Piroxicam gel for pain relief
Feldene
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 27 Feb 2023
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Apply piroxicam gel three or four times daily. Gently massage it into the skin over the affected area.
Wash your hands well after using the gel.
Piroxicam gel can cause your skin to become more sensitive to sunlight than normal. Protect your skin from bright sunlight during treatment.
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About piroxicam gel
Type of medicine | A non-steroidal anti-inflammatory skin gel |
Used for | Treating pain and swelling due to strains, sprains, backache or arthritis |
Also called | Feldene® |
Available as | Skin gel |
Piroxicam is a medicine called a non-steroidal anti-inflammatory drug. It is often referred to simply as 'an anti-inflammatory', or sometimes as an 'NSAID'. It works by preventing the production of some natural chemicals in your body which cause pain and inflammation. This leaflet deals with piroxicam when it is applied topically to the skin. Piroxicam can also be taken by mouth in the form of tablets and capsules, although other medicines are usually preferred to it.
When piroxicam is applied to the skin as a gel, instead of it having an effect on all of your body, it only works on the area where you have applied it. It is absorbed into your skin and then moves deeper into areas of your body where there is inflammation (for example, your muscle). Using a topical gel means that the total amount of piroxicam in your body remains low. This in turn means that you are much less likely to have a side-effect to the medicine. Topical anti-inflammatories like piroxicam are prescribed for adults - they are not generally suitable for use by children.
Before using piroxicam
To make sure that this is the right treatment for you, before you start using piroxicam gel it is important that your doctor knows:
If you are pregnant or breastfeeding.
If you have asthma or any other allergic disorder.
If you have a skin condition - eczema, for example.
If you have ever had an allergic reaction to a non-steroidal painkiller (such as aspirin, ibuprofen, diclofenac, and indometacin), or to any other medicine.
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How to use piroxicam gel
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about piroxicam and will provide you a full list of the side-effects which you could experience from using it.
Apply a thin layer of the gel and gently massage it into the affected area. Wash your hands well after using the gel (unless you've applied it to treat your hands).
Your doctor will tell you how often to use the gel. This is usually three or four times a day. The directions will also be printed on the label of the pack to remind you about what the doctor said to you.
If you forget to apply the gel at your usual time, don't worry, just apply it when you remember and then continue as before.
Getting the most from your treatment
Try to avoid the gel coming into contact with your eyes, and do not apply it to any broken or irritated areas of your skin. If this does happen by accident, wash it off with warm water as soon as possible.
It is important that you don't cover any area of skin that has been treated with the gel with any dressings or bandages. This is because more piroxicam may be absorbed by your skin than is intended, and this could lead to unwanted effects.
Piroxicam could cause your skin to become more sensitive to sunlight than normal. Do not use sunbeds, and protect any treated areas from strong sunlight until you know how your skin reacts.
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Can piroxicam gel cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with piroxicam gel, although these do not commonly occur. The best place to find a full list of the side-effects which can be associated with the gel, is from the manufacturer's printed information leaflet supplied with it. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.
Piroxicam gel side-effects | What can I do if I experience this? |
Mild skin irritation, such as redness or itching | This should clear within a day or two. If it continues or becomes worse, speak with your doctor as soon as possible |
Skin rash | Stop using the gel and speak with your doctor |
Breathing difficulties | If you have asthma, symptoms such as wheeze or breathlessness can be made worse. Stop using the gel and speak with a doctor |
If you experience any other symptoms which you think may be due to the gel, speak with your doctor or pharmacist for further advice.
How to store piroxicam
Keep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Important information about all medicines
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Make sure that the person prescribing this medicine knows about any other medicines that you are using. This includes medicines you buy and herbal and homeopathic medicines.
If you suspect that someone has swallowed some of this medicine by accident, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are using.
If you buy any medicines, check with a pharmacist that they are safe to use with your other medicines.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.
Further reading and references
- Manufacturer’s PIL, Feldene® 0.5% w/w Gel; Pfizer Limited, The electronic Medicines Compendium. Dated May 2021.
- Medicines Complete BNF 88th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 8 Feb 2026
27 Feb 2023 | Latest version
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