Can I take 75 and Omega together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
- Audio Version
Taking aspirin (75mg) and omega-3 (fish oil) together can increase your risk of bruising or bleeding. This is because both substances affect how your blood clots. While the risk is generally low at a 75mg dose of aspirin, you may notice that cuts take longer to stop bleeding or that you bruise more easily.
In this article:
Continue reading below
Why this happens
Aspirin works by stopping blood cells called platelets from sticking together to form clots. Omega-3 fatty acids also have a mild 'blood-thinning' effect by reducing platelet aggregation. When used together, these two effects add up, making the blood less likely to clot.
What you should do
Back to contentsIt is usually fine to take these together if your doctor has prescribed the aspirin, but you should use caution. Inform your doctor or pharmacist that you are taking both. Watch out for signs of unusual bleeding, such as bleeding gums, nosebleeds, or dark, tar-like stools. If you are scheduled for surgery or dental work, tell your surgeon or dentist that you take both aspirin and omega-3 supplements.
Continue reading below
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Acetaminophen and Levocetirizine together?
Taking paracetamol (acetaminophen) and levocetirizine together is generally considered safe. There are no known major interactions between these two medicines. However, both can occasionally cause drowsiness or tiredness in some people. If you experience these side effects, they may be slightly more noticeable when taking both medicines at the same time.

Treatment and medication
Can I take Abilify and Fluoxetine together?
Taking fluoxetine with Abilify (aripiprazole) can significantly increase the amount of Abilify in your bloodstream. This makes you much more likely to experience side effects such as extreme sleepiness, restlessness (feeling like you cannot sit still), uncontrollable body movements (tremors or twitching), and dizziness. There is also a small but serious risk of a heart rhythm problem called QT prolongation.
Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.