Can I take Lercanidipine and Levothyroxine 25 together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known direct interaction between lercanidipine and levothyroxine. Taking these two medicines together is generally considered safe and they do not interfere with how each other works in the body.
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Why this happens
Lercanidipine is a calcium channel blocker used for high blood pressure, and levothyroxine is a hormone replacement for an underactive thyroid. They are processed by different pathways in the liver and do not compete for absorption or excretion.
What you should do
You can continue to take both medicines as prescribed by your doctor. It is usually best to take levothyroxine on an empty stomach, first thing in the morning, at least 30 to 60 minutes before breakfast or taking other medications like lercanidipine, to ensure it is absorbed properly.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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