Can I take 1 and Ramapril together?

Why this happens

Ramipril works by opening up blood vessels to the kidneys, while ibuprofen narrows them. When taken together, they can 'clash', reducing blood flow to the kidneys and preventing them from filtering waste properly. Ibuprofen also causes the body to hold onto salt and water, which raises blood pressure and opposes the work of ramipril.

You should avoid taking ibuprofen while you are on ramipril unless your doctor specifically tells you to. If you need pain relief, paracetamol is usually a safer choice, but you should still limit your alcohol intake when taking it. If you have already taken both and notice you are passing less urine than usual, have swelling in your ankles, or feel unusually tired, contact your doctor.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.