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Can I take Accrete d3 and Cymbalta together?

Drug interaction guide

Taking these two medicines together may increase the levels of calcium in your blood (a condition called hypercalcaemia). While this is not common, it can lead to symptoms like feeling sick, constipation, or feeling very thirsty.

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Why this happens

Accrete D3 contains Vitamin D, which helps your body absorb calcium. Cymbalta (duloxetine) can occasionally affect how your kidneys handle minerals or change your fluid balance. In some cases, this combination can lead to higher-than-normal calcium levels in the bloodstream.

It is generally safe to take these together, but you should have your calcium levels checked regularly by your doctor as part of your routine blood tests. If you start to feel unusually tired, thirsty, or have persistent stomach pain, contact your GP.

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Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

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Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 14 Mar 2026 | Originally published
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