Can I take 5htp and Sitagliptin together?

Why this happens

Sitagliptin works by increasing insulin levels and decreasing glucagon levels to lower blood sugar. 5-HTP is a precursor to serotonin; while its primary effect is on mood, some studies suggest serotonin pathways can influence glucose metabolism. This could theoretically lead to unpredictable changes in blood sugar control.

You should consult your doctor or pharmacist before starting 5-HTP while taking sitagliptin. If you do take them together, monitor your blood sugar levels more frequently. Be alert for signs of low blood sugar (hypoglycaemia), such as feeling shaky, sweaty, or dizzy.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.