Felodipine is taken once a day.
You can take the tablet before or after meals.
When you first start taking felodipine you may get a headache or feel flushed. These symptoms usually go after a few days.
Do not drink grapefruit juice while you are taking felodipine.
|Type of medicine||Calcium-channel blocker|
|Used for||High blood pressure; angina|
|Also called||Cardioplen® XL; Felotens® XL; Folpik® XL; Neofel® XL; Plendil®; Vascalpha®|
Combination brand: Triapin® (felodipine with ramipril)
|Available as||Modified-release tablets|
Felodipine works by causing some of your blood vessels to relax and widen. This lowers your blood pressure. It also reduces the force and the rate of your heartbeat, and this helps to prevent angina chest pain. It does these things by blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of your arteries and in your heart. Calcium is needed for muscles to contract, so reducing the amount of calcium causes the muscle cells to relax.
Felodipine is manufactured as a modified-release tablet. This means that the tablets release felodipine slowly and evenly throughout the course of the day. Felodipine is also available as a combination tablet with a medicine called ramipril, which also reduces high blood pressure. Combination tablets help to reduce the total number of tablets you need to take each day.
Before taking felodipine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking felodipine it is important that your doctor knows:
- If you have any heart problems (other than angina or high blood pressure).
- If you are pregnant or breastfeeding.
- If you have problems with the way your liver works.
- If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
- If you have ever had an allergic reaction to a medicine.
How to take felodipine
- Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. It will give you more information about felodipine and will provide you with a full list of the side-effects which you may experience from taking the tablets.
- Felodipine is taken once a day. There are three strengths of felodipine tablets available - 2.5 mg, 5 mg and 10 mg. It is common to be prescribed the 5 mg strength tablets at first. Your doctor will tell you which is right for you.
- Take your tablet in the morning. Swallow it whole with a drink of water. Do not break, crush or chew the tablet, as this will affect the way the medicine is released into your bloodstream. You can take felodipine either before or after you have breakfast.
- If you forget to take a dose at your usual time, take it as soon as you remember. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Getting the most from your treatment
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
- Your doctor will discuss with you the possibility of unwanted side-effects. When you first start taking felodipine you may experience headaches, feeling flushed, and some dizziness. These effects usually only last for a few days, but if they continue or become troublesome, you should let your doctor know.
- If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on this medicine, as it may increase the chance that you experience side-effects, such as feeling dizzy or light-headed.
- Treatment with felodipine is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are told otherwise by your doctor. If it is necessary for you to stop, your doctor may want you to reduce your dose over a few days, as there is some evidence to suggest that stopping taking felodipine suddenly can cause some symptoms to return.
- If you buy any medicines, always check with a pharmacist that they are suitable to take with your other medicines. Some anti-inflammatory painkillers may reduce the effectiveness of felodipine.
- If you need to have an operation or any medical treatment, always tell the person carrying out the treatment which medicines you are taking. Felodipine and some anaesthetics can interact, meaning that unwanted effects are more likely.
- It is not advisable for you to drink grapefruit juice while you are taking felodipine. This is because a chemical in grapefruit juice can increase the amount of felodipine in your bloodstream and this can increase the risk of side-effects.
Can felodipine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with felodipine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
|Common felodipine side-effects (these affect fewer than 1 in 10 people)||What can I do if I experience this?|
|Headache, feeling flushed||These may occur when you first start treatment, but usually go away after a few days. If the headache continues, ask your pharmacist to recommend a suitable painkiller, or discuss the problem with your doctor|
|Swollen ankles||Take plenty of rest and raise your legs on to a low stool when you are sitting|
Important: a few people taking felodipine have experienced worsening of chest pain at the start of treatment - if this happens to you, you must let your doctor know straightaway.
If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.
How to store felodipine
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Further reading and references
Manufacturer's PIL, Plendil® 2.5 mg, 5 mg and 10 mg tablets; AstraZeneca UK Limited, The electronic Medicines Compendium. Dated June 2019.
British National Formulary, 79th Edition (Mar 2020); British Medical Association and Royal Pharmaceutical Society of Great Britain, London.