Can I take 50 and Lansopraxole together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Lansoprazole can significantly reduce the amount of 5-HTP that your body absorbs. This means the 5-HTP may not work as well as it should. Additionally, combining these can sometimes lead to an upset stomach or nausea.
In this article:
Video picks for Drug interactions
Continue reading below
Why this happens
5-HTP requires a certain level of stomach acid to be broken down and absorbed properly. Lansoprazole works by reducing stomach acid, which changes the environment in your gut and prevents the 5-HTP from being taken up into your bloodstream effectively.
What you should do
Back to contentsIt is best to avoid taking these two at the same time. If you wish to take both, try to space them out by at least 2 to 4 hours. However, because 5-HTP can affect serotonin levels and lansoprazole changes stomach chemistry, you should speak to your doctor or pharmacist before using them together to ensure they are appropriate for you.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Empagliflozin and Mirtazapine together?
There is no direct interaction between empagliflozin and mirtazapine. However, both medications can occasionally cause a drop in blood pressure when you stand up (postural hypotension). Taking them together might slightly increase the risk of feeling dizzy or light-headed.

Treatment and medication
Can I take Aged garlic extract and Calcium together?
There is no known significant interaction between aged garlic extract and calcium supplements. They are generally considered safe to take together.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.