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Piracetam

Nootropil

Piracetam has a bitter taste, so swallow the tablets whole. If you are taking liquid medicine, drink a glass of water or a soft drink afterwards.

The normal starting dose is nine tablets (three tablets in the morning, three at midday and three in the evening). Your dose may be increased further over the first few weeks.

The most common side-effects are putting on weight and feeling nervous.

At a glance

  • Piracetam is a medicine used to control involuntary movements, especially with cortical myoclonus.

  • It is thought to protect the cerebral cortex, the part of the brain responsible for thoughts and actions.

  • You will be prescribed tablets usually taken two or three times daily.

  • Do not stop taking piracetam suddenly, as symptoms may return.

  • Common side-effects include weight increase, feeling nervous or shaky, and sleepiness.

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About piracetam

Type of medicine

GABA analogue

Used for

To control involuntary movements

Also called

Nootropil®

Available as

Tablets

Piracetam acts on your brain and nervous system. It is thought to protect the part of your brain called the cerebral cortex against a lack of oxygen. The cerebral cortex is responsible for your thoughts and actions and plays a role in your movement, reasoning, perception and recognition.

Piracetam is used, alongside other medicines, to treat a movement disorder called cortical myoclonus. This condition causes short jerky muscle movements, particularly in your arms and legs.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking piracetam it is important that your doctor or pharmacist knows:

  • If you are pregnant, trying for a baby or breastfeeding.

  • If you have a blood clotting problem.

  • If you have any kind of unusual bleeding or if you have recently had surgery.

  • If you have ever had a bleed on the brain (a haemorrhage).

  • If you have been told you have a type of movement disorder called Huntington's chorea.

  • If you have problems with your kidney or liver.

  • If you are on a controlled salt (sodium) diet.

  • If you are taking thyroid hormones.

  • If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

  • If you have ever had an allergic reaction to a medicine.

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  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about piracetam and a full list of side-effects which you may experience from taking it.

  • Take piracetam exactly as your doctor tells you to. It is usually taken two or three times daily. The normal starting dose is nine tablets (three tablets in the morning, three at midday and three in the evening). Your dose may be increased over the first few weeks, and if so, your doctor will tell you how much to take and when to take it. Your dose will also be on the label of the pack to remind you, but if you are unsure about what to do, ask your pharmacist for further advice.

  • Swallow the tablets with a drink of water. Do not break or chew the tablets, as piracetam has a bitter taste.

  • Try to take your doses at the same times each day, as this will help you to remember to take them. You can take piracetam before or after meals.

  • If you do forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case leave out the missed dose). Do not take two doses together to make up for a forgotten dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

  • Tell your doctor if your symptoms worsen or do not improve after taking piracetam.

  • Keep taking piracetam until your doctor tells you otherwise. Stopping suddenly can cause your symptoms to return, so your doctor may want you to reduce your dose gradually when this is necessary.

  • If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines.

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Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. These usually improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.

Common piracetam side-effects - these affect fewer than 1 in 10 people who take this medicine

What can I do if I experience this?

Increase in weight

Eat a well-balanced diet containing plenty of fruit and vegetables

Feeling nervous or shaky

If this becomes troublesome, speak with your doctor

Feeling sleepy

If this happens, do not drive and do not use tools or machines

If you experience any other symptoms which you think may be due to this medicine, speak with your doctor or pharmacist.

  • Keep all medicines out of the reach and sight of children.

  • Store in a cool, dry place, away from direct heat and light.

Important information about all medicines

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital at once. Take the container with you, even if it is empty.

This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.

Do not keep-out-of date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.

If you have any questions about this medicine ask your pharmacist.

Report side effects to a medicine or vaccine

If you experience side effects, you can report them online through the Yellow Card website.

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Unsure about mixing medicines?

Check for possible interactions between medicines, supplements and foods before taking them together.

Frequently asked questions

What is piracetam and how does it work?

Piracetam is a type of medicine called a GABA analogue. It works by acting on your brain and nervous system, and is believed to protect the cerebral cortex (the part of your brain responsible for thoughts, actions, movement, reasoning, perception, and recognition) from a lack of oxygen.

Why is piracetam also known as Nootropil?

Nootropil is the brand name under which piracetam is available. Piracetam is the active ingredient, and Nootropil is simply one of the trade names for this medicine.

What should I do if I am already taking other medicines?

If you are taking or using any other medicines, including those available without a prescription, as well as herbal and complementary medicines, it's important to inform your doctor or pharmacist. They need to know this before you start taking piracetam to ensure there are no unsuitable interactions.

Can I stop taking piracetam if I feel better, or if I want to reduce my dose?

You should keep taking piracetam until your doctor specifically tells you to stop. Discontinuing the medicine suddenly can cause your symptoms to return. If a reduction in dose is necessary, your doctor will advise you on how to do this gradually.

What should I do if I forget to take a dose of piracetam?

If you forget a dose, take it as soon as you remember. However, if it's nearly time for your next scheduled dose, you should skip the missed dose. Do not take two doses at once to compensate for a forgotten dose.

What are the common side effects of piracetam and what can I do about them?

Common side effects, affecting fewer than 1 in 10 people, include an increase in weight, feeling nervous or shaky, and feeling sleepy. For weight increase, eat a balanced diet. If nervousness, shakiness, or sleepiness become troublesome, or if sleepiness prevents you from driving or using machinery, you should speak with your doctor.

Further reading and references

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About the authorView full bio

Author image

Michael Stewart, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

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Sid Dajani

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

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