Can I take 75 and Lacidipine together?
Drug interaction guide
Originally published 14 Mar 2026
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Taking aspirin and lacidipine together can cause your blood pressure to drop lower than intended. You may also have a slightly higher risk of developing stomach irritation or bleeding, although this risk is lower with low-dose aspirin (75mg) than with higher doses.
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Why this happens
Both medicines can lower blood pressure through different methods. Lacidipine relaxes blood vessels, while aspirin can affect blood flow and kidney function. Additionally, aspirin can irritate the stomach lining, and while lacidipine doesn't directly cause ulcers, the way it affects blood flow can sometimes make the stomach more sensitive to aspirin's effects.
What you should do
Back to contentsIt is usually fine to take these together if your doctor has prescribed both, but you should use caution. Monitor your blood pressure regularly. If you feel dizzy, lightheaded, or faint (especially when standing up), speak to your doctor. You should also seek medical advice if you notice any signs of stomach irritation, such as persistent indigestion, stomach pain, or dark, tarry stools.
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Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Taking aspirin (75mg to 150mg) with Xigduo (which contains dapagliflozin and metformin) can increase the risk of your blood sugar dropping too low (hypoglycaemia). It may also increase the risk of a rare but serious condition called lactic acidosis, where too much acid builds up in your blood.

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Taking magnesium and codeine together can lead to increased drowsiness and may cause constipation. Magnesium can also slightly interfere with how your body absorbs codeine if taken at the exact same time.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

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