works on the heart and blood vessels. It does this by blocking tiny areas (called beta-adrenergic receptors) where messages sent by some nerves are received by your heart and blood vessels. As a result, your heart beats more slowly and with less force. The pressure of blood within your blood vessels is reduced and it is easier for your heart to pump blood around your body.

These actions are of benefit if you have high blood pressure (hypertension), or if you have heart failure which is a condition where your heart is not working as well as it should. Because your heart is using less energy, it also helps to reduce chest pain if you have angina.

Side effects of bisoprolol

The most common side effects of bisoprolol are:

• Feeling dizzy or lightheaded.

• Feeling sleepy or tired.

• Feeling sick (nausea).

• Being sick (vomiting).

• Diarrhoea.

• Constipation.

• Headache.

• Cold fingers and toes.

• Disturbed sleep.

• Slow heartbeat.

You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

How to manage bisoprolol side effects

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

Who should not take bisoprolol?

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking bisoprolol it is important that your doctor knows:

• If you are pregnant or breastfeeding.

• If you have asthma or any other breathing disorder.

• If you have any problems with the way your liver works, or if you have any problems with the way your kidneys work.

• If you have low blood pressure or poor circulation.

• If you have diabetes.

• If you have a skin problem called psoriasis.

• If you have a condition causing muscle weakness, called myasthenia gravis.

• If you have been told you have a slow heartbeat or heart block (a slow and irregular heartbeat).

• If you have been told you have chest pain caused by spasms of your heart's blood vessels, called Prinzmetal's angina.

• If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

• If you have ever had an allergic reaction to a medicine, or if you have ever had any other serious allergic reaction.

How to take bisoprolol

• Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about bisoprolol and will provide you with a full list of side effects which you may experience from taking it.

• Take bisoprolol exactly as your doctor tells you to. The usual dose is one tablet each day, although the strength of your tablet will depend upon the reason why you are taking it.

• If you are taking it for heart failure, you will be started on a low-strength tablet (1.25 mg) and then you will be prescribed a different strength of tablet each week for the first few weeks. This is so your doctor can increase your dose gradually.

  • Your dose and the strength of the tablets will be on the label of the pack. There are several strengths of tablet available: 1.25 mg, 2.5 mg, 3.75 mg, 5 mg, 7.5 mg and 10 mg.

  • Each time you collect a fresh supply of tablets it is a good idea to check to make sure you receive the strength you are expecting. If you have any questions, please ask your pharmacist to advise you.

• You can take the tablets either with or without food, but try to take your doses at the same time of day each day as this will help you to remember to take bisoprolol regularly. The tablets are best swallowed in the morning with a drink of water.

• If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, leave out the forgotten dose from the previous day and take the dose that is due as normal. Do not take two doses at the same time to make up for a missed dose.

Getting the most from your treatment

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

• If you are due to have an operation or dental treatment, it is important to tell the person carrying out the treatment that you are taking a beta-blocker. This is particularly important if you are likely to be given an anaesthetic.

• If you drink alcohol, ask your doctor for advice about taking bisoprolol and alcohol. Alcohol will add to the blood pressure-lowering effect of bisoprolol which will make you feel dizzy and so may not be recommended for you.

• If you buy any medicines, check with a pharmacist that they are suitable for you to take with bisoprolol. Some medicines may not be (including some anti-inflammatory painkillers, and cold or flu remedies).

• Your doctor may give you dietary and lifestyle advice about eating a healthy diet, not smoking, and taking regular exercise. If so, it is important that you follow the advice you are given.

• If you have diabetes, bisoprolol can block the symptoms of low blood sugar. Your doctor will advise you about this.

• Treatment with bisoprolol is usually long-term. Continue to take the tablets unless your doctor tells you to stop. Stopping treatment suddenly can cause problems in some people, so your doctor may want you to reduce your dose gradually if this becomes necessary.

How to store bisoprolol

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

Frequently asked questions

Can you take apixaban and bisoprolol together?

Yes, apixaban and bisoprolol are sometimes prescribed together, especially for people with heart conditions such as atrial fibrillation. Apixaban helps prevent blood clots, while bisoprolol lowers blood pressure and reduces strain on the heart.

Why am I so tired on bisoprolol?

Feeling tired is a common side effect of bisoprolol. The medicine slows your heart rate and reduces how hard your heart has to work, which can sometimes leave you feeling fatigued, especially when you first start taking it. For most people this improves over time.

What can you not take with bisoprolol?

Bisoprolol can interact with other heart medicines, some antidepressants, asthma inhalers, and decongestants. Always check with your doctor or pharmacist before taking bisoprolol.

Is bisoprolol a blood thinner?

Bisoprolol is not a blood thinner – it’s a beta-blocker used to slow heart rate and lower blood pressure.