Can I take Abiraterone and Doxycycline together?
Drug interaction guide
Originally published 14 Mar 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between abiraterone and doxycycline. However, abiraterone is often taken with a steroid (like prednisolone), which can sometimes affect how your body handles infections or other medications.
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Why this happens
Abiraterone and doxycycline are processed by different pathways in the liver and do not significantly interfere with each other's absorption or effectiveness.
What you should do
Back to contentsYou can take these two medicines together. Ensure you follow the specific timing instructions for abiraterone (usually taken on an empty stomach). If you have been prescribed a steroid alongside abiraterone, inform your doctor before starting the course of doxycycline.
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Important precautions
Back to contentsPregnancy and contraception
Abiraterone can cause severe birth defects. Men must use a condom and another effective method of contraception during treatment and for 3 months after stopping if their partner is pregnant or could become pregnant.
Sun exposure
Doxycycline makes your skin much more sensitive to sunlight. You must avoid direct sunlight and sunbeds, and use a high-factor sunscreen (SPF 50) to prevent severe skin reactions and burning.
Heart and liver monitoring
Abiraterone can cause high blood pressure, fluid retention, and liver damage. You must have regular blood tests and blood pressure checks as directed by your specialist.
Using other medicines
Back to contentsTaking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
14 Mar 2026 | Originally published
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