Propiverine will help to ease urinary symptoms such as urge, frequency, and incontinence.
The most common side-effect is a dry mouth.
It can also cause blurred vision and make you feel sleepy. If this happens to you, do not drive and do not use tools or machines while affected.
|Type of medicine||An antimuscarinic medicine|
|Used for||Urinary symptoms such as frequency, urgency and incontinence|
|Available as||Tablets and prolonged-release capsules|
Propiverine is prescribed for people who have difficulty controlling their bladders. It is given to treat symptoms such as urgency, frequency and incontinence. Urinary urgency occurs when you have a sudden and urgent need to pass urine. If you need to take more trips to the toilet than normal, this is called urinary frequency. If you leak urine before you go to the toilet, this is called incontinence.
There are several different causes of these urinary symptoms, such as weakened pelvic floor muscles, problems causing your bladder muscles to contract too much or too early and medical conditions such as multiple sclerosis.
Propiverine works by stopping sudden bladder muscle contractions and increasing the volume of urine that your bladder can hold. This helps to control the release of urine and eases your symptoms.
Before taking propiverine
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking propiverine it is important that your doctor knows:
- If you are pregnant or breastfeeding.
- If you have a heart condition, such as an unusual heart rhythm, problems with the blood vessels in your heart, or heart failure.
- If you have any problems with the way your liver works or with the way your kidneys work.
- If you have any problems with your prostate gland.
- If you have any of the following conditions: increased eye pressure (called glaucoma); hiatus hernia; an overactive thyroid gland; high blood pressure; a condition causing muscle weakness, called myasthenia gravis.
- If you have a condition which could cause a blockage in your stomach, bowel or urinary tract.
- If you have ever had an allergic reaction to a medicine.
- If you are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.
How to take propiverine
- Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about propiverine and will provide you with a full list of the side-effects which you may experience from taking it.
- Take propiverine exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you, but if you are unsure about how to take propiverine, please ask your pharmacist to explain it to you again.
- If you have been given tablets (brand name Detrunorm®), you will be asked to take one 15 mg tablet one, two, or three times a day, depending upon your symptoms. It is recommended that you take the tablets before meals.
- If you have been given modified-release capsules (brand name Detrunorm® XL), you will be asked to take one capsule every day. You can take the capsule either before or after a meal. You should swallow the capsule whole - do not chew or crush it before you swallow as the capsule has been specially made to release propiverine evenly over the day. There are two strengths of capsule available: 30 mg and 45 mg.
- Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly. If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
Getting the most from your treatment
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.
- Drinks containing caffeine (for example, tea, coffee, hot chocolate and cola) may make your symptoms worse. This is because caffeine increases urine flow (it is a natural diuretic) and will make you want to pass urine. If you drink a lot of caffeine-containing drinks, consider switching to decaffeinated alternatives.
- Try to maintain a normal life as much as possible with regard to drinking and visiting the toilet. However, drinking late at night may mean your sleep is disturbed by the desire to get up and go to the toilet, so you may want to avoid drinking too much during the evening.
- Your doctor may suggest that you do some pelvic floor exercises to strengthen the muscles around the underside of your bladder. These can help to improve your symptoms.
- If you buy any medicines or herbal remedies, always check with a pharmacist that they are suitable to take with propiverine. Some medicines (particularly antihistamines) can increase the chance that you will experience unwanted effects such as a dry mouth, constipation and feeling sleepy.
Can propiverine cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the common ones associated with propiverine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
|Very common propiverine side-effects (these affect more than 1 in 10 people)||What can I do if I experience this?|
|Dry mouth||Try chewing sugar-free gum or sucking sugar-free sweets|
|Common propiverine side-effects (these affect fewer than 1 in 10 people)||What can I do if I experience this?|
|Blurred vision, feeling tired||Do not drive and do not use tools or machines while affected|
|Headache||Ensure you are drinking the recommended amount of water each day. Ask your pharmacist to recommend a suitable painkiller. If the headaches continue, let your doctor know.|
|Constipation, indigestion, tummy (abdominal) pain||Eat simple meals - avoid rich or spicy foods|
If you experience any other symptoms which you think may be due to propiverine, please speak with your doctor or pharmacist for further advice.
How to store propiverine
- Keep all medicines out of the reach and sight of children.
- Store in a cool, dry place, away from direct heat and light.
Important information about all medicines
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
If you are having an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.
This medicine is for you. Never give it to other people even if their condition appears to be the same as yours.
Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you.
If you have any questions about this medicine ask your pharmacist.
Further reading and references
Manufacturer's PIL, Detrunorm® 15 mg Tablets; ADVANZ Pharma (formerly Concordia International), The electronic Medicines Compendium. Dated May 2017.
Manufacturer's PIL, Detrunorm® XL 30 mg Modified-release Capsules; ADVANZ Pharma (formerly Concordia International), The electronic Medicines Compendium. Dated February 2019.
British National Formulary, 81st Edition (Mar 2021); British Medical Association and Royal Pharmaceutical Society of Great Britain, London.