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Can I take Abervastin and Nicorandol together?

Drug interaction guide

There is no known direct interaction between atorvastatin (the generic name for Lipitor) and nicorandil. Both medications are commonly prescribed together for patients with heart disease. Atorvastatin helps lower cholesterol, while nicorandil helps open up the blood vessels to the heart.

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Why this happens

These two drugs are processed by different pathways in the body. Atorvastatin is primarily broken down by a specific liver enzyme (CYP3A4), while nicorandil is broken down through different chemical processes. They do not interfere with how each other works or how they are cleared from the system.

You can safely take these two medicines together as prescribed by your doctor. However, you should always be aware of the side effects of each. If you experience any unexplained muscle pain, tenderness, or weakness (potential side effects of atorvastatin) or severe headaches (a common side effect of nicorandil), you should contact your GP. Always inform your doctor or pharmacist of any other supplements or over-the-counter medicines you are taking.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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