Can I take Creon 25000 and Solifenacin together?
Drug interaction guide
Originally published 25 Jan 2026
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There are no known direct interactions between Creon 25000 and solifenacin. They work in different ways and do not interfere with how the body processes each other.
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Why this happens
Creon contains digestive enzymes that work locally in the gut to help break down food. Solifenacin is an antimuscarinic medicine used to treat overactive bladder by relaxing the bladder muscles. Because they target different systems and are processed through different pathways in the body, they do not clash.
What you should do
You can safely take these two medicines together. It is usually best to take Creon with a meal or snack as directed, while solifenacin can be taken with or without food. If you notice any new or unusual symptoms, such as severe constipation, speak to your doctor or pharmacist.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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