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Can I take 0.2mg and Mirtazapine together?

Drug interaction guide

Taking mirtazapine and tamsulosin together can cause your blood pressure to drop too low, especially when you stand up from a sitting or lying position. This can make you feel dizzy, lightheaded, or faint. Both medications can also cause drowsiness, and taking them together may make you feel more tired or less alert than usual.

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Why this happens

Tamsulosin works by relaxing muscles in the blood vessels, which lowers blood pressure. Mirtazapine can also cause a drop in blood pressure (orthostatic hypotension) as a side effect. When used together, these effects add up. Additionally, both drugs affect the central nervous system, leading to increased sedation.

Use caution when combining these medicines. When getting out of bed or rising from a chair, do so slowly to avoid dizziness. If you feel faint, sit or lie down immediately. Avoid driving or operating machinery until you know how this combination affects you. If you experience severe dizziness or fainting, contact your doctor.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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