Skip to main content

Can I take 1.5mg and Rovastastatin together?

Drug interaction guide

Taking rosuvastatin and colchicine together can increase the risk of a rare but serious muscle condition called rhabdomyolysis. This causes muscle tissue to break down, which can lead to severe pain, weakness, and potential kidney damage.

Video picks for Drug interactions

Continue reading below

Why this happens

Both medicines can independently cause muscle damage (myopathy). When taken together, their effects on the muscles are added together, making the risk of injury much higher. Additionally, they may compete for the same pathways in the body, leading to higher levels of the drugs in your system.

You must speak to your doctor before taking these together. If your doctor prescribes both, be very alert for any unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or feel generally unwell. If you notice these symptoms, contact your doctor immediately.

Continue reading below

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Continue reading below

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
flu eligibility checker

Ask, share, connect.

Browse discussions, ask questions, and share experiences across hundreds of health topics.

symptom checker

Feeling unwell?

Assess your symptoms online for free

Sign up to the Patient newsletter

Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.

Please enter a valid email address

By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.