Cetirizine for allergies
Piriteze, Zirtek,
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 12 Jan 2023
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Cetirizine relieves allergic symptoms.
Cetirizine is called a non-drowsy antihistamine; however, it can still cause drowsiness in a few people.
Make sure your reactions are normal before you drive, or before using tools or machines.
At a glance
Cetirizine is an antihistamine used to relieve allergy symptoms like hay fever or hives.
It works by blocking histamine, a chemical that causes allergy symptoms.
Common side effects include feeling tired, dizzy, headache, and dry mouth.
Although non-drowsy, it can cause sleepiness, so avoid driving if affected.
Avoid or limit alcohol intake as it can increase drowsiness.
Always check with a doctor or pharmacist if you are pregnant, have kidney problems, or are taking other medicines.
In this article:
Video picks for Allergy medicines
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Overview
Type of medicine | An antihistamine (non-drowsy) |
Used for | Allergies, such as hay fever and some allergic skin reactions |
Also called (UK) | Allacan®; Benadryl® Allergy; Piriteze® Allergy; Pollenshield® Hayfever; Sentanase® Allergy; Ziralton® Allergy; Zirtek®; Zirtek® Allergy |
Also called (USA) | All Day Allergy®; Alleroff®; Wal-Zyr®; Zyrtec®; Zyrtec® Allergy |
Available as | Capsules, tablets and oral liquid medicine |
What is cetirizine used for?
Back to contentsCetirizine is a type of antihistamine that is used to relieve symptoms of allergies such as hay fever or urticaria (hives).
It is available on prescription from a doctor or dentist, or to buy without a prescription from pharmacies and other shops.
Cetirizine comes as tablets, capsules, and liquid medicine. Liquid formulations are usually suitable for younger children, although cetirizine is not recommended for children under 2 years old.
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How does cetirizine work?
Back to contentsCetirizine works by blocking the effects of histamine - a chemical that is released when your body is exposed to substances such as pollen, pet fur, house dust, detergents, or insect bites.
Histamine causes allergy symptoms such as sneezing, itching, watery eyes, skin rashes, and a runny nose. By blocking histamine, cetirizine helps relieve these symptoms.
Side effects of cetirizine
Back to contentsCommon side effects of cetirizine include:
Feeling tired or sleepy.
Dizziness.
Dry mouth.
Headache.
Feeling sick (nausea).
Stomach pain.
Children may also experience additional side effects such as:
Diarrhoea.
Sore throat.
Nose irritation.
A full list of the side effects which can be associated with your medicine can be found in the manufacturer's printed information leaflet supplied with the medicine.
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How to manage cetirizine side effects
Back to contentsCetirizine side effects (these affect fewer than 1 in 10 people) | What can I do if I experience this? |
Feeling tired, sleepy, or dizzy | Do not drive and do not use tools or machines while affected. Do not drink alcohol |
Dry mouth | Try chewing sugar-free gum or sucking sugar-free sweets |
Headache | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, speak with your doctor |
Feeling sick, stomach (abdominal) pain | Stick to simple meals - avoid fatty or spicy foods |
Diarrhoea (in children) | Drink plenty of water |
Sore throat, nose irritation (in children) | Speak with a doctor if troublesome |
If you experience any other symptoms which you think may be due to cetirizine, speak with your doctor or pharmacist for further advice.
Who should not take cetirizine?
Back to contentsTo make sure that this is the right treatment for you (or your child), before you (or they) start taking cetirizine it is important that you discuss the treatment with a doctor or pharmacist if:
You are pregnant, trying for a baby or breastfeeding.
You/they have any kidney problems. If so, the recommended dose will be reduced.
You/they have epilepsy.
You/they have a rare inherited blood disorder called porphyria.
You/they are taking or using any other medicines. This includes any medicines being taken which are available to buy without a prescription, as well as herbal and complementary medicines.
You/they have ever had an allergic reaction to another antihistamine, or to any other medicine.
How to take cetirizine
Back to contentsRead the leaflet in your medicine pack before starting treatment.
Take cetirizine exactly as directed on the label or by your doctor or pharmacist.
Recommended doses of cetirizine are:
For adults and for children aged over 12 years: 10 mg taken once a day.
For children aged 6-11 years: 5 mg taken twice daily.
For children aged 2-5 years: 2.5 mg taken twice daily.
If using liquid medicine for a child, measure doses carefully using the bottle instructions.
Cetirizine can be taken with or without food. Swallow tablets with water if needed.
If you miss a dose, take the next one when due. Do not take two doses at the same time.
Getting the most from your treatment
Back to contentsMost people only need cetirizine for a short time. Stop taking it once your symptoms improve.
Although it is a “non-drowsy” antihistamine, it can still cause sleepiness in some people. If this happens, do not drive, cycle, or use tools or machinery.
Be careful with alcohol, as it can increase drowsiness and side effects.
Tell your doctor or healthcare provider you are taking cetirizine before any surgery, medical treatment, or allergy tests.
Check with a pharmacist before taking other medicines, as some can increase side effects when combined with cetirizine.
How to store cetirizine
Back to contentsKeep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Frequently asked questions
Back to contentsHow long does cetirizine take to work?
Cetirizine usually starts working within 30–60 minutes. It can help relieve allergy symptoms such as sneezing, itching, and watery eyes fairly quickly, with full effect within a few hours.
How long does cetirizine last?
A single dose of cetirizine usually lasts around 24 hours. This is why it is typically taken once daily for ongoing allergy relief.
Can you take cetirizine every day?
Yes, cetirizine can be taken daily if needed for allergies. However, it is usually used for short-term symptom relief. Speak to a doctor or pharmacist if you need it for long periods.
Can cetirizine make you sleepy?
Yes, although it is classed as a non-drowsy antihistamine, cetirizine can still cause drowsiness in some people. If this happens, avoid driving or using machinery.
Can you take cetirizine with alcohol?
It’s best to avoid or limit alcohol while taking cetirizine. Alcohol can increase drowsiness and make side effects like dizziness more likely.
Can you take cetirizine while pregnant?
Cetirizine can sometimes be used in pregnancy, but only if advised by a doctor. Always check with a healthcare professional before taking it.
Important information about all medicines
Back to contentsImportant information about all medicines
If you buy any medicines check with a pharmacist that they are safe to take with your other medicines.
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
What is histamine and why does cetirizine block it?
Histamine is a chemical your body releases when it encounters substances like pollen, pet fur, or insect bites. It causes common allergy symptoms such as sneezing, itching, watery eyes, skin rashes, and a runny nose. Cetirizine works by blocking the effects of histamine which helps to relieve these symptoms.
Are there different forms of cetirizine available, and are they suitable for children?
Yes, cetirizine is available as capsules, tablets, and oral liquid medicine. The liquid formulations are usually a good option for younger children. However, cetirizine is not recommended for children under 2 years old.
What should I do if I forget to take a dose of cetirizine?
If you miss a dose of cetirizine, you should take the next one when it is due. It is important not to take two doses at the same time to make up for a missed dose.
Can I stop taking cetirizine once my allergy symptoms improve?
Yes, most people only need to take cetirizine for a short period. You can stop taking it once your allergy symptoms get better.
Is it safe to take cetirizine if I have kidney problems or epilepsy?
If you have any kidney problems, the recommended dose of cetirizine will need to be reduced. If you have epilepsy, it is important to discuss this with a doctor or pharmacist before starting treatment to make sure cetirizine is appropriate for you.
Should I tell my doctor or healthcare provider that I'm taking cetirizine before medical procedures or allergy tests?
Yes, you should inform your doctor or healthcare provider that you are taking cetirizine before any surgery, medical treatment, or allergy tests. This is an important step to ensure your safety and the effectiveness of any procedures or tests.
Further reading and references
- Manufacturer's PIL, Piriteze® Allergy Tablets (GSL); GlaxoSmithKline Consumer Healthcare, The electronic Medicines Compendium. Dated March 2022.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 11 Jul 2027
12 Jan 2023 | Latest version

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