Can I take 12.5mg and Bisoprolol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking sildenafil (Viagra) and bisoprolol together can cause your blood pressure to drop lower than intended. This may make you feel dizzy, light-headed, faint, or cause a headache.
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Why this happens
Both medicines work to widen or relax blood vessels, though they do so in different ways. Bisoprolol is a beta-blocker used for heart rate and blood pressure, while sildenafil relaxes the smooth muscle in blood vessel walls. When combined, their effects add together, leading to a more significant reduction in blood pressure.
What you should do
You can usually take these together, but you should use caution. Start with the lowest possible dose of sildenafil. When you first start taking them together, be careful when standing up quickly from a sitting or lying position. If you feel very dizzy or faint, sit or lie down immediately and contact your doctor. Always ensure your doctor knows you are taking bisoprolol before they prescribe sildenafil.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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