Pilocarpine tablets

About pilocarpine

Pilocarpine is prescribed to relieve dry mouth (sometimes called xerostomia) brought on by radiotherapy to the head or neck.

Pilocarpine can also be used to relieve some of the symptoms of Sjögren's syndrome. Sjögren's syndrome can cause various symptoms, the most common being dry eyes and dry mouth. These symptoms are due to lack of secretions from glands in your body.

Pilocarpine tablets stimulate your glands to produce more saliva and tears.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking pilocarpine it is important that your doctor knows:

• If you are pregnant or breastfeeding.

• If you have a heart condition or blood vessel disease.

• If you have a problem with the way your kidneys work, or a problem with the way your liver works.

• If you have asthma, COPD, or any other breathing problem.

• If you have a stomach ulcer, gallstones, or a problem with your bile duct.

• If you have an eye condition such as increased pressure in your eye (glaucoma), or inflammation of the iris of your eye (iritis).

• If you get confused easily.

• If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

• If you have ever had an allergic reaction to a medicine.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about pilocarpine, and will also provide you with a full list of side-effects which you could experience from taking it.

• Your doctor will tell you how often to take the tablets - take them exactly as your doctor directs. As a guide:

  • If you are taking pilocarpine following radiotherapy, it is likely you will be prescribed one tablet three times daily to begin with. Take your doses during (or straight after) a meal, and make sure you take your last dose of the day with your evening meal.

  • If you are taking pilocarpine because you have Sjögren's syndrome, the usual dose is one tablet four times daily. Take a tablet with each of your three main meals, and also one at bedtime. Although these are the usual starting doses for people taking pilocarpine, your doctor may increase your dose if it is appropriate for you.

• Every time you take a tablet, drink a large glass of water with it. This is to prevent you from becoming dehydrated, as pilocarpine can make you sweat more than usual.

• If you forget to take a dose, take it as soon as you remember unless your next dose is due. If it is nearly time for your next dose, don't take the forgotten dose but instead wait and take the next dose as normal. Do not take two doses together to make up for the missed dose.

• Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

• If after taking pilocarpine for a couple of months you feel that your condition has not greatly improved, you should let your doctor know about this. Pilocarpine will not be effective if the glands in your mouth or eyes cannot be sufficiently stimulated to produce more saliva or tears.

• If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking pilocarpine.

• If you buy any medicines 'over the counter', check with a pharmacist that they are suitable for you to take alongside pilocarpine.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains the most common ones associated with pilocarpine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any continue or become troublesome.

If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice.

• Keep all medicines out of the reach and sight of children.

• Store in a cool, dry place, away from direct heat and light.