Carpal tunnel syndrome is a set of symptoms thought to be caused by squashing (compression) of the median nerve in the carpal tunnel.
Carpal tunnel syndrome is a collection of symptoms - with pain as the main problem - that result from squashing of the median nerve as it runs through the carpal tunnel.
What is the carpal tunnel?
There are eight small bones called carpal bones in the wrist. A ligament (also called retinaculum) lies across the front of the wrist. Between this ligament and the carpal bones is a space called the carpal tunnel. The tendons that attach the forearm muscles to the fingers pass through the carpal tunnel. A main nerve (median nerve) to the hand also goes through this tunnel before dividing into smaller branches in the palm.
The median nerve gives feeling to the thumb, index and middle fingers, and half of the ring finger. It also controls the movement of the small muscles at the base of the thumb.
What is carpal tunnel syndrome?
This syndrome is a set of symptoms thought to be caused by squashing (compression) of the median nerve in the carpal tunnel. In terms of age, carpal tunnel syndrome is more common in:
- People in their late 50s, particularly women.
- People in their late 70s, when men and women are equally affected.
Carpal tunnel syndrome is more common in people who are obese and it often runs in families. It is more common in women who are pregnant.
What causes carpal tunnel syndrome?
In most cases it is not clear why it occurs. An increase in pressure going through the carpal tunnel is thought to squash (compress) and restrict the blood supply to the median nerve. As a result, the function of the median nerve is affected causing the symptoms.
- Your genes may play a part. There seems to be some inherited (genetic) factor. About 1 in 4 people with carpal tunnel syndrome have a close family member (father, mother, brother, sister) who also has or had the condition.
- Bone or arthritic conditions of the wrist, such as rheumatoid arthritis or wrist fractures, may lead to carpal tunnel syndrome.
- Various other conditions are associated with carpal tunnel syndrome. For example: pregnancy, obesity, an underactive thyroid gland, diabetes, the menopause, other rare diseases, and a side-effect of some medicines. Some of these conditions cause water retention (oedema) which may affect the wrist and cause carpal tunnel syndrome.
- Rare causes include cysts, growths, and swellings coming from the tendons or blood vessels passing through the carpal tunnel.
What are the symptoms of carpal tunnel syndrome?
- Pins and needles. This is tingling or burning in part or all of the shaded area (see diagram above). This is typically the first symptom to develop. The index and middle fingers are usually first to be affected.
- Pain in the same fingers may then develop. The pain may travel up the forearm and even to the shoulder.
- Numbness of the same finger(s), or in part of the palm, may develop if the condition becomes worse.
- Dryness of the skin may develop in the same fingers.
- Weakness of some muscles in the fingers and/or thumb occurs in severe cases. This may cause poor grip and eventually lead to muscle wasting at the base of the thumb.
Symptoms tend to come and go at first, often after you use the hand. Typically, symptoms are worse at night and may wake you up.
The symptoms may be eased for a while by raising the hand up or hanging it down. Flicking the wrist may also give relief. Symptoms persist all the time if the condition becomes severe.
Do I need any tests?
Often the symptoms are so typical that no tests are needed to confirm the diagnosis.
If the diagnosis is not clear then a test to measure the speed of the nerve impulse through the carpal tunnel (nerve conduction test) may be advised. A slow speed of impulse down the median nerve will usually confirm the diagnosis. Some people may also be referred for an ultrasound scan or a magnetic resonance imaging (MRI) scan to look at their wrist in more detail.
What are the treatment options?
In up to 1 in 4 cases the symptoms go without treatment within a year or so. Symptoms are most likely to go in people less than 30 years of age.
Try not to over-use your wrist by excessive squeezing, gripping, wringing, etc. If you are overweight, losing some weight may help. Painkillers may be prescribed to ease the pain. If the condition is part of a more general medical condition (such as arthritis) then treatment of that condition may help.
Not treating may be an option
In about 2 in 3 cases that develop during pregnancy, the symptoms go after the baby is born. So, not treating is an option, particularly if symptoms are mild. The situation can be reviewed if symptoms become worse.
A wrist splint
A removable wrist splint (brace) is often advised as a first active treatment. The aim of the splint is to keep the wrist at a neutral angle without applying any force over the carpal tunnel so as to rest the nerve. This may cure the problem if used for a few weeks. However, it is common to wear a splint just at night, which is often sufficient to ease symptoms.
A steroid injection
An injection of steroid into, or near to, the carpal tunnel is an option. One research trial found that a single steroid injection eased symptoms in about 3 in 4 cases. In this trial the symptoms returned in some people over the following year. Other studies report variable success rates with steroid injections.
Surgery is recommended for severe cases but the jury is still out as to whether it is better than injections for moderate symptoms. A large trial is being conducted to answer this question.
A small operation can cut the ligament over the front of the wrist and ease the pressure in the carpal tunnel to give your nerve more space. This usually cures the problem. It is usually done under local anaesthetic. There are two main types of surgery - open and keyhole. Your surgeon will discuss which technique is appropriate for you.
You will not be able to use your hand for work for a few weeks after the operation. A small scar on the front of the wrist will remain. There is a small risk of complications from surgery. For example, following surgery there is a very small risk of infection and damage to the nerve or blood vessels. Sometimes, the nerve can get caught up in the scar and become stretched when the wrist is moved: this is known as tethering.
Over the years, a wide range of other treatments has been tried. For example, controlled cold therapy, ice therapy, laser therapy and exercises. None of these treatments has good research evidence to support its use and so they are not commonly advised. However, they can work for some people. There is some evidence that acupuncture may relieve symptoms in some people.
Steroid tablets may ease symptoms in some cases. However, there is a risk of serious side-effects from taking a long course of steroid tablets. Also, a local injection of a steroid (described above) probably works better. Therefore, steroid tablets are not usually advised.
Which is the best treatment for me?
A non-surgical option may be advised if your symptoms are mild - for example, if your symptoms come and go and mainly consist of tingling, pins and needles or mild discomfort. A wrist splint (brace) may work but a steroid injection is probably the most effective non-surgical treatment.
If you try a non-surgical treatment and it does not work, do return to your doctor. In particular, see your doctor if you have constant numbness in any part of your hand, or if you have any weakness of the muscles next to the thumb. These symptoms mean that the nerve is not working well and is at risk of permanent damage.
Surgery gives the best chance of long-term cure. It is quite a common operation. It is done if symptoms continue (persist) despite other treatments, or if symptoms are severe and the nerve is in danger of permanent damage.
Treatment for severe symptoms
If you have severe symptoms - in particular wasting of the muscles at the base of the thumb - then you will probably need surgery. This is to relieve pressure on (decompress) the trapped nerve quickly, which aims to prevent any permanent long-term nerve damage.
Carpal tunnel syndrome during pregnancy
Symptoms commonly go after the baby is born. Therefore, a non-surgical treatment, such as a splint, is usually advised at first. Surgery is an option if symptoms persist.
Carpal Tunnel Syndrome Management Options
Each treatment option for Carpal Tunnel Syndrome has various benefits, risks and consequences. In collaboration with health.org.uk, we've put together a summary decision aid that encourages patients and doctors to discuss and assess what's available.
Further reading and references
Vasiliadis HS, Georgoulas P, Shrier I, et al; Endoscopic release for carpal tunnel syndrome. Cochrane Database Syst Rev. 2014 Jan 311:CD008265. doi: 10.1002/14651858.CD008265.pub2.
Ghasemi-Rad M, Nosair E, Vegh A, et al; A handy review of carpal tunnel syndrome: From anatomy to diagnosis and treatment. World J Radiol. 2014 Jun 286(6):284-300. doi: 10.4329/wjr.v6.i6.284.
Carpal tunnel syndrome; NICE CKS, September 2016 (UK access only)
Mason W, Ryan D, Khan A, et al; Injection versus Decompression for Carpal Tunnel Syndrome-Pilot trial (INDICATE-P)-protocol for a randomised feasibility study. Pilot Feasibility Stud. 2017 Apr 243:20. doi: 10.1186/s40814-017-0134-y. eCollection 2017.
Lyon C, Syfert J, Nashelsky J; Clinical Inquiry: Do corticosteroid injections improve carpal tunnel syndrome symptoms? J Fam Pract. 2016 Feb65(2):125-8.
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