Can I take Alandrosic accid and Isosorbate mononotrate together?

Why this happens

Alendronic acid is known to be very irritating to the lining of the oesophagus. Isosorbide mononitrate works by relaxing blood vessels, but it can also relax the muscle (sphincter) at the bottom of the food pipe. This can allow stomach acid to splash back up (acid reflux), which makes the irritating effects of the alendronic acid worse.

You can take both, but you must follow the safety instructions for alendronic acid very strictly. Take your alendronic acid first thing in the morning with a full glass of plain water on an empty stomach. Stay fully upright (sitting or standing) for at least 30 minutes afterwards and do not lie down until after you have eaten your first food of the day. If you develop any swallowing difficulties, new or worsening heartburn, or chest pain, stop taking the alendronic acid and speak to your doctor immediately.

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.