Can I take 60 and Bisoprolol together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking CBD (cannabidiol) with bisoprolol can cause your blood pressure to drop too low and your heart rate to slow down more than intended. You may feel dizzy, lightheaded, or faint. Additionally, CBD can interfere with how your liver breaks down bisoprolol, potentially leading to higher levels of the medicine in your blood.
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Why this happens
Both substances can lower blood pressure and heart rate (additive effect). Furthermore, CBD can block certain liver enzymes (CYP3A4 and CYP2D6) that are responsible for clearing bisoprolol from your body, which may increase the risk of side effects.
What you should do
Back to contentsYou should speak to your doctor before using CBD with bisoprolol. If you do use them together, monitor your blood pressure and heart rate regularly. Seek medical advice if you feel very dizzy or if your heart feels like it is beating very slowly. It is illegal to drive with any cannabis products (including CBD containing THC) in your system in the UK.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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