Roundworms (also called nematodes) are worms with a long round body. They vary in length from several millimetres to up to two metres. Roundworms are common in warm tropical countries. Children are more often affected than adults. Treatment is usually very effective but wiping out (eradication of) roundworm infections has proved to be very difficult.
Can humans get roundworms?
About 60 types (species) of roundworm can live in (are parasites of) humans. They usually live in the human gut. However, some species can travel from the gut to live in different parts of the body.
Roundworm eggs and tiny young worms (larvae) live in the soil. They most commonly get into the body when a person gets them on his or her hands and then transfers them to the mouth. Some can also get into the body through the skin.
Examples of roundworms
- Ascaris lumbricoides (also called human roundworm), which is the most common roundworm infection, and affects as many as one billion people worldwide.
- Hookworm infections.
- Guinea worm disease (dracunculiasis).
- Filariasis, which is caused by thread-like filarial nematodes (roundworms) in the family Filarioidea (also known as filariae). There are eight known filarial nematodes which use humans as the host. These are divided into three groups:
- Lymphatic filariasis - caused by the worms Wuchereria bancrofti, Brugia malayi, and Brugia timori.
- Cutaneous filariasis - caused by Loa loa (the African eye worm), Mansonella streptocerca and Onchocerca volvulus.
- Body cavity filariasis - caused by the worms Mansonella perstans and Mansonella ozzardi.
- Threadworm (pinworm) - see separate leaflet called Threadworms for more detail.
- Trichuriasis (whipworm).
Cutaneous larva migrans is a skin infection that causes a rash. It can be caused by the larvae of various nematodes that get into the skin.
The number of roundworm infections throughout the world is generally increasing but varies according to levels of poverty, natural disasters and human conflicts. The spread of infection is also increasing in line with increased travel and mobility. In areas where roundworms are common, children can be continuously infected. As some worms die and are passed out in the stools (faeces), others may be growing to take their place.
Where do roundworms come from?
The life cycle of roundworms varies between types (species).
Soil and water supplies may become contaminated with roundworm eggs in areas of poor sanitation. Many roundworms have a complicated life cycle that includes both main hosts (large mammals such as humans or pigs) and intermediate hosts (small animals such as snails). Therefore, some roundworm infections occur as a result of eating uncooked contaminated food.
The eggs may survive for years in moist soil. In the soil the eggs develop into tiny young worms (larvae). Larvae can get into the human gut if you eat them with contaminated food. They pass into the bloodstream and are carried to other parts of the body - such as the lungs.
Larvae develop further and then often travel back to the gut, where the larvae then grow into adult worms. If you have worms in your gut, the female worm lays many tiny eggs. You pass these out with the stools (faeces).
The symptoms depend on the types (species) of roundworm causing the infection.
- Many affected people have no symptoms.
- Heavy roundworm infection in children can cause nutritional problems resulting in poor growth and poor general well-being.
- Some affected people may develop one or more of the following:
- High temperature (fever).
- Allergic rash (urticaria).
- Abdominal (tummy) pains.
- Feeling sick (nausea), being sick (vomiting) and/or diarrhoea.
- Nerve problems.
- The larvae in the lungs can sometimes cause symptoms such as wheeze, cough and other chest problems.
- Other symptoms are specific to the different species of roundworm. For example, onchocerciasis can cause eye lesions, which may cause total loss of vision.
- Occasionally, roundworms cause a severe illness. For example, large numbers of worms can cause a blockage in the gut. In some people, roundworms cause serious infections to the liver or pancreas, or serious allergy symptoms.
Control of roundworm infections is based on treatment with medication, improved sanitation and health education. Treatments usually work well but wiping out (eradication of) roundworm infections from tropical countries presents a major challenge. However, some eradication programmes (notably for guinea worm disease) have been effective in reducing the burden of infection.
How to get rid of roundworms in humans
- Mebendazole is the usual medicine used for children aged over 1 year, and for adults who are not pregnant or breastfeeding. It comes as a tablet or drink. You take a dose twice a day for three days. (Note: mebendazole is recommended in UK guidelines for treatment from the age of 1 year. However, strictly speaking, it is not licensed for use in children younger than 2 years of age).
- Other medicines such as albendazole, levamisole, and ivermectin are used in countries where roundworms are common. They are not often used in the UK unless under the advice of a specialist.
- Diethylcarbamazine or ivermectin is used for people with infection with filariasis.
- For pregnant or breastfeeding women and newborn babies - your doctor will advise.
Can roundworms be prevented?
In countries where roundworms are common, roundworms may be prevented by eating only cooked food and by avoiding green vegetables and salads. It is best if children do not play in areas of poor sanitation, or where human stool (faeces) is used as fertiliser. Always wash hands before eating or preparing food, and after going to the toilet or changing nappies.
If there is a high risk of infection, taking preventative medicine may be advised. For example, if you stay in an area known to be contaminated, or if you travel abroad to at-risk areas.
Further reading and references
Roundworm; NICE CKS, January 2015 (UK access only)
Parasites A-Z; Centers for Disease Control and Prevention
Parasites and Health; Centers for Disease Control and Prevention
Bethony J, Brooker S, Albonico M, et al; Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 2006 May 6367(9521):1521-32.
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