PatientPlus articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use, so you may find the language more technical than the condition leaflets.
See also separate Screening for Dementia article.
This informant questionnaire can be very useful in the screening and evaluation of dementia. When combined with cognitive tests such as the Mini Mental State Examination (MMSE), an useful overview is obtained and hence sensitivity and specificity as a screening test can be improved Validity within primary and secondary care settings has been tested. A shortened 16-question form of the IQCODE has also been validated and is shown here.
Each question is scored from 1 (much improved) to 5 (much worse). For the Short IQCODE, a cut-off point (average score) of 3.31/3.38 achieves a balance of sensitivity and specificity.
Short Form of the Informant Questionnaire on Cognitive Decline in the Elderly (Short IQCODE) by A. F. Jorm, Centre for Mental Health Research, The Australian National University, Canberra, Australia.
Note: as used in published studies, the IQCODE was preceded by questions to the informant on the subject's sociodemographic characteristics and physical health.
Further reading & references
- Jorm AF, Scott R, Cullen JS, et al; Performance of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as a screening test for dementia. Psychol Med. 1991 Aug;21(3):785-90.
- Cherbuin N, Anstey KJ, Lipnicki DM; Screening for dementia: a review of self- and informant-assessment instruments. Int Psychogeriatr. 2008 Jun;20(3):431-58. Epub 2008 Feb 21.
- Mackinnon A, Mulligan R; Combining cognitive testing and informant report to increase accuracy in screening for dementia. Am J Psychiatry 1998 Nov; 155:1529–35
- Harrison JK, Fearon P, Noel-Storr AH, et al; Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting. Cochrane Database Syst Rev. 2014 Jul 3;7:CD010771. doi: 10.1002/14651858.CD010771.pub2.
- Harrison JK, Fearon P, Noel-Storr AH, et al; Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting. Cochrane Database Syst Rev. 2015 Mar 10;3:CD010772. doi: 10.1002/14651858.CD010772.pub2.
- Jorm AF; A short form of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): development and cross-validation. Psychol Med. 1994 Feb;24(1):145-53.
- Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE); Australian National University
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Dr Huw Thomas
Dr Hayley Willacy
Dr Colin Tidy