Pneumococcal vaccine for babies and children
Prevenar 13
Peer reviewed by Sid DajaniLast updated by Michael Stewart, MRPharmSLast updated 13 Jan 2023
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Pneumococcal vaccine is offered as part of the UK childhood immunisation schedule. It helps to protect against infections such as pneumonia and meningitis.
The vaccine will be injected into your child's leg or upper arm.
The most common side-effects are tenderness at the site of the injection, a raised temperature (mild fever) and lack of appetite. These should soon pass.
At a glance
The pneumococcal conjugate vaccine (PCV) protects children from infections like pneumonia and meningitis.
It is part of the routine childhood immunisation program in the UK.
Children usually receive two injections, one at 12 weeks and another at one year old.
The vaccine works by stimulating the immune system to produce antibodies.
Side-effects can include a mild fever, soreness at the injection site, and irritability.
Seek urgent medical advice if your child becomes breathless or develops a rash and swelling after the injection.
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About pneumococcal vaccine
Type of medicine | Pneumococcal conjugate vaccine (PCV) |
Used for | Childhood immunisation to protect against pneumococcal infection |
Also called | Prevenar 13® |
Available as | Intramuscular injection |
Pneumococcus is a germ (bacterium) which can cause pneumonia, meningitis and some other infections. Pneumococcal infections can affect anybody, but they are particularly common in young children. Some pneumococcal infections are more serious than others.
Immunisation against pneumococcus is part of the routine childhood immunisation programme in the UK. The routine schedule consists of two injections; the first at age 12 weeks and the second at one year.
There are two types of vaccine available to protect against pneumococcal infection, but only one of these works well in young children. It is called pneumococcal conjugate vaccine (PCV). The brand name of the vaccine usually used for childhood immunisation is Prevenar 13®.
The second type of vaccine is called pneumococcal polysaccharide vaccine (PPV) and is used for adults and for children over 2 years of age. There is another separate medicine leaflet called Pneumococcal vaccine for adults which provides more information about this vaccine. Adults and children aged 2 years or over can also have PCV, although this is not routinely provided by the NHS.
The vaccine stimulates your child's immune system to make antibodies against pneumococcal infections. These antibodies then help to protect your child from illness should they become infected with pneumococcal bacteria. The vaccine protects against many (but not all) types of pneumococcal bacteria.
Before your baby is given pneumococcal vaccine
Back to contentsBefore your child is given PCV, make sure your doctor knows:
If your child has been unwell recently or has a high temperature (fever).
If your child has previously had an allergic reaction to a vaccine or medicine.
If your child has a condition that makes them bleed more than is normal, such as haemophilia.
If you have been told your child has a weakened immune system.
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How the vaccine is given
Back to contentsBefore your child is given the vaccine, ask to read the manufacturer's printed information leaflet. The manufacturer's leaflet will give you more information about the vaccine and will tell you about any side-effects which your child may experience from having it. If you have any questions about the vaccine, ask your doctor or nurse for advice.
Your child will be given two doses of the vaccine. It is usual for the first to be given at 12 weeks and the second at one year. PCV will be given on the same visit as your child's other routine vaccines, but it will be given as a separate injection.
The vaccine is usually given by injection into a muscle in their thigh or upper arm. However, if your child has a condition that makes them bleed more than normal, the vaccine can be given as an injection just underneath the skin.
Getting the most from the vaccine
Back to contentsIf your child has a high temperature (fever) or is acutely unwell at the time of a scheduled immunisation, the doctor or nurse may recommend delaying giving the vaccine. A minor illness (such as a cough, cold or snuffles) will not interfere with the vaccine. If a delay is advised, you will be given an alternative appointment for the vaccination to be given.
Children who are particularly at risk from pneumococcal infections may need to have a dose of a different type of pneumococcal vaccine when they are a little older. This will be in addition to the two routine doses of PCV. This may be recommended, for example, for a child who has previously had pneumonia and been admitted to hospital.
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Can pneumococcal vaccine cause problems?
Back to contentsAlong with their useful effects, vaccines like most medicines can cause unwanted side-effects, although not every child experiences them. Pneumococcal immunisation often causes no problems, but the table below contains some of the side-effects which may occur. You will find a full list in the manufacturer's information leaflet supplied with the vaccine. Speak with a doctor or nurse if any of the following side-effects continue or become troublesome.
Common pneumococcal vaccine side-effects | What can I do if my child experiences this? |
A raised temperature (mild fever); soreness, swelling, or redness around the site of the injection | This should soon pass. If you are concerned, speak with your doctor or health visitor who may recommend giving a dose of paracetamol |
Irritability, drowsiness or restless sleep, rash | This should soon pass |
Loss of appetite, being sick (vomiting), diarrhoea | Make sure your child has plenty to drink. If this continues, let your doctor know |
You will normally be asked by the doctor or nurse to wait several minutes after the immunisation to make sure that your child does not react badly to the vaccine. Although allergic reactions are extremely rare, you should seek urgent medical advice if your child becomes breathless, or if any swelling or a rash develops within a few days of the immunisation.
If you experience any other symptoms which you think may be due to the vaccine, speak with your doctor or pharmacist.
Report side effects to a medicine or vaccine
If you experience side effects, you can report them online through the Yellow Card website.

Unsure about mixing medicines?
Check for possible interactions between medicines, supplements and foods before taking them together.
Frequently asked questions
What kind of infections can pneumococcus cause in young children?
Pneumococcus is a type of bacteria that can lead to several infections, including pneumonia, meningitis, and other illnesses. While anyone can be affected, these infections are particularly common in young children.
How often will my child need to get this vaccine?
The routine childhood immunisation programme in the UK includes two injections for pneumococcal infection. The first dose is typically given at 12 weeks of age, with the second dose administered at one year.
Are there different types of pneumococcal vaccines, and which one is used for young children?
Yes, there are two types of pneumococcal vaccines. For young children, the pneumococcal conjugate vaccine (PCV) is used as it works best for them. The brand name commonly used is Prevenar 13®.
How does the pneumococcal vaccine protect my child?
The vaccine works by stimulating your child's immune system to produce antibodies specifically against pneumococcal infections. These antibodies then help to protect your child from getting ill if they are exposed to the bacteria. The vaccine covers many, but not all, types of pneumococcal bacteria.
Can my child receive the pneumococcal vaccine if they have a minor cold?
Yes, a minor illness such as a cough, cold, or snuffles will not interfere with the vaccine. However, if your child has a high temperature (fever) or is acutely unwell, the doctor or nurse might suggest delaying the vaccination.
Can my child still receive the vaccine if they have a bleeding disorder?
If your child has a condition that causes them to bleed more than usual, such as haemophilia, the vaccine can be given as an injection just under the skin instead of into the muscle. Make sure to inform your doctor about any such conditions.
What should I do if my child develops a high temperature after the vaccine?
A raised temperature or mild fever is a common side-effect that should pass soon. If you are concerned, you can speak with your doctor or health visitor, who might suggest giving your child a dose of paracetamol.
Further reading and references
- Manufacturer's PIL, Prevenar 13® suspension for injection; Pfizer Limited, The electronic Medicines Compendium. Dated March 2021.
- Medicines Complete BNF 89th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London.
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About the authorView full bio

Helen Allen, MPharm
Pharmacist, Medical Author
MPharm
Helen Allen qualified as a Pharmacist in 1979 and spent 3 years as the drug information leaflets' author for EMIS.
About the reviewer

Sid Dajani
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
Next review due: 12 Jul 2027
13 Jan 2023 | Latest version
10 Dec 2013 | Originally published
Authored by:
Helen Allen, MPharm

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