Obstetric ultrasound was first introduced in the late 1950s. It is now widely used and has become a useful tool in monitoring and diagnosis. Ultrasound scans use sound waves which are safe for you and your baby.
The first ultrasound scan is usually performed before 15 weeks. The purpose is to:
- Diagnose pregnancy.
- Accurately determine gestational age - this is essential for intervention of post-maturity, and for accurate serum screening for Down's syndrome.
- Determine viability - to confirm the presence of a heartbeat and exclude ectopic pregnancy and hydatidiform mole.
- Determine fetal number and, in multiple pregnancies, the chorionicity/amnionicity.
- Detect gross fetal abnormalities.
- Measurement of crown-rump length accurately measures gestational age if performed before 13 weeks. After 13 weeks, the fetus becomes increasingly flexed so results are inaccurate. Alternatives that can be used after this include bi-parietal diameter, and/or head circumference, or femur length.
- it is usually performed abdominally, although occasionally a vaginal scan is necessary.
- Nuchal translucency scans for risk of Down's syndrome are best performed between 10-14 weeks.
Screening for structural abnormalities - anomaly scan
This scan is offered to pregnant women ideally between 18-20 weeks of gestation. This scan can provide dating information and diagnosis of multiple pregnancy, in units where no booking scan is performed.
The main purpose is:
- To reassure the mother that her baby appears to have no gross structural abnormalities:
- 50% of significant abnormalities will be detected by the 20-week screening scan.
- To provide the parents with options - eg, termination, preparation, and appropriate care throughout the rest of the pregnancy and delivery.
- To determine placental morphology and localisation:
- Where the placenta extends across the internal cervical os, another scan at 36 weeks should be offered.
- To confirm that fetal growth is appropriate.
- Assess growth by the measurement methods below:
- Bi-parietal diameter (most accurate for dating up to 20 weeks)
- Head circumference
- Femur length
- Abdominal circumference
- Look at the head shape and internal structures:
- Cavum septum pellucidum
- Ventricular size at atrium (<10 mm)
- Minimum standards:
- Spine: longitudinal and transverse
- Abdominal shape and content at the level of the stomach
- Abdominal shape and content at the level of the kidneys and umbilicus
- Renal pelvis (<5 mm AP measurement)
- Longitudinal axis - abdominal-thoracic appearance (diaphragm/bladder)
- Thorax at level of four-chamber cardiac view
- Aortic arch
- Arms - three bones and hand (not counting the fingers)
- Legs - three bones and orientation of feet (not counting the toes)
- Optimal standards:
- Cardiac outflow tracts
- Face, nose and lips; 15% of women may have to return for further checks
Aneuploidy scans are not routinely performed, as many normal pregnancies may have some of these features - ie there is a high false-positive rate. Pregnancies affected by aneuploidy (abnormal chromosome number) will have sonographic markers. However, 50-80% of affected cases will already be identified by triple test, maternal age and nuchal translucency measurements.
Indications for a 'marker' scan include:
- Family history of abnormalities, such as a neural tube defect (NTD)
- Multiple pregnancies
- Maternal diabetes or epilepsy
- Recurrent miscarriage
- Alpha-fetoprotein (AFP) abnormal/maternal age >35 years
|Ultrasound checklist for screening for aneuploidy|
|Common sonographic 'markers' for aneuploidy||Other risk factors|
|Choroid plexus cyst||Maternal age|
|Ventriculomegaly (>10 mm at the atrium)||Serum screening results|
|Echogenic bowel (equivalent to bone density)||Nuchal translucency (10- to 14-week scan)|
|Nuchal pad (>5 mm at 20 weeks)|
|Echogenic foci in heart|
|Dilated renal pelvis (>5 mm AP)|
These are set by the Royal College of Obstetricians and Gynaecologists to assure the quality of service provision. They include providing clear, written advice that includes detection rates for defined, common conditions. A trained counsellor in the area of diagnosis and screening should be available, as should a quiet room for breaking bad news about the baby. It should be possible to discuss the findings with an obstetrician within 24 hours or soon after detection of the anomaly.
Potential detection rates based on Royal College of Obstetrics and Gynaecology screening strategy
Using the standard 20-week scan checklist:
- Anencephaly - 100%
- Spina bifida - 92%
- Major cardiac anomalies (hypoplastic ventricle) - 61%
- Diaphragmatic hernia - 62%
- Gastroschisis - 100%
- Exomphalos - 92%
- Major renal tract problems (renal agenesis) - 85%
Fetal presentation and cervical length
- Suspected fetal malpresentation (eg, breech) should be confirmed by an ultrasound examination after 36 weeks.
- Cervical length measured by transvaginal ultrasonography in asymptomatic high-risk women predicts spontaneous preterm birth at less than 35 weeks of gestation.
Biophysical profile screening
This is a type of fetal assessment using specific criteria to reach a well-being score for high-risk pregnancies. It is based on the Apgar scoring system used to assess the condition of the newborn.
It was introduced in the 1980s and, despite minor refinements of the original test, the assessments still include five main features:
- Monitoring of fetal movements
- Fetal tone
- Fetal breathing
- Assessment of amniotic fluid volume
- Assessment of fetal heart rate by electronic monitoring
Biophysical profile fetal assessment is based on the association between low biophysical scores and poor pregnancy outcome.Hence, the procedure aims to detect acute and chronic fetal compromise with changes in fetal heart patterns, decreased body and breathing movements, reduced amniotic fluid, oliguria, and redistribution of regional blood flow leading to a reduction in fetal renal blood flow.
The usual ultrasound scans in pregnancy use sound waves which are safe for you and your baby but cannot show blood flow. Doppler ultrasound uses high-intensity sound waves to detect the blood circulation in the baby, uterus and placenta.
- The application has extended from the umbilical cord to fetal vessels (aorta, cerebral and renal arteries) as well as maternal vessels supplying the placental intervillous space.
- It is used for high-risk pregnancies where there is concern about baby's well-being - eg, intrauterine growth restriction, hypertensive disorders of pregnancy - and to distinguish between the normal small fetus and the 'sick' small fetus.
- Despite its advances, Doppler ultrasound is not of use in routine antenatal screening because several studies have shown it is an unnecessary intervention and may cause possible adverse effects. Its current role in optimising management, particularly timing of delivery, remains unclear.
Further reading and references
Woo JSK; Obstetric Ultarsound, a Comprehensive Guide
Ultrasound screening; Royal College of Obstetricans and Gynaecologists, 2000
Antenatal care for uncomplicated pregnancies; NICE Clinical Guideline (March 2008, updated 2017)
Crane JM, Hutchens D; Transvaginal sonographic measurement of cervical length to predict preterm birth in asymptomatic women at increased risk: a systematic review. Ultrasound Obstet Gynecol. 2008 May31(5):579-87. doi: 10.1002/uog.5323.
Lalor JG, Fawole B, Alfirevic Z, et al; Biophysical profile for fetal assessment in high risk pregnancies. Cochrane Database Syst Rev. 2008 Jan 23(1):CD000038. doi: 10.1002/14651858.CD000038.pub2.
Westergaard HB, Langhoff-Roos J, Lingman G, et al; A critical appraisal of the use of umbilical artery Doppler ultrasound in high-risk pregnancies: use of meta-analyses in evidence-based obstetrics. Ultrasound Obstet Gynecol. 2001 Jun17(6):466-76.
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