Can I take 4.5mg and Clonazepam together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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Taking these two medicines together can make you feel extremely sleepy, dizzy, and confused. It can also slow down your breathing to a dangerous level and make you very unsteady on your feet, which increases the risk of falls or accidents.
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Why this happens
Both medicines act as 'depressants' on the central nervous system (the brain and nerves). When used together, their effects add up, leading to much stronger sedation and a higher risk of breathing difficulties than if either were taken alone.
What you should do
Back to contentsYou must speak to your doctor before taking these medicines together. If your doctor has prescribed both, they may need to adjust your doses. Do not drive, use tools, or operate machinery while taking this combination. Seek urgent medical help if you experience extreme sleepiness, shallow breathing, or difficulty waking up. It is also best to avoid or strictly limit alcohol, as it will make these side effects much worse.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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