Loteprednol eye drops for inflammation
Lotemax
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 18 May 2024
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Loteprednol eye drops are prescribed to treat inflammation following eye surgery.
Use the drops four times a day, starting 24 hours after the eye surgery. Shake the bottle well before use.
Eye drops can cause blurred vision when first put in. Do not drive and do not use tools or machines until your vision is clear again.
At a glance
Loteprednol eye drops are steroid drops used for short-term eye inflammation after surgery.
They help to relieve inflammation, redness, and irritation in the eye.
Do not use them for longer than 14 days unless your doctor advises you to.
If you wear contact lenses, you should not wear them until your doctor says it is safe.
Blurred vision can occur initially; ensure clear vision before driving or using tools.
If symptoms do not improve or worsen, consult your doctor.
Eye drops only last for four weeks after opening.
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About loteprednol eye drops
Type of medicine | Corticosteroid eye drops |
Used for | To treat eye inflammation following eye surgery |
Also called | Lotemax® |
Available as | Eye drops |
Loteprednol eye drops are used short-term following eye surgery. The drops contain a corticosteroid (sometimes called a 'steroid') which helps to relieve inflammation, redness and irritation.
Before using loteprednol eye drops
Back to contentsTo make sure this is the right treatment for you, before you start using the eye drops it is important that your doctor knows:
If you have ever had an allergic reaction to any eye drops or other medicine.
If you think you may have an eye infection.
If you wear soft contact lenses.
If you are pregnant or breastfeeding.
If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
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How to use loteprednol eye drops
Back to contentsWash your hands before you use the drops.
Shake the bottle well and then remove the cap.
Tilt your head back a little and pull the lower lid of your eye out to form a pocket.
Hold the bottle upside down near to your eye. Try not to touch your eye as you do this.
Apply enough pressure to release one drop into your eye. Only use a second drop if the first drop missed going into your eye.
Close your eye for a minute or two, and press gently on the side of your nose where the corner of your eye meets your nose. This helps to stop the drop from draining away and keeps it in your eye.
Repeat the process in your other eye if you have been told to use the drops in both eyes.
Replace the cap.
Getting the most from your treatment
Back to contentsBefore you use the eye drops, read the manufacturer's printed information leaflet from the pack. It will give you more information about the eye drops and will provide you with a full list of the side-effects which you may experience from using them.
Use the eye drops exactly as your doctor tells you to. Unless you have been told otherwise, use the drops four times a day.
Loteprednol eye drops are only meant to be used for a short period of time (no longer than 14 days). Do not use them for longer than your doctor has told you to. This is because they can cause problems within your eye when used for longer than recommended. If you have been asked to use the drops for longer than 10 days, your doctor may arrange for you to have the pressure in your eyes checked.
Take care not to touch the tip of the dropper with your eye, fingers or any other surface. This will help to prevent the risk of infection.
When first put in, eye drops can cause blurred vision. This should quickly clear but make sure you can see properly before you drive and before you use tools or machines, as otherwise you may put yourself and others at risk.
If you are using any other eye drops or ointments, leave about ten minutes between applying each one. This is to prevent more liquid going into your eye than it can handle. Otherwise the drops will overflow from your eye and may not have the intended effect.
If your symptoms do not improve within a few days, or if they become worse, speak again with your doctor.
If you normally wear contact lenses, do not wear them again until your doctor advises you do so. There are two reasons for this - you should not wear lenses while your eyes are inflamed, and bottles of eye drops contain a preservative which can affect some soft contact lenses.
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Can loteprednol eye drops cause problems?
Back to contentsAlong with their useful effects, eye drops can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with loteprednol eye drops. You will find a full list in the manufacturer's information leaflet supplied with your drops. Unwanted effects often improve as your body adjusts to a new medicine but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common loteprednol eye drop side-effects | What can I do if I experience this? |
Mild discomfort, irritation or dryness | This should quickly pass. If the discomfort continues, speak with your doctor |
Blurred vision | This usually passes within a few minutes. Do not drive and do not use tools unless you can see clearly |
Headache | Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know |
Important: occasionally people can be allergic to eye drops, particularly if the eye drops contain a preservative. If you notice a rash around your eyes, or any swelling or itching, stop using the drops and contact a doctor or pharmacist for advice. Long-term use of preserved eye drops may lead to eye irritation and symptoms of dry eyes. If your eyes or eyelids become red or inflamed after using the drops, contact your doctor for advice.
If you experience any other symptoms which you think may be due to the eye drops, speak with your doctor or pharmacist for further advice.
How to store loteprednol eye drops
Back to contentsKeep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Eye drops only keep for four weeks once the bottle has been opened so throw away the bottle after this time, even if there is some solution left. This will help to prevent the risk of eye infections.
Important information about all medicines
Back to contentsImportant information about all medicines
If you suspect that someone has swallowed some of this medicine, contact the accident and emergency department of your local hospital for advice.
Do not use more than the prescribed dose.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are using.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you buy any medicines, check with a pharmacist that they are safe to use with your other medicines.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
Can I use loteprednol eye drops if I have an eye infection?
No, it is important to inform your doctor if you suspect you have an eye infection before starting loteprednol eye drops. The drops are not suitable for use in the presence of an infection.
How long can I continue to use loteprednol eye drops?
Loteprednol eye drops are intended for short-term use, typically no longer than 14 days, following eye surgery. You should follow your doctor's instructions exactly and not use them for a longer period than recommended, as prolonged use can cause problems within your eye.
What should I do if the blurred vision caused by the eye drops doesn't clear quickly?
Blurred vision usually clears quickly after putting in the eye drops. If it doesn't, ensure you can see properly before driving or operating tools and machinery to avoid putting yourself or others at risk. If the blurred vision continues to be an issue, you should speak with your doctor.
Why do I need to press on the side of my nose after applying the drops?
Pressing gently on the side of your nose, where the corner of your eye meets your nose, for a minute or two helps to keep the eye drop in your eye. This stops the solution from draining away too quickly, allowing it to have the intended effect.
What should I do if my eye symptoms don't improve or get worse while using loteprednol eye drops?
If your symptoms do not improve within a few days or if they become worse, you should contact your doctor again for further advice.
Are there any specific concerns if I am on other medications?
Yes, it's important to tell your doctor about all other medicines you are taking, including those bought without a prescription, as well as herbal and complementary medicines. This ensures loteprednol eye drops are a suitable treatment for you and helps to avoid potential interactions.
How should I dispose of any leftover loteprednol eye drops?
Eye drops only remain effective and safe for four weeks after the bottle has been opened. You should throw away the bottle after this time, even if there is still some solution left, to prevent the risk of eye infections. Do not keep out-of-date or unwanted medicines; take them to your local pharmacy for proper disposal.
Further reading and references
- Manufacturer's PIL, Lotemax® 0.5% Eye Drops; Bausch & Lomb U.K Limited, The electronic Medicines Compendium. Dated August 2022.
- Medicines Complete BNF 89th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
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About the authorView full bio

Michael Stewart, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 26 Apr 2027
18 May 2024 | Latest version

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