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Can I take Danazol and Lanzoprole together?

Drug interaction guide

Lansoprazole reduces the amount of acid in your stomach. Danazol needs a certain level of stomach acid to be absorbed properly into your bloodstream. Taking these together may mean your body does not absorb enough danazol, making it less effective at treating your condition.

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Why this happens

Lansoprazole is a proton pump inhibitor (PPI) that increases gastric pH. Danazol is a highly lipophilic drug with pH-dependent solubility; a more alkaline environment in the stomach can significantly decrease its dissolution and subsequent absorption.

What you should do

Speak to your doctor or pharmacist before taking these together. They may suggest monitoring your symptoms more closely to ensure the danazol is still working, or they may recommend a different way to manage your stomach acid.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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