Professional Reference articles are written by UK doctors and are based on research evidence, UK and European Guidelines. They are designed for health professionals to use, so you may find the language more technical than the condition leaflets.
A bursa is a small sac of fibrous tissue with a thin synovial lining that is filled with fluid. Numerous bursae are found in the body, around joints and in places where ligaments and tendons pass over bones. They can also form in other places as a response to unusual pressure or friction. Generally, bursae help to reduce friction and allow maximal range of motion around joints. Bursitis is inflammation within a bursa. The inflammation leads to an increase in synovial fluid production and causes the bursa to swell.
There are four bursae located around the knee joint. They are all susceptible to bursitis but the prepatellar bursa is most commonly affected. Less frequently, the infrapatellar and deep patellar bursae can become inflamed.
The prepatellar bursa is located superficially on the anterior aspect of the knee between the skin and the patella. The bursa does not communicate with the knee joint and the knee joint itself is normal in prepatellar bursitis.
Prepatellar bursitis may occur due to:
- Acute trauma: fall/direct blow on to the knee.
- Recurrent minor injury: occurs after long periods of time spent kneeling forwards and putting pressure on the patella. Historically, this was typical of housemaids who spent long periods of time on their knees scrubbing floors; hence, the term 'housemaid's knee'. It is now more commonly seen in tradesmen - eg, carpet fitters, concrete finishers, roofers.
- Infection: pyogenic prepatellar bursitis is common in children. It may be mistaken for septic arthritis of the knee. Staphylococcus aureus is the usual causal agent. There is usually a history of a break in the skin prior to its onset.
- A co-existing inflammatory disease: for example, synovitis related to rheumatoid arthritis.
- A crystal-depositing condition: prepatellar bursitis is more common in people with gout or pseudogout.
- All age groups can be affected.
- It is more likely to have a septic aetiology in children and the immunocompromised.
See also separate Knee Assessment article.
- Knee pain, swelling and redness.
- Difficulty kneeling and walking.
- Tenderness and swelling superficial to the patella.
- Erythema and localised warmth of the skin over the patella.
- Reduced knee movement.
- Fever, tachycardia or signs of systemic upset may indicate septic bursitis.
Key points to elicit in the history
- Occupation - establish if this involves excessive kneeling.
- Ask whether there is a history of a fall or acute knee injury.
- Ask whether there is history of any repetitive motion involving the knee.
- Establish whether there has been recent steroid treatment.
- Determine whether the patient is immunocompromised.
- Ask whether there Is a history of crystal arthropathy or inflammatory disease.
- Patellofemoral pain syndrome.
- Septic arthritis of the knee: clinical judgement should be used to distinguish between prepatellar bursitis and septic arthritis. The swelling in bursitis is usually distinguishable as being prepatellar but, if very large, the whole knee can appear swollen. If uncertain, refer for a specialist opinion.
- Knee joint effusion secondary to trauma.
- Infrapatellar bursitis: bursitis may also affect the infrapatellar bursa. This has the synonyms 'parson's knee', or 'vicar's knee'. Management follows the same principles as prepatellar bursitis.
Aspiration of the prepatellar bursa
it is important to differentiate septic and non-septic bursitis. If infection is suspected, fluid should be aspirated under aseptic conditions by an experienced physician and sent for culture. Aspirate should be examined for:
- White cell count - this may be 5000/μL or greater.
- Protein - may be raised.
- Lactate - may be raised.
- Glucose - may be decreased.
- Culture - the presence of Gram-negative bacteria may indicate septic bursitis.
- Monosodium urate crystals - indicate gout.
- Calcium pyrophosphate crystals - indicate pseudogout.
- Cholesterol crystals - may be present in rheumatoid arthritis.
This is not usually required for uncomplicated cases. However, plain X-ray may be required if fracture or dislocation is a clinical possibility. MRI or CT may be required in cases where there is a failure to respond to treatment for septic prepatellar bursitis. Ultrasound may also be useful for diagnosis.
The management of prepatellar bursitis depends on its aetiology. When considering management, separate into septic and non-septic bursitis. According to one study, patients with septic bursitis usually presented earlier and had more pain, erythema, warmth and tenderness, and some had mild fever (37.5°C maximum recorded). Clinical features alone could not identify all the septic cases. Have a low threshold for performing, or referring for, aspiration.
- Patient education about the condition and its aetiology.
- A thick foam cushion, or knee pads, to kneel on can help prevent recurrence. Occupational therapy referral may be helpful.
- Physiotherapy referral may be helpful if there is reduced range of movement in the knee joint. A stick or cane may be needed to aid walking.
- Aspiration of the prepatellar bursa and injection of a corticosteroid: infection must be excluded prior to this. Complications should be discussed with the patient, including infection, subcutaneous atrophy, bleeding and patellar tendon rupture. Hydrocortisone may be used.
- Non-steroidal anti-inflammatory drugs (NSAIDs) - eg, ibuprofen: these can be used for mild-to-moderate pain and to reduce inflammation
This may be needed if prepatellar bursitis is chronic or recurrent:
- Arthroscopic bursectomy: this can be performed under local anaesthetic on an outpatient basis. The cosmetic effect is better than open bursectomy.
- Open bursectomy: the traditional open surgical approach of excising the bursa.
Prepatellar septic bursitis is usually successfully managed non-operatively with rest, compression, immobilisation, aspiration and antibiotics. Surgical bursectomy may rarely be required for recalcitrant cases.
- Aspiration: this should be performed to confirm septic bursitis as detailed in 'Investigations', above. Guidance on diagnosis can be obtained rapidly from the aspirated fluid white cell count whilst waiting for culture results. Take care here because if the knee joint is opened, septic arthritis will ensue.
- Antibiotic therapy: if septic bursitis is suspected and whilst waiting for confirmatory culture results, start antibiotics. Intravenous antibiotics should be used if the patient is systemically unwell. Cephalosporins or penicillinase-resistant penicillins (eg, augmentin), or a combination of phenoxymethylpenicillin and flucloxacillin may be prescribed but get advice from your local microbiologist.
- Incision and drainage: if symptoms of septic bursitis have not improved significantly within 36-48 hours of antibiotic treatment, incision and drainage are usually performed.
Prepatellar bursitis can lead to pain and reduced function of the knee joint. This may be worse if septic bursitis is not recognised promptly. Generally the prognosis is very good with appropriate treatment.
- Education to avoid prolonged and repetitive kneeling.
- Use of knee pads in certain occupations.
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Further reading & references
- Bursae and Bursitis of the Knee; Wheeless' Textbook of Orthopaedics
- Pre-patellar bursitis; NICE CKS, July 2015 (UK access only)
- Iagnocco A, Vavala C, Scirocco C, et al; Unilateral painful, swollen and erythematosus knee. Case report. Med Ultrason. 2012 Sep 14(3):251-3.
- Aaron DL, Patel A, Kayiaros S, et al; Four common types of bursitis: diagnosis and management. J Am Acad Orthop Surg. 2011 Jun 19(6):359-67.
- Huang YC, Yeh WL; Endoscopic treatment of prepatellar bursitis. Int Orthop. 2011 Mar 35(3):355-8. doi: 10.1007/s00264-010-1033-5. Epub 2010 Jun 4.
- Gendernalik JD, Sechriest VF 2nd; Prepatellar septic bursitis: a case report of skin necrosis associated with open bursectomy. Mil Med. 2009 Jun 174(6):666-9.
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